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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
101

Further evidence that prostaglandin F2-alpha is the obligatory eicosanoid in porcine ovulation

Cassidy, Carrie. January 1997 (has links)
Metabolites of arachidonic acid, known as eicosanoids, result from two enzymatic pathways: cyclooxygenase (COX) and lipoxygenase (LOX). Indomethacin (INDO), at a dose level of approximately 10 mg/kg, has been commonly used in studies on the role of prostagiandins (PG) in the porcine ovulatory process since it was believed to be specific in its inhibition of the COX pathway. Other evidence suggests that INDO also has inhibitory effects on the formation of LOX metabolites including 12- and 15-hydroxyeicosatetraenoic acid (HETE). There is also evidence that LOX metabolites may have a role in the ovulatory process of the rat and the pig. In the previous studies on PGs in porcine ovulation, the effect of INDO on LOX metabolites was not examined. It has been shown that progesterone has a role in the formation of eicosanoids in the ovary in the rat and the ewe. The results of this study indicate that an intramuscular injection of INDO, at dose levels as high as 5 mg/kg, reduces ovulation rat and preovulatory follicular fluid concentrations of PGF2alpha without affecting concentrations of 12- and 15-HETE in the gonadotropin-primed pig. Indomethacin, at dose levels as low as 1 mg/kg, reduced ovulation rate and intrafollicular PGF2alpha concentrations but 0.1 mg/kg had no effect on ovulation rate or PGF2alpha. In cultured granulosa and theca interna cells, 10 ng or greater of INDO per 3 x 105 cells reduces PGF2alpha accumulation in the media. Accumulation of 12- and 15-BETE in the media was reduced by 100 ng or greater of INDO per 3 x 10 5 cells. To examine the role of progesterone in the formation of eicosanoids, danazol, an inhibitor of steroidogenesis, was added to cultures of porcine follicular cells. This treatment had no effect on progesterone production by either cell type and, similarly, had no effect on eicosanoid production. (Abstract shortened by UMI.)
102

The role of prostaglandins, nitric oxide and oxygen in the ductus arteriosi of the pre-term chicken embryo (Gallus domesticus)

Greyner, Henry José. Dzialowski, Edward M. January 2007 (has links)
Thesis (M.S.)--University of North Texas, Dec., 2007. / Title from title page display. Includes bibliographical references.
103

Prostaglandins and isoprostanes in relation to risk factors for atherosclerosis : role of inflammation and oxidative stress /

Helmersson, Johanna, January 2005 (has links)
Diss. (sammanfattning) Uppsala : Uppsala universitet, 2005. / Härtill 5 uppsatser.
104

Cellular mechanisms responsible for development of sensitivity of the bovine corpus luteum to prostaglandin F2 alpha

Goravanahally, Madhusudan P. January 2009 (has links)
Thesis (Ph. D.)--West Virginia University, 2009. / Title from document title page. Document formatted into pages; contains xvi, 218 p. : ill. (some col.). Vita. Includes abstract. Includes bibliographical references (p. 92-114).
105

Clinical applications of misoprostol in obstetrics and gynecology /

Ngai, Suk-wai, Cora. January 2000 (has links)
Thesis (M.D.)--University of Hong Kong, 2000. / Includes bibliographical references (leaves 164-189).
106

Prostaglandins and angiogenesis in experimental cancer /

Axelsson, Hans, January 2010 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2010. / Härtill 4 uppsatser.
107

Clinical applications of misoprostol in obstetrics and gynecology

Ngai, Suk-wai, Cora. January 2000 (has links)
Thesis (M.D.)--University of Hong Kong, 2000. / Includes bibliographical references (leaves 164-189) Also available in print.
108

The role of cyclooxygenase-2 and prostaglandins in bone adaptation in the rat /

Gregory, Laura. January 2005 (has links) (PDF)
Thesis (Ph.D.) - University of Queensland, 2006. / Includes bibliography.
109

Effect of lipoxin A4 and prostaglandin E2 on bone healing /

Varanasi, Srinivas. January 2005 (has links) (PDF)
Thesis (M.Phil.) - University of Queensland, 2005. / Includes bibliography.
110

Cyclooxygenase-1 derived prostaglandin E2 (PGE₂) signaling in early development

Cha, Yong I. January 1900 (has links)
Thesis (Ph. D. in Cell and Developmental Biology)--Vanderbilt University, May 2006. / Title from title screen. Includes bibliographical references.

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