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Mechanisms of the adverse actions of cigarette smoking on gastric ulcer formation and its healing in the ratMa, Li, 馬莉 January 1998 (has links)
published_or_final_version / Pharmacology / Doctoral / Doctor of Philosophy
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Adrenomedullin: its peptide levels and gene expression in the rat, their changes in spontaneous and renovascularhypertensionHwang, Shui-shan, Isabel., 黃水珊. January 2001 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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A study of changes in the blood volume and in certain blood componentsduring cold adaptation in the rat王士孚, Wang, Shih-fu. January 1973 (has links)
published_or_final_version / Physiology / Master / Master of Philosophy
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Investigation of the control of major enzymes involved in adenosine metabolism in rat skeletal muscleCheng, Bo, 程菠 January 1998 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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Postnatal development of otolith neurons in the vestibular nucleus of rats黎振航, Lai, Chun-hong. January 1999 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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Synaptic modulation by 5-hydroxytryptamine in the rat hypothalamic paraventricular nucleusHo, Sze-ngar, Sara., 何思雅. January 2005 (has links)
published_or_final_version / abstract / Zoology / Master / Master of Philosophy
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Protective effects of melatonin on hippocampal and vascular injuries induced by chronic and intermittent hypoxia in ratsHung, Ming-wai., 洪明偉. January 2008 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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Role of neuropeptide Y and its receptor analogues in focal cerebral ischemia in the ratChen, Shaohua, 陳韶華 January 2002 (has links)
published_or_final_version / Medicine / Doctoral / Doctor of Philosophy
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The influence of chronic hypoxia on the responses to endothelin of thepulmonary circulation of ratsDas, Rapti. January 2001 (has links)
published_or_final_version / Physiology / Doctoral / Doctor of Philosophy
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LIPID DIGESTION AND ABSORPTION IN THE SUCKLING RAT.STAGGERS, JOAN ELIZABETH. January 1983 (has links)
The suckling rat has provided a useful model for these studies of lipid digestion and absorption. In adults dietary triacylglycerols are predominantly hydrolyzed by the "classic" mechanism involving pancreatic lipase (E.C. 3.1.1.3) and biliary micelle-mediated product uptake. Unlike affluent man, adult laboratory rats normally consume a low-fat diet (< 20% of energy). However suckling rats, like most neonates, consume a milk diet that is normally high in fat. Suckling rats receive ~90% of non-protein energy from milk triacylglycerols, although rats have very low levels of "classic" pancreatic lipase before weaning. Dissertation studies demonstrate that other lipases promote efficient gastrointestinal triacylglycerol utilization in suckling rats. Nearly half of milk triacylglycerols are hydrolyzed to diacylglycerol within the stomach; and results strongly support that lingual lipase is the significant source of this activity. Furthermore, enzyme studies show considerable similarity between this lipase from rat tongue and so-called pregastric esterases of suckling ruminant species. Of fatty acids released in stomach, nearly three-quarters are of medium-chain length. These have high aqueous solubility and are rapidly absorbed from the upper gastrointestinal tract. Remaining triacylglycerols, diacylglycerols, and long-chain fatty acids enter the intestinal lumen and mix with lipid-rich bile. Suckling rats have higher biliary concentrations of bile salts, phospholipids and cholesterol than do adults. Bile salt enterohepatic circulation clearly occurs in the suckling rat, at least as early as 10 days. The bile acid β-muricholate is elevated during the suckling period, compared to post-weaning. Results show that further lipolysis occurs along the intestine, possibly through the action of lingual lipase and others from pancreas, producing mostly long-chain free fatty acids, monoacylglycerol, and some lysophosphatidylcholine, derived largely from bile. This composition closely resembles adult intestinal contents, but is much higher in both dietary and biliary lipid constituents. Alteration of milk triacylglycerol fatty acids produced no apparent impairment in gastrointestinal lipid utilization by sucklings, but resulted in hyperlipemia and increased carcass fatness. These results suggest gastrointestinal events do not limit triacylglycerol utilization in the suckling rat, regardless of composition; but post-absorptive metabolism may be different when sucklings consume altered milk lipids.
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