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Role of circulating adrenaline in the pathogenesis of hypertension / Lina Terese Jablonskis.Jablonskis, Lina Terese January 1994 (has links)
Includes copies of author's previously published works. / Bibliography: leaves 106-122. / xiii, 123 leaves : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Examines the relationship between circulating adrenaline (AD) and blood pressure. Results suggest that the elevation of circulating AD in hypertensive rats is a consequence rather than a cause of their hypertension. / Thesis (Ph.D.)--University of Adelaide, Dept. of Physiology, 1995
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The immunobiology of the rat testicular macrophageKern, Stephan, 1968- January 1996 (has links) (PDF)
Bibliography: leaves 169-205. This thesis suggests that the testicular macrophage exhibits characteristics similar to that of a suppressor macrophage phenotype. The inhibition of lymphocyte proliferation by the testicular macrophage, its unique cytokine profile, high basal production of GM-CSF and prostaglandins, and the refractoriness to LPS all suggests a role that contributes to the immune privilege that is afforded the testis. However, these aspects of testicular macrophage immuno-biology also support a role in local cell-cell communication and regulation of the normal physiology of the testis, and macrophages may be directly involved in Leydig cell steriogenesis.
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Selenoprotein W : distribution and function in rat tissue and cultured cellsSun, Yu, 1963- 27 May 1998 (has links)
The objective of this study was to further determine the distribution of
selenoprotein W (SeW) in tissues from rats and sheep fed different selenium levels and to
search for the possible functions of this protein. In the rat study a total of 28 rat tissues
were examined and SeW was found in all of the tissues except for liver, thyroid,
pancreas, pituitary and eyes regardless of the level of Se fed. SeW was not detected in
heart, lungs, prostate, esophagus, small intestine, tongue, skin diaphragm and skeletal
muscle from selenium deficient rats, but was present in these tissues when the two higher
levels of selenium (0.1 and 4.0 mg/kg) were fed. SeW has the highest expression in
muscle, brain, testis and spleen when selenium is adequate. Interestingly, selenium
deficiency resulted in undetectable SeW levels in heart and muscle from deficient sheep
and rats, but the content in brain was unaffected by selenium status. Second generation
selenium depleted and repleted rats indicated that the expression of SeW in cortex and
cerebellum was not significantly affected by selenium, but selenium increased its levels
in thalamus. Cortex had the highest SeW expression among the three parts of the rat
brain. SeW levels in muscle, spleen, skin and testis were undetectable in weanling rats,
but became detectable after 6 weeks of selenium repletion. Studies with various brain cell
cultures indicated that Se appears to be metabolized differently by different brain cell types. As demonstrated in neuroblastoma and glial cells, glutathione peroxidase (GPX)
activity decreased at a faster rate than SeW with neuroblastoma cells whereas SeW
decreased at a faster rate than GPX activity in glial cells when selenium was removed
from the media. Since other work showed that glutathione was bound to SeW, it was
speculated that it has antioxidant function similar to other selenoproteins. SeW
overexpressed and underexpressed cell lines were established by DNA recombinant
techniques. There was a greater survival rate of overexpressed cells when incubated with
2,2'-Azobis (2-amidinopropane) dihydrochloride (AAPH) than control cells, suggesting
SeW possibly has an antioxidant function. / Graduation date: 1999
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Comparison of muscle fiber type from normal and regenerated rat gastrocnemius through myosin ATPase stainingPearson, David Roy 03 June 2011 (has links)
Regeneration of the gastrocnemius muscle in 25 white rats was reinvestigated using reimplantation of minced muscle fragments in order to compare the fiber profiles of the regenerate and normal contralateral gastrocnemius. Fiber profiles were prepared from both the regenerate and the normal muscle 45 days postoperatively using myosin ATPase histochemistry.Counts made of type 1, 2A, 2B, and 2C fibers showed a significant (P<(0.05) change in the profile of the regenerated muscle compared to the contralateral muscle.The results indicated that although there was a change in the fiber profile at 45 days, the regenerated muscle appeared to follow a path of developmental recapitulation. Changes in the fiber appeared to be related to reinnervation of the regenerate.Ball State UniversityMuncie, IN 47306
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Serum creatine phosphokinase and lactate dehydrogenase activities in the rat after variable durations of downhill runningGriffith, Steven L. 03 June 2011 (has links)
Serum lactage dehydrogenase and creatine phosphokinase level were studied in sixty male Sprague-Dawley rats weighing 400 to 680 grams. Five groups of ten rats each ran forty-five minutes (16 m/min) with variable percentages of the total bout consisting of downhill running (16° incline): Group I- 0%, Group II- 22%, Group III- 50%, Group IV- 78%, Group V- 100% downhill. Group VI consisted of ten sedentary controls. Serial blood samples were obtained immediately after exercise, 12, 24, 36, 48, and 60 hours found to exist between a non-trained rat’s weight and its ability to finish the exercise bout and live beyond 48 hours.Each exercise group, except Group V, showed s significant decrease in the CPK activity at 24 and/or 36 hours post-exercise. Group V showed a significant elevation (P<0.05) in LDH and CPK activity at 12 hours. With the total exercise time remaining the same, a linear relationship was suggested between duration of downhill running and LDH activity at 12 and 24 hours post-exercise, r=0.5880 (n=26) and r=0.4490 (n=28), respectively.Ball State UniversityMuncie, IN 47306
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Mechanisms of endogenous nitric oxide production and intracellular pathways in rat hippocampal CA1 calcium response to hypoxia and in-vitro ischemiaTjong, Yung-wui., 鍾勇會. January 2004 (has links)
published_or_final_version / abstract / toc / Physiology / Master / Master of Philosophy
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Ageing and the gene expression of endothelin in the male reproductive system of the rat陳青瑜, Chan, Ching-yu. January 2007 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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Oxidative stress, impaired calcium homeostasis and nitric oxide production in the heart of rats in chronic and intermittent hypoxiaYeung, Hang-mee., 楊恆美. January 2009 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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Effects of green tea on bone loss in mature ovariectomized rat容冠宇, Yung, Koon-yu, Samuel. January 2001 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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The effect of nicotine on liver functions in rats and its modulation of the hepatotoxicity induced by carbon tetrachlorideGogo, Arturo R. January 1992 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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