College students experience high levels of stress, especially those in health care programs. The purpose of this study was to determine what factors contribute to Tennessee radiography student stress levels and the methods by which they cope with stress. Additionally, do demographic factors affect radiography student stress levels? The research was conducted February 4 to March 30, 2016. A survey was distributed to students in a radiography program at two and four year colleges in Tennessee. Participants were asked questions on factors that influence their stress levels, coping strategies, and health issues experienced in the past year. Descriptive statistics, independent samples t-test, and Pearson correlations were used to determine what factors influenced student stress levels, the most effective coping strategies, and if demographics affected student stress levels. This analysis revealed that school causes students the most stress, while taking a break was the most used stress coping strategy.