No description available.

Thesis (Ph. D.)--University of Wisconsin--Madison, 1964. / Typescript. Abstracted in Dissertation abstracts, v. 25 (1964) no. 6, p. 3525. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (M.S.)--University of Wisconsin--Madison, 1963. / Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 132-134).

Previous in vitro studies have shown that shark cartilage extracts stimulate human leukocytes to release significant levels of TNFα, a cytokine typical of a Th1 immune response. The purpose of this study was to investigate further the effects of shark cartilage on cellular immune function, particularly cell proliferation, apoptosis, and IL-4 and INFγ production. The viability and proliferation of cell cultures grown in the presence of shark cartilage extract was not significantly different from unstimulated control cultures or those stimulated with mitogens (Con A, PMA, LPS), respectively. The effect of shark cartilage on apoptosis was determined by microscopic analysis of morphological apoptotic changes and by the detection of DNA fragmentation observed as characteristic ladder formation in agarose gel electrophoresis. While DNA fragmentation could not be demonstrated for cartilage-stimulated cells, characteristic morphological changes, indicative of apoptosis, were observed in leukocytes following incubation with shark cartilage extract. A statistically significant difference was not noted in the number of apoptotic cells present in cartilage-stimulated leukocytes and those stimulated with 0.5 μM/ml of staurosporine, suggesting that apoptosis is induced in the presence of cartilage extract. Culture supernatants of cartilage-stimulated leukocytes were assayed for IL-4 and IFN-γ by enzyme-linked immunosorbent assay (ELISA). Although a low level of IL-4 and INFγ was detected in culture supernatants of Con A and PMA stimulated cells it was not significantly different from that of unstimulated control cultures. Thus the significance of the absence of detectable IL-4 or INFγ in supernatants of cartilage- stimulated cultures could not be determined. However, as previously shown, supernatants did contain TNFα. Results of the study did not show a definitive pattern of cytokine production, characteristic of either a Th1 or Th2 type immune response.

The present study is a content analysis of thirteen speeches presented by Jeane Jordan Kirkpatrick while she served as the United States Permanent Representative to the United Nations from 1981-1985. Seven of the speeches were made before the Security Council, five before the General Assembly, and once before the Economic and Social Council. Kenneth Burke's pentadic analysis provides a highly appropriate methodology through which to view Kirkpatrick's United Nations speeches. It assumes the existence and use of written texts. The dramatistic metaphor, which constitutes the basis of Burke's critical model, is widely used by political scientists and sociologists, as well as by rhetorical critics. The pentad serves as an organizing scheme to understand, explain, and to evaluate what speakers do and why they do it. The analyses indicate that Kirkpatrick associates most often with a pragmatic line of argument, incorporating a conservative view of the world. This is revealed through her frequent use of Burke's act-agency and agent-agency ratios. She weaves examples of proven occurrences throughout her rhetoric to support her conservative stance on most issues addressed during this period. In addition, the analysis reveal that Kirkpatrick's motive for speaking is to show support for United States allies, in particular, Israel. The appendix includes data from a DICTION analysis of three of Kirkpatrick's speeches. These results are inconclusive. This study serves as a base from which to branch out to continue further research on Kirkpatrick, other women speakers and other Permanent Representatives. In addition, the study can serve as a spring board for a comparison of political speakers in general.

Thesis--Lund. / Includes bibliographical references (p. 236-246).

This investigation grew out of my experiences while working as a mental nurse with people deemed to be insane. The behaviours which they presented and the medical and legal control exercised over them became of concern to me because I felt their rights were not being respected. A primary issue is the extent to which adherence to the medical-somatic view of insanity held by psychiatrists, lawyers and politicians has led to the exclusion of viable custody and treatment alternatives. The purpose of this research is to question the role and functions of mental nurses. It suggests that 'caretakers' might be a more suitable title for such workers with the insane. The hypothesis underlying the research links the work of 'caretakers' of the insane to changes in government policies and legislation; the thesis examines this hypothesis in the light of changes in the roles and functions of 'caretakers' over the period from 1890 to 1990. Research activities included the examination of primary sources, Hansard, newspapers, and professional journals. Interviews were also carried out with nine contemporary caretakers who have worked with the 1959 and the 1983 Mental Health Acts. These research methods provided an historical background to the debates in the Houses of Parliament when mental health legislation was discussed; information from the writings of the professionals who worked with the insane at the times of new mental health legislation; data on the public and media debate of these issues; and information on the perceptions and duties of caretakers working with the insane at the times of new mental health legislation. The research findings show that both those who cared for the insane and the insane themselves have been subjected to changes brought about by mental health legislation since 1890. These changes affected the working conditions of the caretakers and the social control and rights of the insane. The changes in the work of caretakers led to new directions in their education. Workers with the insane became a part of nursing by adopting the somatic approach to care. When this occurred, many of the care activities of keepers, attendants and mental nurses became redundant. Over time, there has been a move to, and then away from, the clinical-somatic model of nursing towards caretaking skills such as group work, therapeutic community skills, counselling skills and psychotherapy skills. These caretaking skills are seen by contemporary caretakers as going beyond their custodial and social control functions, towards providing a space in which people can be respected, encouraged, supported and be open to new insights.

No description available.

"The purpose of this study is to compile useful information regarding the merits of a specific kind of multi-level reading program. Another purpose in this study is to ascertain, insofar as is possible, the reaction of both educators and students to such a program. The scope of the study encompasses two major areas: (1) an historical approach, consisting of a review of the literature in the entire field of multi-level reading materials, (2) an evaluation, through the use of an opinionnaire, which was sent to Florida educators who have used the materials"--Introduction. / Typescript. / "June, 1961." / "Submitted to the Graduate Council of Florida State University in partial fulfillment of the requirements for the degree of Master of Science." / Advisor: Mildred Swearingen, Professor Directing Study. / Includes bibliographical references (leaves 51-53).

Critical values are laboratory values that represent a life-threatening condition for which there is a treatment available. Laboratories make immediate notifications to ordering providers when critical values are identified so that they may quickly act to initiate a treatment for their patient. The majority of laboratories apply the inpatient critical value list to the outpatient setting, although there are many differences between an acutely ill inpatient population and an ambulatory outpatient population. The goal of this study was to determine if providers responded to the critical values in the outpatient setting and to determine if there was a difference in outcome indicators when providers responded to notifications and when they did not respond to notifications. Data for 673 critical value notifications for PT/INR, Digoxin, and Glucose results were collected from Riverside Health System’s five laboratories. Analysis suggested that the inpatient critical value lists and thresholds may not be appropriate to apply to the outpatient setting. In this study of 637 critical value notifications, providers chose not to respond to 25.7% of critical value notifications. Providers were more likely to respond to PT/INR and Digoxin critical value notifications that glucose critical value notifications. None of the cases for either of the three tests that went without a provider response resulted in death or serious harm to a patient, indicating that the critical value thresholds do not meet the definition of a critical value in the outpatient setting. In the future, laboratories should explore the utilization of a different critical value list and thresholds for the outpatient setting based upon patient outcomes.