La diatomée Pseudo-nitzschia comprend certaines espèces toxiques capables de produire de l'acide domoïque (AD), une neurotoxine amnésiante. La prolifération de ces espèces toxiques présente de nombreux risques allant de graves dommages écologiques et économiques à des menaces pour la santé publique. Les problèmes liés à cette prolifération se multiplient dans le monde entier et le besoin de la société scientifique de mieux comprendre les facteurs environnementaux influant sur l’apparition de ces blooms est plus nécessaire que jamais. Dans ce contexte, plusieurs espèces et souches de Pseudo-nitzschia ont été étudiées afin de mieux comprendre et prédire leurs réponses physiologiques face à de futurs changements climatiques. En particulier, les expérimentations effectuées ont permis d’explorer l’impact de la variation de la salinité et de l’acidification de l’océan (diminution de pH) sur la croissance et la production d’AD chez les espèces de Pseudo-nitzschia australis et P. fraudulenta. Les résultats obtenus ont montré que les espèces de Pseudo-nitzschia sont capables de s'adapter, proliférer et produire des toxines dans des conditions variables de salinité et de pH, malgré une importante diversité de réponses en fonction des souches ou des espèces étudiées. Ces résultats ont permis de déterminer l’influence et la capacité d’acclimatation des cellules de Pseudo-nitzschia face aux futures conditions environnementales (salinité, pH). Les travaux réalisés représentent une contribution à l’avancée des connaissances sur l’écophysiologie et la production toxinique par les espèces de Pseudo-nitzschia. / The diatom Pseudo-nitzschia includes certain toxic species capable of producing domoic acid (DA), an amnesic neurotoxin. The proliferation of these toxic species presents many risks ranging from serious ecological and economic damage to threats to public health. Problems related to these proliferations are increasing worldwide and the need for scientist to better understand the environmental factors influencing the appearance of these blooms is more necessary than ever. In this context, several species and strains of Pseudo-nitzschia have been studied to better understand and predict their physiological responses to future climate change. In particular, the experiments carried out allowed to explore the impact of salinity variations and ocean acidification (decrease of pH) on the growth, photosynthesis and DA production by several Pseudo-nitzschia species and strains. The results obtained showed that Pseudo-nitzschia species are flexible, able to adapt, proliferate and produce toxins under varying conditions of salinity and pH, despite the large diversity of responses depending on the strains or species studied. These results made it possible to determine the influence and acclimation capacities of Pseudo-nitzschia cells facing future environmental conditions (pH, salinity). Thus, the work carried out represents a contribution to the advancement of knowledge on the ecophysiology and toxin production by Pseudo-nitzschia species.

On traditional filters, we usually need a trade off between low-voltage and high dynamic range. The companding filters may solve this problem. This thesis presents a pseudo-exponential third-older low pass filter. All MOSFETs are operated in saturated region to obtain high frequency. The filter has small chip area and less MOSFETs. The filter has supply voltage of 3V, has cutoff frequency of 3MHz to 10MHz, and 1.06mW power dissipation. We will first employ Hspice to simulate the log-domain filter to ensure the correctness of the circuit and make it a reliable reference with the circuit layout. After summarizing all the simulations and analyses, the chip has been fabricated with 0.35um CMOS technology.

Th.--Méd.--Amiens, 1977. N°: 108.

Thèse--Paris. / Bibliography: p. [271]-273.

No description available.

No description available.

Com a pesquisa busca-se descobrir quão estreita é a relação entre a teoria das prescrições retóricas feitas pelos progymnásmata de Élio Teão, Hermógenes, Aftônio e Nicolau e as produções escritas que nos restaram de alunos na iminência de praticar a oratória a partir do primeiro século d.C. Deste modo, pela análise dos documentos esperase, primeiro, produzir mais informações sobre como se dava o ensino de tal disciplina entre os romanos, a) indentificando os temas de que se serviam os professores, a relevância de tais produções escritas para a aprendizagem de gêneros textuais, os lugarescomuns e os autores que eram modelo a imitar ou evitar e o modo como tal ação se dava por meio das palavras; b) fornecendo tradução da invectiva de (Pseudo-)Cícero e da invectiva e das epístolas a César de (Pseudo-)Salústio. / This research aims to find out how close is the relationship between the theory of rhetorical prescriptions of Aelius Theon, Hermogenes, Aphtonius the Sophist, and Nicolaus the Sophist and remaining texts of students who were about to go on public speaking on first century A.D. Thus, the analysis of such documents is expected to give more information about rhetorical teaching among the Romans: identifying themes that served teachers, the relevance of such written productions for learning text genres, the common places and authors that were model to imitate or avoid and how such action took form through words. At last, there is a translation of the invective by (Pseudo -)Cicero and the invective and the epistles to Caesar by (Pseudo-)Sallust.

Com a pesquisa busca-se descobrir quão estreita é a relação entre a teoria das prescrições retóricas feitas pelos progymnásmata de Élio Teão, Hermógenes, Aftônio e Nicolau e as produções escritas que nos restaram de alunos na iminência de praticar a oratória a partir do primeiro século d.C. Deste modo, pela análise dos documentos esperase, primeiro, produzir mais informações sobre como se dava o ensino de tal disciplina entre os romanos, a) indentificando os temas de que se serviam os professores, a relevância de tais produções escritas para a aprendizagem de gêneros textuais, os lugarescomuns e os autores que eram modelo a imitar ou evitar e o modo como tal ação se dava por meio das palavras; b) fornecendo tradução da invectiva de (Pseudo-)Cícero e da invectiva e das epístolas a César de (Pseudo-)Salústio. / This research aims to find out how close is the relationship between the theory of rhetorical prescriptions of Aelius Theon, Hermogenes, Aphtonius the Sophist, and Nicolaus the Sophist and remaining texts of students who were about to go on public speaking on first century A.D. Thus, the analysis of such documents is expected to give more information about rhetorical teaching among the Romans: identifying themes that served teachers, the relevance of such written productions for learning text genres, the common places and authors that were model to imitate or avoid and how such action took form through words. At last, there is a translation of the invective by (Pseudo -)Cicero and the invective and the epistles to Caesar by (Pseudo-)Sallust.

Inaug.-diss.--Münster. / Lebenslauf.

Inaug.-diss.--Münster. / Lebenslauf.