Dose assessments produced using the computer code MCNP are important to simulate events that are difficult to recreate experimentally. An emergency scenario involving whole-body skin contamination is one example of such an event. For these scenarios, an anthropomorphic phantom of a 10-year-old male with uniform skin contamination was created and combined with MCNP for dose calculations. Activity on the skin was modeled with gamma-ray sources at energies of 50 keV, 100 keV, 250 keV, 500 keV, 750 keV, 1 MeV, 1.25 MeV, 1.5 MeV, and 2 MeV. The radionuclides 60Co, 137Cs, and 131I were also modeled. The effective dose to the body and major organs was calculated for each scenario. Exposure rate contour lines were also produced around the body. The activity required to result in a dose equal to the legal limit of 0.1 mSv for minors was calculated for each scenario. The highest activity required to produce this limit was from the 50 keV gamma-ray source. This activity was increased by an arbitrary value, approximately tenfold the current value, to represent an emergency scenario. This new activity concentration of 1 mCi per 100 cm2 was used to produce doses for each of the scenarios. The lowest effective dose for the body was 0.82 mSv, produced from the 50 keV source. The highest effective dose was 19.59 mSv, produced from the 2 MeV source. The exposure rates nearest the body were approximately 1.25 R/h, decreasing to100 mR/h approximately 60 cm from the body. The data points were found to be dependent on the energy of the gamma ray. These data can also be improved by deriving solutions previously assumed in this scenario. For example, the skin may be broken down into multiple regions to allow for independent calculations for regional contamination. The activity on the skin can also be derived from air concentration models, allowing for the use of other models to be used in conjunction with this research.

This thesis details the measurement and simulation of patient skin doses arising from X-ray exposure during interventional cardiology procedures. Interventional cardiology procedures can be long and complex resulting in high skin doses, to the extent that radiation burns may be produced. Twenty patients were used in the study consisting of 10 coronary angiogram and 10 coronary angioplasty procedures. Radiochromic films were used to measure skin dose directly. The Gafchromic® XR-RV2 film was chosen for its suitability for this project. The key characteristics of this film were experimentally determined including: dose response, energy dependence, polarisation and post-exposure growth. The dose range was found to be ideally suited for the doses encountered in this study. Energy dependence was found to be ~14% between 60 and 125 kVp at 1 Gy and introduced an unavoidable uncertainty into dose calculations from unknown beam energies. Document scanner characteristics were also been investigated and a scanning protocol is determined. A mathematical model was created to use the geometry and exposure information encoded into acquisition files to reconstruct dose and dose distributions. The model requires a set of study files encoded according to the DICOM format, as well as user input for fluoroscopic estimations. The output is a dose map and dose summary. Simulation parameters were varied and results compared with film measurements to provide the most accurate model. From the data collected the relation between dose area product, maximum skin dose and fluoroscopic time were also investigated. The results demonstrated that a model based on acquisition information can accurately predict maximum skin dose and provide useful geometrical information. The model is currently being developed into a standalone program for use by the Medical Physics and Bioengineering department.

A special work evolution was performed at Los Alamos National Laboratory (LANL) with a particular 73As/74As source but the worker’s extremity dosimeter did not appear to provide appropriate dosimetric information for the tasks performed. This prompted a reconstruction of the dose to the worker’s hands. The computer code MCNP was chosen to model the tasks that the worker performed to evaluate the potential nonuniform hand dose distribution. A model was constructed similar to the worker’s hands to represent the performed handling tasks. The model included the thumb, index finger, middle finger, and the palm. The dose was calculated at the 7 mg cm-2 skin depth. To comply with the Code of Federal Regulations, 10 CFR 835, the 100 cm2 area that received the highest dose must be calculated. It could be determined if the dose received by the worker exceeded any regulatory limit. The computer code VARSKIN was also used to provide results to compare with those from MCNP where applicable. The results from the MCNP calculations showed that the dose to the worker’s hands did not exceed the regulatory limit of 0.5 Sv (50 rem). The equivalent nonuniform dose was 0.126 Sv (12.6 rem) to the right hand and 0.082 Sv (8.2 rem) to the left hand.

No description available.

This thesis details the measurement and simulation of patient skin doses arising from X-ray exposure during interventional cardiology procedures. Interventional cardiology procedures can be long and complex resulting in high skin doses, to the extent that radiation burns may be produced. Twenty patients were used in the study consisting of 10 coronary angiogram and 10 coronary angioplasty procedures. Radiochromic films were used to measure skin dose directly. The Gafchromic® XR-RV2 film was chosen for its suitability for this project. The key characteristics of this film were experimentally determined including: dose response, energy dependence, polarisation and post-exposure growth. The dose range was found to be ideally suited for the doses encountered in this study. Energy dependence was found to be ~14% between 60 and 125 kVp at 1 Gy and introduced an unavoidable uncertainty into dose calculations from unknown beam energies. Document scanner characteristics were also been investigated and a scanning protocol is determined. A mathematical model was created to use the geometry and exposure information encoded into acquisition files to reconstruct dose and dose distributions. The model requires a set of study files encoded according to the DICOM format, as well as user input for fluoroscopic estimations. The output is a dose map and dose summary. Simulation parameters were varied and results compared with film measurements to provide the most accurate model. From the data collected the relation between dose area product, maximum skin dose and fluoroscopic time were also investigated. The results demonstrated that a model based on acquisition information can accurately predict maximum skin dose and provide useful geometrical information. The model is currently being developed into a standalone program for use by the Medical Physics and Bioengineering department.

No description available.

京都大学 / 0048 / 新制・課程博士 / 博士(医学) / 甲第22038号 / 医博第4523号 / 新制||医||1038(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 大森 孝一, 教授 松村 由美, 教授 富樫 かおり / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM

<p>Interventional radiological procedures often require long fluoroscopic exposure times and high levels of radiation exposure to patients, which often are higher than most radiological examinations except for computed tomography (CT) whose effective doses can be higher, and in addition to having radiation risks that are higher for both patient and medical staff. Therefore it is important to monitor and map the radiation entrance exposure to the patients, to minimize the probability of skin injury, and to detect areas of overlapping radiation fields. The aim of this thesis is to evaluate patient doses in interventional radiology procedures using a new GAFCHROMIC-XR TYPE R DOSIMETER MEDIA X-ray Dosimetry film, which allows mapping of the skin dose distribution, when placed closer to the skin. These radiochromic films can be characterized by a power response dose function when plotting pixel value versus air kerma and have been calibrated up to 5 Gy when using a flatbed scanner. Image analysis was performed using the red channel component of standard the RGB (Red, Green, and Blue) color space image. The association between the Maximum Entrance Skin Doses (MESD) and Dose Area Product (DAP) values for two interventional procedures; coronary angiography (CA), and percutaneous transluminal coronary angiography (PTCA) is investigated.</p>

Interventional radiological procedures often require long fluoroscopic exposure times and high levels of radiation exposure to patients, which often are higher than most radiological examinations except for computed tomography (CT) whose effective doses can be higher, and in addition to having radiation risks that are higher for both patient and medical staff. Therefore it is important to monitor and map the radiation entrance exposure to the patients, to minimize the probability of skin injury, and to detect areas of overlapping radiation fields. The aim of this thesis is to evaluate patient doses in interventional radiology procedures using a new GAFCHROMIC-XR TYPE R DOSIMETER MEDIA X-ray Dosimetry film, which allows mapping of the skin dose distribution, when placed closer to the skin. These radiochromic films can be characterized by a power response dose function when plotting pixel value versus air kerma and have been calibrated up to 5 Gy when using a flatbed scanner. