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Tese de mestrado integrado. Engenharia Industrial e Gestão. Faculdade de Engenharia. Universidade do Porto. 2011

Der Vortrag stellt zwei Filesysteme aus der kommerziellen Welt vor die derzeit auf Linux portiert werden: JFS von IBM und XFS von SGI. Es wird ein Ueberblick ueber die beiden Dateissysteme, ihre Eigenschaften und ihre Portiertung gegeben.

Made available in DSpace on 2016-04-25T19:20:30Z (GMT). No. of bitstreams: 1 Mitiyo Santiago Murayama.pdf: 1685422 bytes, checksum: d82245636d489108b87f0c70b67678b0 (MD5) Previous issue date: 2014-02-17 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / The scope of this research is to make an attentive reading of the official proselytize speech from the lay Buddhist organization Brasil Soka Gakkai Internacional (BSGI), which is published in several journals, contextualizing it according the two sociological conversion paradigms: classic and contemporary. These paradigms are built upon three main axis concerning time, intensity and social networking of the convert. According the classic paradigm, the conversion occurs suddenly and unexpectedly; it is very intense, since the individual is supposed to go through a deep and totalizing transformation in this decision-making moment. Also, it is a completely solitary and autonomic way, without any influence of others. The new paradigm, the contemporary one, shows conversion as a long-term process, where the convert interacts with their social context, presenting itself as an alternative for the classic paradigm of the religious conversion / Esta pesquisa tem como objetivo fazer uma leitura do discurso proselitista oficial da organização leiga budista Associação Brasil Soka Gakkai Internacional publicado em seus diversos periódicos e contextualizá-lo segundo os dois paradigmas sociológicos da conversão religiosa, o clássico e o novo. Esses paradigmas estão relacionados em torno de três eixos principais relativos ao tempo, à intensidade e à rede social do convertido. Segundo o paradigma clássico, a conversão acontece de forma súbita, num momento repentino; caracteriza-se por ser muito intensa, já que o indivíduo passa por uma profunda e totalizante transformação nesse momento decisório; e ocorre de maneira solitária, sem a influência nem a participação de outros. O paradigma novo mostra a conversão como um processo que pode durar anos e é permeado por um diálogo do convertido com seu contexto social, apresentando-se dessa forma como uma alternativa para o paradigma clássico da conversão religiosa

International Telemetering Conference Proceedings / October 25-28, 1999 / Riviera Hotel and Convention Center, Las Vegas, Nevada / The NASA GSFC’s Wallops Flight Facility’s (WFF) Mobile Range Control System (MRCS) is based on the functionality of the WFF Range Control Center at Wallops Island, Virginia. The MRCS provides real time instantaneous impact predictions, real time flight performance data, and other critical information needed by mission and range safety personnel in support of range operations at remote launch sites. The MRCS integrates a PC telemetry processing system (TELPro), a PC radar processing system (PCDQS), multiple Silicon Graphics display workstations (IRIS), and communication links within a mobile van for worldwide support of orbital, suborbital, and aircraft missions. This paper describes the MRCS configuration; the TELPro’s capability to provide single/dual telemetry tracking and vehicle state data processing; the PCDQS’ capability to provide real time positional data and instantaneous impact prediction for up to 8 data sources; and the IRIS’ user interface for setup/display options. With portability, PC-based data processing, high resolution graphics, and flexible multiple source support, the MRCS system is proving to be responsive to the ever-changing needs of a variety of increasingly complex missions.

While distributed memory systems have shaped the field of distributed systems for decades, the demand for many-core shared memory resources is increasing. Symmetric Multiprocessor Systems (SMPs) have become increasingly important recently among a wide array of disciplines, ranging from Bioinformatics to astrophysics, and beyond. With the increase in big data computing, the size and scope of traditional commodity server systems is often outpaced. While some big data applications can be mapped to distributed memory systems found through many cluster and cloud technologies today, this effort represents a large barrier of entry that some projects cannot cross. Shared memory SMP systems look to effectively and efficiently fill this niche within distributed systems by providing high throughput and performance with minimized development effort, as the computing environment often represents what many researchers are already familiar with. In this paper, we look at the use of two common shared memory systems, the ScaleMP vSMP virtualized SMP deployment at Indiana University, and the SGI UV architecture deployed at University of Arizona. While both systems are notably different in their design, their potential impact on computing is remarkably similar. As such, we look to compare each system first under a set of OpenMP threaded benchmarks via the SPEC group, and to follow up with our experience using each machine for Trinity de-novo assembly. We find both SMP systems are well suited to support various big data applications, with the newer vSMP deployment often slightly faster; however, certain caveats and performance considerations are necessary when considering such SMP systems.

