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Scale analysis of the diurnal cycle of precipitation over Continental United StatesBorque, Paloma January 2011 (has links)
No description available.
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Meteorological analysis and historical perspective of the 1999-2005 Canadian Prairie droughtHryciw, Lisa January 2010 (has links)
No description available.
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Development of a coupled blowing snow-atmospheric model and its applicationsYang, Jing January 2010 (has links)
No description available.
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Carbon and water vapour exchange in a temperate fresh water marshCrombie, Stephanie January 2013 (has links)
No description available.
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The response of the width of the Hadley cell to global warming-like thermal forcing in a simple general circulation modelLin, Nai Shi January 2011 (has links)
No description available.
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Synoptic analysis of cold-season surface wind regimes in MontrealRazy, Alissa January 2010 (has links)
No description available.
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A new one-year global lagrangian climatology of mass transport in the lowermost stratospherePaull, Georgina January 2013 (has links)
No description available.
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An establishment of an objective dynamical framework for forecast model evaluation of extratropical transitionsSpassiani, Alessio January 2015 (has links)
No description available.
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Development and Validation of a Liquid Chromatography-Mass Spectrometry Assay for Determination of Cromolyn Sodium in Skin Permeation StudiesHolman, Miranda K., Brown, Stacy D., Frempong, Dorcas, Puri, Ashana, Dinh, Steven 01 January 2022 (has links)
Cromolyn sodium (CS) is a mast cell stabilizer administered to treat allergic diseases. A topical system would sustain its delivery and may be designed for treatment of atopic dermatitis. Established HPLC protocols for detection of CS are time consuming and intensive, indicating the need for a more streamlined method. This study aimed at developing and validating a sensitive and selective LC-MS method for quantifying CS in skin permeation studies that was less time and resource demanding. The optimized method involved an isocratic mobile phase (10 mM NHHCO, pH 8.0, 90% and ACN, 10%) at a flow rate of 0.25 mL/min. Detection involved direct MS/MS channels with m/z 467.0255 (precursor) and / 379.0517 (fragment) using argon as the collision gas. CS calibrants were prepared in PBS, pH 7.4, and methanol for validation (0.1-2.5 g/mL). To ensure no skin interference, dermatomed porcine skin was mounted on Franz diffusion cells that were analyzed after 24 h. The skin layers were also separated, extracted in methanol, and analyzed using the developed method. Retention time was 1.9 min and 4.1 min in methanol and buffer, respectively. No interfering peaks were observed from the receptor and skin extracts, and linearity was established between 0.1 and 2.5 g/mL. Interday and intraday accuracy and precision were within the acceptable limit of ±20% at the LLOQ and ±15% at other concentrations. Overall, the simplified, validated method showed sensitivity in detecting CS in skin without interference and was applied to demonstrate quantification of drug in skin following 4% cromolyn sodium gel exposure.
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Major cold-season precipitation events at Iqaluit, NunavutGascon, Gabrielle January 2008 (has links)
No description available.
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