This study investigated whether lutein and DHA enriched egg consumption can improve electrophysiological retina function for the prevention of age-related macular degeneration in Caucasian older adults. Thirty (male: n=11, female: n=19) healthy Caucasian older adults (64.0 ± 3.4 years) consumed two lutein and DHA enriched eggs (0.87 mg lutein/day, 220 mg DHA/day) daily for six weeks. Retina function, plasma and red blood cell (RBC) DHA, plasma lutein, lipid profiles, and lipoprotein subfractions were assessed at day 0 and 6 wks. The maximum amplitude of scotopic a-wave and photopic b-wave significantly increased along with plasma DHA concentrations No significant alterations in plasma Chol, HDL-Chol, LDL-Chol, triacylglycerides, plasma lutein and RBC DHA were present. A significant increase in large HDL particles and a decrease in intermediate sized HDL particles occurred. This study suggests that consuming two lutein and DHA enriched eggs daily may improve electrophysiological retina function without adversely altering plasma lipids in Caucasian older adults. / May 2017