Made available in DSpace on 2016-04-28T20:16:27Z (GMT). No. of bitstreams: 1 2008 - Fabio Silva de Souza.pdf: 3760278 bytes, checksum: d38f28c39076f3f01e4393fd0f31bc10 (MD5) Previous issue date: 2008-11-26 / The aim of this study was to characterize the association between the seasonality of dermatobiosis in bovines and its dipterans potential vectors as well as evaluate the association among the counts of Dermatobia hominis larvae and of potential vectors with meteorologicals data. It also had the objective of delimiting, quantifying and characterizing the geographical space of Serop?dica and Itagua? municipalities in relation to the favorable degrees for the occurrence of dermatobiosis in bovines in the rainy and dry periods using the Vista SAGA? 2007 information system. The seasonal fluctuation of D. hominis larvae was obtained by counts in ten bovines and of muscoids dipterans by capture using Adultrap? traps with sardine bait, once a month each, in three properties named A, B and C, localized in the Serop?dica, Paracambi and Itagua? municipalities, respectively, in the period of January 2006 to December 2007. The meteorological data of compensated mean temperature, pluvial precipitation and relative humidity were obtained in the Agricultural Ecology Station (22?48'S, 43?41'W and 33m of altitude). The associations between D. hominis larvae fluctuations, adult dipterans and climatological data were verified using the Spearman correlation test. Kruskal-Wallis and Mann-Whitney tests were used in the analysis of the significant differences between the rainy and dry periods in each property in the monthly average of D. hominis larvae, in the total monthly number and of dipterans family and in the analysis of other studies. In the elaboration of models by geoprocessing, some abiotic factors were used: occupation and covering of the land, altitude, declivity, soils and climatic factors, in which the evaluation, signature and monitorship functions of the Vista SAGA? 2007 program were applied. The infestation by D. hominis larvae in bovines was present during the 24 months of study in the three properties. A total of 18.966 dipterans potential vectors was captured, being 30,16% in the A property, 34,59% in the B property and 35,25% in the C property but there were no significant statistic difference between these. There was a positive and significant correlation (rs=0,63) between monthly averages of D. hominis larvae and relative humidity in 2006 at the A property; there was a positive and significant correlation between the total number of captured dipterans and pluvial precipitation (rs=0,80) and temperature (rs=0,60) at the B and C properties, respectively, in 2007. It was also observed a positive and significant correlation between the total number of captured dipterans of the Sarcophagidae family (rs=0,60) with the temperature in the C property in 2006, and between Muscidae (rs=0,67) and Calliphoridae (rs=0,76) with pluvial precipitation in the B property in 2007. There wasn t an association between monthly averages of D. hominis larvae and dipterans. It was verified a pattern lack in the association between monthly and periods fluctuations, rainy and dry of D. hominis larvae with the dipterans potential vectors fluctuations and of both with meteorologicals data. The geoprocessing allowed delimiting, quantifying and characterizing the potential of space temporal distribution of dermatobiosis in bovines. / Este estudo teve como objetivos caracterizar a associa??o entre a sazonalidade da dermatobiose em bovinos e seus d?pteros potenciais vetores, assim como avaliar a associa??o entre as contagens de larvas de Dermatobia hominis e de potenciais vetores com os dados meteorol?gicos. Teve tamb?m como objetivo, delimitar, quantificar e caracterizar o espa?o geogr?fico dos munic?pios de Serop?dica e Itagua? quanto aos gradientes de favorabilidade para a ocorr?ncia da dermatobiose em bovinos nos per?odos chuvoso e seco utilizando o sistema de informa??o Vista SAGA? 2007. A flutua??o sazonal de larvas de D. hominis foi obtida por contagens em dez bovinos e a de d?pteros musc?ides por captura, usando armadilhas Adultrap? com isca de sardinha, ambos uma vez ao m?s, nas tr?s propriedades denominadas A, B e C, localizadas nos munic?pios de Serop?dica, Paracambi e Itagua?, respectivamente, no per?odo de janeiro de 2006 a dezembro de 2007. Os dados meteorol?gicos de temperatura m?dia compensada, precipita??o pluvial e umidade relativa, foram obtidos na Esta??o Ecologia Agr?cola (22?48'S, 43?41'W e 33m de altitude). As associa??es entre as flutua??es de larvas de D. hominis, d?pteros adultos e dados climatol?gicos foram verificadas utilizando-se o teste de correla??o de Spearman. Os testes de Kruskal-Wallis e Mann-Whitney foram empregados na an?lise das diferen?as significativas entre os per?odos, chuvoso e seco, por propriedade, para a m?dia mensal de larvas de D. hominis, o n?mero mensal total e por fam?lia de d?pteros e na an?lise de dados publicados em outros estudos. Para a elabora??o dos modelos por geoprocessamento, utilizaram-se os fatores abi?ticos: uso e cobertura das terras, altitude, declividade, solos e fatores clim?ticos, aplicando-se as fun??es avalia??o, assinatura e monitoria do programa Vista SAGA? 2007. A infesta??o por larvas de D. hominis em bovinos esteve presente ao longo dos 24 meses de estudo nas tr?s propriedades. Um total de 18.966 d?pteros potenciais vetores foi capturado. Deste, 30,16% foram capturados na propriedade A, 34,59% na propriedade B e 35,25% na propriedade C, mas sem diferen?a estat?stica significativa entre estas. Houve correla??o positiva e significativa (rs=0,63) entre as m?dias mensais de larvas de D. hominis e umidade relativa, no ano de 2006, na propriedade A; houve correla??o positiva e significativa entre o n?mero total de d?pteros capturados e precipita??o pluvial (rs=0,80) e tamb?m com a temperatura (rs=0,60) nas propriedades B e C, respectivamente, no ano de 2007. Observou-se tamb?m correla??o positiva e significativa entre o n?mero total de d?pteros capturados da fam?lia Sarcophagidae (rs=0,60) com a temperatura na propriedade C no ano de 2006 e entre Muscidae (rs=0,67) e Calliphoridae (rs=0,76) com precipita??o pluvial na propriedade B em 2007. N?o ocorreu associa??o entre as m?dias mensais de larvas de D. hominis e de d?pteros. Constatou-se uma falta de padr?o na associa??o entre as flutua??es mensais e por per?odos, chuvoso e seco, das larvas de D. hominis com as flutua??es de d?pteros potenciais vetores e de ambas com os dados meteorol?gicos. O geoprocessamento permitiu delimitar, quantificar e caracterizar o potencial de distribui??o espa?o-temporal da dermatobiose nos per?odos chuvoso e seco.

