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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.

Actions of estrogen and estrogen-related compounds on prostate cancer cell growth

Lee, Chun-lun., 李振倫. January 2007 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences

An analysis of the role of human chromosome 8 in carcinoma of the prostate in vivo and in vitro

Macintosh, Catherine Anne January 1998 (has links)
No description available.

Studies of voltage gated NA⁺ channel mRNA expression in rat and human carcinomas

Diss, James Kenneth Joseph January 2001 (has links)
No description available.

Isolation and characterisation of co-regulatory molecules involved in androgen receptor movement and transactivation

Ozanne, Daniel M. January 2000 (has links)
No description available.

Cause-specific failure probability with covariate effects

Choi, Kwisook January 1996 (has links)
Thesis (Ph. D.)--University of Hawaii at Manoa, 1996. / Includes bibliographical references (leaves 129-135). / Microfiche. / xv, 135 leaves, bound ill. 29 cm

In Vitro Effects of Bisphenol A on Prostate Cells: Searching for Clues of Environmental Carcinogenesis

Sienkiewicz, Marta 30 April 2012 (has links)
Estrogens maintain the appropriate androgen-estrogen balance for normal regulation of the structure and function of the male reproductive tract, including the prostate gland. This research investigated viability of cells and expression of selected genes in prostate carcinoma cells (PC-3) exposed to bisphenol A (BPA), an estrogen-like substance present in a number of plastic materials. PC-3 cells are able to metabolize BPA at concentrations below 100 µM. BPA exposure at concentrations between 1nM and 100 µM does not increase or significantly reduce cell viability of these cells. Although the genes investigated in this study (GSTP1 and MGMT) did not show a significant change in expression following in vitro exposure to BPA, the positive control ethinyl estradiol (EE2) caused an increase in GSTP1 expression at mRNA level. These results indicate that BPA does not affect the viability of prostate cells, and motivate a need for further research to identify other genes that could be affected by BPA.

MicroRNAs as Prognostic Biomarkers in Prostate Cancer

Gordanpour, Aida 12 December 2012 (has links)
Prostate cancer, one of the most common cancers among men, can be relatively harmless or extremely aggressive. The most widely used biomarker for the disease, the PSA test, is not independently diagnostic or prognostic of prostate cancer. One of the main challenges of prostate cancer research is to find reliable and effective prognostic biomarkers that will predict cancer recurrence following surgery, in order to identify clinically significant prostate cancer and improve management of the disease. In recent years, microRNAs (miRNAs) have been identified as master regulators of cellular processes, and dysregulated miRNAs have been associated with cancer development and progression. The intent of my PhD research program was to uncover novel miRNAs that contribute to prostate cancer pathogenesis in order to assess their potential as predictors of clinical progression. By analyzing a large cohort of primary prostate cancer samples, we have discovered that microRNA-221 (miR-221) is associated with metastasis and biochemical recurrence in prostate cancer, and is downregulated in TMPRSS2:ERG fusion gene- positive tumors. In addition, we have determined that microRNA-182 (miR-182) is overexpressed in prostate cancer and is associated with increased metastasis and clinical progression by targeting a tumors suppressor Forkhead box O1 (FOXO1). Overall, this work introduces novel candidate miRNA genes and downstream targets that are aberrantly expressed in more aggressive prostate cancer, and presents a potentially significant role for miRNAs as prognostic biomarkers that are associated with clinical progression, and perhaps aids in defining how miRNAs might one day serve as anti-cancer therapeutic agents.

Oncostatic actions of melatonin on tumor cell growth in the LNCaP model of human prostate cancer

Xi, Sichuan. January 2000 (has links)
Thesis (Ph. D.)--University of Hong Kong, 2001. / Includes bibliographical references (leaves.

Effects of intermittent androgen suppression therapy on cognitive functioning and quality of life in men with metastatic prostate cancer /

Khoo, Sue-Anne. January 2001 (has links) (PDF)
Thesis (M. Psych. Clin.)--University of Queensland, 2002. / Includes bibliographical references.

The influence of embryonic urogenital sinus mesenchyme on the cytodifferentiation of the dunning prostatic adenocarcinoma /

Tam, Ngai-chung, Neville. January 1995 (has links)
Thesis (M. Phil.)--University of Hong Kong, 1996. / Includes bibliographical references (leaf 135-164).

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