Thesis (M.S.)--University of Wisconsin--Madison, 1965. / eContent provider-neutral record in process. Description based on print version record. Bibliography: l. 83-88.

Thesis (M.S.)--University of Wisconsin--Madison, 1970. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1966. / Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.

<p>Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing practices they do not meet microbial quality control standards, safety and toxicity criteria and encourage poor patients compliance. To overcome the aforementioned disadvantages of traditional dosage forms a sold dosage form, i.e. a table might be recommended. The first objective of this study was to formulate and manufacture a rapid release tablet dosage of Artemisia afra that would contain an amount of plant material equivalent to that found in its traditional liquid dosage forms and that would meet conventional pharmaceutical standards. The second objective was to conduct a pilot study to obtain a preliminary profile of the bioavailability of select flavonoids presents in both the tablet and traditional liquid preparation of Artemisia afra in humans.</p>

<p>Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing practices they do not meet microbial quality control standards, safety and toxicity criteria and encourage poor patients compliance. To overcome the aforementioned disadvantages of traditional dosage forms a sold dosage form, i.e. a table might be recommended. The first objective of this study was to formulate and manufacture a rapid release tablet dosage of Artemisia afra that would contain an amount of plant material equivalent to that found in its traditional liquid dosage forms and that would meet conventional pharmaceutical standards. The second objective was to conduct a pilot study to obtain a preliminary profile of the bioavailability of select flavonoids presents in both the tablet and traditional liquid preparation of Artemisia afra in humans.</p>

Made available in DSpace on 2014-06-11T19:25:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2012-07-06Bitstream added on 2014-06-13T19:32:31Z : No. of bitstreams: 1 000736424.pdf: 2337426 bytes, checksum: 345939e7ac9ba4726efdc45260518dd2 (MD5) / A busca da exatidão na prescrição de medicamentos representa uma preocupação na área da saúde, seja no plano mundial, ou no nacional, em razão das consequências para a saúde individual e coletiva. As prescrições médicas escritas muitas vezes de maneira incompreensível ou com ausência de informações importantes significam um sério risco para a saúde do paciente. O conhecimento sobre eventos adversos pode evitar erros caracterizados por ilegibilidade, dose e via de administração, duração de tratamento, uso de abreviaturas e interações medicamentosas. A possibilidade de ocorrência de erros na prescrição de medicamentos aumenta à medida que os profissionais envolvidos na dispensação não a conseguem ler corretamente. Neste estudo, foi analisado o perfil e a prevalência dos tipos de erros de prescrições médicas identificados em uma Farmácia Comunitária Universitária de uma Instituição de Ensino Superior na cidade de Presidente Prudente (SP), Foi realizado um estudo descritivo de desenho transversal para avaliação de 1220 documentos escritos. A análise baseou-se nos critérios pré-estabelecidos pela legislação brasileira e pela OMS. Foi identificada uma média de 1,81 medicamentos por prescrição. Em todas as prescrições analisadas foram identificadas falhas de segurança, segundo o instrumento de triagem técnica utilizado. As prescrições estavam ilegíveis ou pouco legíveis em 32,4%. Verificou-se também a ausência de informações referentes ao prescritor e ao paciente. O uso de abreviaturas estava presente em 94,5% e a denominação genérica obrigatória para o medicamento no serviço público de saúde esteve ausente em 67,8%. Os medicamentos mais prescritos pela Classificação Anatômica Terapêutica e Química (ATC) foram os do sistema cardiovascular e sistema respiratório em 18,36%, o aparelho digestivo e metabólico em 12,06%. Neste estudo, avaliaram-se os erros quanto ao processo de... / The search for accuracy in prescribing drugs is a concern in healthcare, whether in the world, or nationally, because of the consequences for the individual and collective health. Prescriptions are often written in a way incomprehensible or lack important information, which can mean a serious risk to the health of the patient. The knowledge about adverse events may prevent errors because of illegibility, dosage and way of administration, duration of treatment, use of abbreviations and drug interactions. The possibility of errors in prescribing drugs increases as the professionals involved in the dispensation cannot read properly. In this study, we analyzed the profile of the types of medical errors and its prevalence, identified in a Community Pharmacy University, an institution of higher education in the city of Presidente Prudente (SP), where a cross-sectional descriptive study was conducted to evaluate 1220 written prescriptions. The analysis was based on predetermined criteria by the Brazilian legislation and WHO. It was identified an average of 1.81 medications per prescription. In all of the prescriptions analyzed security flaws were identified according to a screening technique used. The prescriptions were unreadable or barely legible in 32.4%. It was also found to lack information regarding the prescriber and the patient. The use of abbreviations was present in 94.5% and mandatory generic name for the drug in public health service was absent in 67.8%. The most frequently prescribed medications by Anatomical Therapeutic Chemical Classification (ATC) were for the cardiovascular system and respiratory system 18.36% and 12.06% in the digestive and metabolic systems. In this study we evaluated the errors on the process of preparing the prescription and the prescriber's decision related to pharmacotherapy. Therefore, studies and strategies that contribute to improving the quality of medical prescriptions demonstrated to be relevant, in...