Antagonism of the activin receptor signaling pathway represents a promising potential therapy for the muscular dystrophies and other muscle wasting disorders (i.e., cachexia or sarcopenia). Previous research has shown that antagonism of activin signaling promotes muscle growth, attenuates muscle wasting, and restores function in both wild type and diseased animals. Our laboratory has recently developed a novel small molecule (SGI-1252) that inhibits activin downstream (i.e., Smad2/3 phosphorylation) signaling. Purpose: In this study we determined how eight weeks of orally administered SGI-1252 affected TGF-ß signaling, whole body mass, individual limb muscle mass, and muscle fiber cross sectional area (CSA). Methods: Wild-type (WT) mice were treated with SGI-1252 or a vehicle control (VC) via oral gavage (400 mg/kg 3 times per week) for 8 weeks. Body mass was measured twice per week during the 8-week treatment period. At the end of the treatment period, gastrocnemius and tibialis anterior (TA) muscles were excised, weighed, and prepared for histological and biochemical analyses. Results: Following 8 weeks of treatment, there was no difference in weight gain between SGI-1252 (24.8 ± 1.8g) and VC treated mice (23.2 ± 1.5g) (p = 0.06). Gastrocnemius whole muscle mass was significantly greater in the SGI-1252 treated group relative to the VC treated mice (139.6 ± 12.8 mg vs 128.8 ± 14.9 mg) (p = 0.04), although when normalized with body mass there was no difference in gastrocnemius mass. For the TA muscle, there were no significant differences in whole muscle mass between SGI-1252 and VC groups, yet TA muscles in the SGI-1252 treated group had a reduced muscle fiber CSA compared to controls (621 ± 44 µm2 vs 749 ± 36 µm2) (p = 0.0005). There was a statistical trend of decreasing Smad2 phosphorylation in the SGI-1252 treated TA muscles (mean SGI-1252 = 0.668 vs VC = 0.848) (p = 0.06), and no significant differences in Smad2 phosphorylation in the gastrocnemius. Conclusions: Contrary to our hypothesis, 8 weeks of orally administered SGI-1252 was not effective in promoting increases in whole body mass, limb whole muscle mass, or myofiber cross sectional area. This may be due to the inability of SGI-1252, at the administered dose, to effectively decrease signaling downstream of the activin receptor. Clearly, studies using a wider range of doses and delivery methods will be needed to ascertain the efficacy of SGI-1252 as a potential therapeutic.

Der Vortrag stellt zwei Filesysteme aus der kommerziellen Welt vor die derzeit auf Linux portiert werden: JFS von IBM und XFS von SGI. Es wird ein Ueberblick ueber die beiden Dateissysteme, ihre Eigenschaften und ihre Portiertung gegeben.

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