Thesis--University of Colorado. / Includes bibliographical references. Also issued in print.

Thesis--University of Colorado. / Includes bibliographical references.

Thesis (Ph.D.)--University of Tennessee Health Science Center, 2009. / Title from title page screen (viewed on July 22, 2009). Research advisor: Edwards A. Park. Document formatted into pages (xi, 94 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 69-89).

Thesis (M.S.)--University of Tennessee Health Science Center, 2009. / Title from title page screen (viewed on July 29, 2009 ). Research advisor: Stephen White. Document formatted into pages (vii, 47 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 41-46).

Thesis (Ph.D.)--University of Tennessee Health Science Center, 2007. / Title from title page screen (viewed on February 29, 2008). Research advisor: Robert S. Waters, Ph.D. Document formatted into pages (xix, 179 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 152-178).

Thesis (Ph.D. )--University of Tennessee Health Science Center, 2007. / Title from title page screen (viewed on May 16, 2008 ). Research advisor: Gerald I. Byrne, Ph.D. Document formatted into pages (xi, 114 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 65-107).

Thesis (Ph.D.)--University of Tennessee Health Science Center, 2007. / Title from title page screen (viewed on July 28, 2008). Research advisor: Gerard P. Zambetti, Ph.D. Document formatted into pages (xvi, 134 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 104-126).

Thesis (Ph.D.) -- Memorial University of Newfoundland. / Typescript. Bibliography: leaves 446-492. Also available online.

In 2007, juveniles were involved in a minimum of 1,063 murders in the United States (Federal Bureau of Investigation, 2008), and a concern over juvenile homicide offenders remains. While increasingly more macrolevel research on juvenile homicide offending has been accumulated, particularly since the 1980s, research focusing on macrolevel correlates of juvenile homicides is still relatively scarce (MacDonald & Gover, 2005; Ousey & Campbell Augustine, 2001). In the first part of this study, several variables relating to the offender, victim, setting, and precursors to the homicide by race and gender were examined in order to provide details on the context of youth homicides between 1965 and 1995 in Chicago. The Homicides in Chicago, 1965-1995 data set and Census data for 1970, 1980, and 1990 were used in this study. The results indicate that changes in youth homicides over the 31-year time period involved increases in lethal gang altercations, particularly among Latinos, and increases in the use of automatic weapons. Young females had very little impact on homicide rates in Chicago. The second part of the study examined whether measures of social disorganization can aid in the prediction of homicides committed by youths, and a total of ten negative binomial models were run. The results of the analyses in the three time periods indicate that racial/ethnic heterogeneity, educational deprivation, unemployment, and family disruption are significantly and positively related to homicides. Foreign-born population and median household income were found to be significantly and negatively related to homicides. The significant indicators of social disorganization varied in the seven models for the disaggregated groups. Overall, the results reflect support for social disorganization theory. Limitations, suggestion for future research, and policy implications are also addressed.

Thesis (D.Tech.: Clinical Technology)-Durban Institute of Technology, 2005 xxiv, 235 leaves ; ill. ; 30 cm / Fumonisin B1 (FB1) and ochratoxin A (OTA) represent examples of mycotoxins of greatest public health and agro-economic significance. They ex¬ert adverse effects on humans, animals and crops that result in illnesses and economic losses. Fumonisin B1 are cancer-promoting metabo¬lites of Fusarium proliferatum and F verticillioides, (formerly moniliforme), and are implicated in oesophageal cancer. Ochratoxins are metabolites of both Aspergillus and Penicillium species. These compounds are known for their nephrotoxic effects in all animal species and may promote tumours in humans. In man OTA exhibits unusual toxicokinetics, with a half-life in blood of 840 h (35 days) after oral ingestion. Although much is known regarding the toxicology of these toxins, little is known of the effects of these toxins on the immune system. The aim of this study was to determine and compare the immunomodulating effects of FB1 and OTA in human carcinoma. Initial experiments involved isolating lymphocytes and neutrophils from healthy volunteers. The isolated cells were exposed to either FB1 or OTA on a dose and time dependent level and LD50 of the toxins was determined. Thereafter, challenge tests were performed, whereby lymphocytes and neutrophils isolated from volunteers, oesophageal cancer patients and breast cancer patients were exposed to the LD50 dose of either FB1 or OTA for the appropriate time. The effect of the toxins was demonstrated by viability studies, light microscopy and electron microscopy. Cytokine receptors (CK, TNF and CSF) were evaluated by immuno-cytochemical methods and the levels of circulating cytokines (IL –1, IL-6, IL-8, IL-10 and TNF-) were determined using ELISA kits.