Orientador: Chung Man Chin / Banca: Jean Leandro dos Santos / Banca: Claudia Fegadolli / Resumo: A busca da exatidão na prescrição de medicamentos representa uma preocupação na área da saúde, seja no plano mundial, ou no nacional, em razão das consequências para a saúde individual e coletiva. As prescrições médicas escritas muitas vezes de maneira incompreensível ou com ausência de informações importantes significam um sério risco para a saúde do paciente. O conhecimento sobre eventos adversos pode evitar erros caracterizados por ilegibilidade, dose e via de administração, duração de tratamento, uso de abreviaturas e interações medicamentosas. A possibilidade de ocorrência de erros na prescrição de medicamentos aumenta à medida que os profissionais envolvidos na dispensação não a conseguem ler corretamente. Neste estudo, foi analisado o perfil e a prevalência dos tipos de erros de prescrições médicas identificados em uma Farmácia Comunitária Universitária de uma Instituição de Ensino Superior na cidade de Presidente Prudente (SP), Foi realizado um estudo descritivo de desenho transversal para avaliação de 1220 documentos escritos. A análise baseou-se nos critérios pré-estabelecidos pela legislação brasileira e pela OMS. Foi identificada uma média de 1,81 medicamentos por prescrição. Em todas as prescrições analisadas foram identificadas falhas de segurança, segundo o instrumento de triagem técnica utilizado. As prescrições estavam ilegíveis ou pouco legíveis em 32,4%. Verificou-se também a ausência de informações referentes ao prescritor e ao paciente. O uso de abreviaturas estava presente em 94,5% e a denominação genérica obrigatória para o medicamento no serviço público de saúde esteve ausente em 67,8%. Os medicamentos mais prescritos pela Classificação Anatômica Terapêutica e Química (ATC) foram os do sistema cardiovascular e sistema respiratório em 18,36%, o aparelho digestivo e metabólico em 12,06%. Neste estudo, avaliaram-se os erros quanto ao processo de ... / Abstract: The search for accuracy in prescribing drugs is a concern in healthcare, whether in the world, or nationally, because of the consequences for the individual and collective health. Prescriptions are often written in a way incomprehensible or lack important information, which can mean a serious risk to the health of the patient. The knowledge about adverse events may prevent errors because of illegibility, dosage and way of administration, duration of treatment, use of abbreviations and drug interactions. The possibility of errors in prescribing drugs increases as the professionals involved in the dispensation cannot read properly. In this study, we analyzed the profile of the types of medical errors and its prevalence, identified in a Community Pharmacy University, an institution of higher education in the city of Presidente Prudente (SP), where a cross-sectional descriptive study was conducted to evaluate 1220 written prescriptions. The analysis was based on predetermined criteria by the Brazilian legislation and WHO. It was identified an average of 1.81 medications per prescription. In all of the prescriptions analyzed security flaws were identified according to a screening technique used. The prescriptions were unreadable or barely legible in 32.4%. It was also found to lack information regarding the prescriber and the patient. The use of abbreviations was present in 94.5% and mandatory generic name for the drug in public health service was absent in 67.8%. The most frequently prescribed medications by Anatomical Therapeutic Chemical Classification (ATC) were for the cardiovascular system and respiratory system 18.36% and 12.06% in the digestive and metabolic systems. In this study we evaluated the errors on the process of preparing the prescription and the prescriber's decision related to pharmacotherapy. Therefore, studies and strategies that contribute to improving the quality of medical prescriptions demonstrated to be relevant, in... / Mestre

Magister Pharmaceuticae - MPharm / Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing practices they do not meet microbial quality control standards, safety and toxicity criteria and encourage poor patients compliance. To overcome the aforementioned disadvantages of traditional dosage forms a sold dosage form, i.e. a table might be recommended. The first objective of this study was to formulate and manufacture a rapid release tablet dosage of Artemisia afra that would contain an amount of plant material equivalent to that found in its traditional liquid dosage forms and that would meet conventional pharmaceutical standards. The second objective was to conduct a pilot study to obtain a preliminary profile of the bioavailability of select flavonoids presents in both the tablet and traditional liquid preparation of Artemisia afra in humans. / South Africa

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