During early lactation dairy cows often experience health disorders, which are usually associated with decreased production and reproduction variables. Following parturition, cows use more energy for maintenance and milk production than they consume and enter into a state of negative energy balance. Negative energy balance in early lactation is thought to contribute to decreased milk production, reduced reproductive performance, and increased health disorders. Flunixin meglumine (FM) is an anti-pyretic (fever reducing) and anti-inflammatory drug that is commonly used in the dairy industry. This study evaluated the effect of FM on pyrexia, production and bioenergetic variables in postparturient dairy cows.

The aim of this study was to evaluate temperature data collected from Thoroughbred foals between birth and shortly after weaning. It provides a valuable survey with epidemiological conclusions providing insight into the temperature trends and pyretic occurrences of Thoroughbred foals during this age period. Temperature data were collected using telemetry from temperature sensitive microchips implanted into newborn foals. The system of inputting and storing temperature data was completely electronic and this study evaluated this system. It was found that this system was stable and allowed the evaluation of large amounts of frequently acquired data with little human intervention. The data obtained resulted in the valuable evaluation of age associated body temperature trends within the foals as well as providing an indication of the extent and epidemiology of pyrexia within the study cohort. The system of evaluating temperatures based both on the individual day value as well as on each individual foals prior series of temperatures shows that the use of these two criteria can be utilised simultaneously. The study provides basic information which future researchers using similar systems can use to objectively set criteria for pyrexia. An outbreak of equine encephalosis also occurred during the study period and this provided much needed prospective epidemiological information for such an outbreak, something which has not previously been documented. Copyright / Dissertation (MSc (Veterinary Science))--University of Pretoria, 2009. / Production Animal Studies / unrestricted

Background: Infective endocarditis is a rare but severe condition associated with a high mortality rate in small animal patients. This condition is caused by a microbial (most often bacterial) infection of the valvular portion of the endocardium, from which proliferative and/or erosive lesions on the cardiac valves or immediately adjacent structures develop. The two most commonly affected cardiac valves are the aortic and mitral valves. Case presentation: We report the clinical case of a 4-year old male neutered Bull terrier, 27.6 kg, body condition score 4/9, that presented with a 3-months history of pyrexia and general weakness. The patient history also revealed a transient left hind limb lameness (grade 2/4), which coincided with the onset of clinical signs about 3 months before presentation. On physical examination, a left-sided systolic heart murmur (grade 3/6) with the same intensity at the left heart base and apex, and an irregularly irregular heart rhythm were noted. Electrocardiography showed ventricular premature complexes, and echocardiography revealed lesions consistent with endocarditis involving the aortic and mitral valve. Bacterial culture of blood yielded a positive result, and the organism isolated was identified as Erysipelothrix rhusiopathiae. The extended patient history revealed that the dog lived close to a farm housing pigs and other livestock. Conclusion: We report a rare case of the premortal diagnosis of infective bacterial endocarditis in a dog due to E. rhusiopathiae infection. Most reports about this condition are from necropsy series. This clinical case report emphasizes that E. rhusiopathiae infection and bacteremia should be considered as a differential diagnosis in dogs with suspected infective endocarditis, especially in dogs living in rural areas with access to livestock and particularly farm pigs. Also, particular emphasis should be placed on the zoonotic potential of this infectious disease.