Thesis (MSc. (Veterinary Tropical Diseases, Veterinary Science))--University of Pretoria, 2000. / Also available in print format.

Please read the abstract in the section 00front of this document / Dissertation (MSc (Veterinary Science))--University of Pretoria, 2000. / Veterinary Tropical Diseases / unrestricted

An understanding of the potential roles as lipid mediators of a family of bioactive metabolites called N-acylethanolamines (NAEs) depends on their accurate identification and quantification. The levels of 18C unsaturated NAEs (e.g. NAE18:2, NAE 18:3, etc.) in wild-type seeds (about 2000 ng/g fw) generally decreased by about 80% during germination and post-germinative growth. In addition, results suggest NAE-degradative fatty acid amide hydrolase (FAAH) expression does not play a major role in normal NAE metabolism as previously thought. Seedlings germinated and grown in the presence of abscisic acid (ABA), an endogenous plant hormone, exhibited growth arrest and secondary dormancy, similar to the treatment of seedlings with exogenous N­lauroylethanolamine (NAE12:0). ABA-mediated growth arrest was associated with higher levels of unsaturated NAEs. Overall, these results are consistent with the concept that NAE metabolism is activated during seed germination and suggest that the reduction in unsaturated NAE levels is under strict temporal control and may be a requirement for normal seed germination and post-germinative growth.

This study seeks to provide information relevant to public policy that will lead to increased access and utilization among this vulnerable population and to reinforce the validity of the behavioral model for vulnerable populations. This study is a secondary analysis of data collected in a study that examined adult, working-aged patients within the John Peter Smith Health Network, which is a large, urban, tax supported county health care system in Fort Worth, Texas. From a sampling frame of 10,000 patients, the study analyzed data for 243 low-income, white, working-age males, collected from computer assisted telephone interviews in 2000. Cross-tabulations and bivariate logistic regressions were used to analyze the effect of 8 independent variables (age, marital status, insurance, employment status, a usual source of care, competing needs, experiences with paperwork, and perceived health status upon 5 dependent variables pertaining to unmet health care, unmet prescription medicine needs, unmet dental needs, utilization of doctors in emergency departments, and overnight hospital stays. The results show the safety net system is failing to meet the needs of this vulnerable population. The findings indicate white men who found it necessary to forgo health care due to other needs were almost five (4.973) times as likely as those who did not find it necessary to forgo care due to other needs, to report having a problem getting the health care that they need (p = ≤ .001). The odds of having a problem getting needed dental care are about 66% lower for white men who have private insurance through work compared to those who do not have private insurance through work (p ≤ .05).