Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos y artículos preprint actualizados al 08 de Junio de 2020.

The SARS-CoV-2 pandemic is not only a health crisis, but also shatters the socialand economic lives through regulations and social restrictions. As seen duringSARS 2002-2003, measures like social restrictions can impact behaviournegatively, leading to discrimination, stigmatisation and xenophobia. There is alack of studies on antisocial behaviour and crime during health crises, such aspandemics. Related studies on disaster and crime gave mixed results, with somesuggesting an increase in prosocial rather than antisocial behaviour. Using acriminological perspective, German news media from January 1, 2020 untilMarch 31, 2020 were analysed. These media sources were the tabloid Bild andtwo main elite newspapers, Süddeutsche Zeitung and Frankfurter AllgemeineZeitung. Analyses were conducted quantitatively based on frequencies, means andword counts. Additionally, a qualitative media content analysis regarding events,behaviour and story tone was undertaken. The aim was to reveal indications ofreported behavioural changes. For a complete overview, both antisocial andprosocial behaviours were included. Results indicate that antisocial behaviour,such as ignoring of governmental advice and rules, and discriminatory behaviours,as well as crimes like fraud became more prominent over time than prosocial andhelping behaviour. This study shows only a fragment of the situation in Germany,but highlights the importance of continuous assessments of human behaviourduring dynamic and critical times.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos, documentos técnicos y artículos en preprint actualizado al 22 de Abril de 2020.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos, artículos en preprint y noticias científicas actualizado al 23 de Abril de 2020.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos, artículos en preprint y revisiones sistemáticas actualizado al 24 de Abril de 2020.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos, revisiones sistemáticas y noticias científicas actualizado al 27 de Abril de 2020.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos y artículos preprint actualizados al 01 de Junio de 2020.

Boletín que incluye información científica sobre el COVID-19, incluye artículos científicos y artículos preprint actualizados al 02 de Junio de 2020.

Foreign direct investment has been sharply affected by the global SARS-CoV-19 pandemic, as quarantine measures have decimated global trade, aviation and domestic economies through lockdowns which have wreaked havoc on markets. Macroeconomic indicators including GDP growth rates, unemployment, business confidence, consumer confidence, retail sales and inflation have all been negatively affected due to the simultaneous supply & demand shock caused by the pandemic. Economic crises are a regularly occurring feature, with a degree of cyclicality determining their emergence. The uniqueness of crises, in their appearance and dissipation, stems from a large variance in relevant macroeconomic, fundamental and societal factors giving rise to the crisis in the first place, with the uniqueness being bound and pertinent to a selected period of time in history under which they occurred. In this thesis we explored the impact of the two most significant economic crises of the 21st century, the Great Recession and the ongoing SARS-CoV-19 pandemic and their impact on capital flows, specifically on FDI-flows in two developed markets and two emerging markets. Our findings suggest that FDI-flows display a high synchronicity with stages of economic cycles, and tend to decrease during economic recessions and increase during economic expansions.

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. / SARS-CoV-2 main protease is a common target for inhibition assays due to its high conservation among coronaviruses. Since flavonoids show antiviral activity, several in silico works have proposed them as potential SARS-CoV-2 main protease inhibitors. Nonetheless, there is reason to doubt certain results given the lack of consideration for flavonoid promiscuity or main protease plasticity, usage of short library sizes, absence of control molecules and/or the limitation of the methodology to a single target site. Here, we report a virtual screening study where dorsilurin E, euchrenone a11, sanggenol O and CHEMBL2171598 are proposed to inhibit main protease through different pathways. Remarkably, novel structural mechanisms were observed after sanggenol O and CHEMBL2171598 bound to experimentally proven allosteric sites. The former drastically affected the active site, while the latter triggered a hinge movement which has been previously reported for an inactive SARS-CoV main protease mutant. The use of a curated database of 4.8 k flavonoids, combining two well-known docking software (AutoDock Vina and AutoDock4.2), molecular dynamics and MMPBSA, guaranteed an adequate analysis and robust interpretation. These criteria can be considered for future screening campaigns against SARS-CoV-2 main protease. / Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica / Revisión por pares