MENVSC / Department of Geography and Geo-Information Sciences / Road transport safety is challenging globally, especially in developing countries, where it affects both road users and governments. The aim of road traffic safety is to ensure a reduction or total eradication of road fatalities and other injuries that are related to road accidents resulting from public road usage. In South Africa, one of the major problems faced by the Department of Roads and Transport is the issue of road traffic accidents. Between 2004 and 2010 the annual road traffic accidents increased to over 500,000 and 28,000 or more are fatal, which has led to serious injuries, as reported by the Department. This study analysed patterns and trends of road traffic injuries and fatalities in Vhembe District Municipality from January 2011 to August 2015. It also mapped road accident hotpots using Getis hotspot analysis and linear referencing in ArcGIS 10.2 spatial statistics extension. The research further established correlation between accidents spots and road design geometry. Factors that are responsible for road traffic accidents leading to fatalities, injuries, and loss of property were also examined. Pedestrian behavioural attitude towards adhering to road safety measures was studied using systematic random sampling, field observation and questionnaires. Finally, the study investigated if there has been any significant reduction in the road traffic injuries and fatalities occurrence rate within the last five years in Vhembe District since the commencement of World Health Organisation; Decade of Action for Road Safety 2011-2020. It was found out that most of the accidents occurred as a result of changes in human social behaviour, negligence and indulgence. The passenger road users category is the worst affected followed by drivers and pedestrians. It was found out that road crashes have decreased by 35% since the commencement of decade of action for road safety. The composition of road traffic injuries and fatalities since 2011 shows a reduction in the numbers of victims recorded. An average of 86 fatalities, 326 serious injuries and 701 minor injuries occurred per annum within the study period. There was high significant value (p  0.05) among all the categories of road users understudied. The differences observed were real and did not occurred by chance for the 5year period (2011 – 2015).