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Molecular characterization of protein-nucleic acid interfaces : applications in bioinformaticsLee, Semin January 2011 (has links)
No description available.
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Sex hormone-binding globulin: protein-proteininteractions and identification of a novel isoformNg, Kwong-man., 吳廣文. January 2006 (has links)
published_or_final_version / abstract / Zoology / Doctoral / Doctor of Philosophy
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Cellular proteins in picornavirus replicationBailey, Daniel John January 1999 (has links)
No description available.
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Studies on the sequence-selective nuclease, bovine pancreatic DNase IDoherty, Aidan Joseph January 1992 (has links)
No description available.
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The structure and function of translocation domain of Colicin NRaggett, Elaine January 1998 (has links)
No description available.
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Studies of specific molecular interactions within and between membrane bilayersSizer, P. J. H. January 1986 (has links)
No description available.
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Capping of the major rat thymocyte glycoproteins : Their interactions with other membrane proteins and the cytoskeletonTurner, C. E. January 1986 (has links)
No description available.
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Development of a Synthetic Biology Tool to Quantify the Contribution of Protein Components and Protein Interactions Within Transcriptional Regulatory ComplexesSimmons, Kateland 29 March 2019 (has links)
We have formed the basis for a synthetic gene regulatory network in S. cerevisiae to assess the relative contribution of proteins and protein interactions to the function of transcriptional regulatory complexes. This gene network contains two synthetic transcriptional regulator (TR) fusion proteins that control transcriptional activation and repression of a reporter expressed by a synthetic promoter. This system can be modulated and quantified specifically by our manipulations since the transcriptional regulators (TRs) are only active when drug induced. In this thesis, I characterized and optimized my gene network to enable accurate measurements of transcriptional regulation. I demonstrated that my synthetic repressor interacts with a selected native transcriptional regulatory complex. Future mutation experiments can be performed to investigate the relative importance that the selected protein interaction plays on transcriptional regulation. New synthetic repressor fusion proteins can be created to study the relative importance of protein interactions between other TRs, making this tool versatile. This tool will allow us to quantify interactions and gain a deeper understanding of the complicated mechanisms controlling transcriptional regulation.
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Approaches towards the inhibition of protein-protein interactionsHadje Georgiou, Kathy January 2015 (has links)
No description available.
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Protein-protein interactions : binding site detection using molecular dynamics simulationsTan, Yaw Sing January 2014 (has links)
No description available.
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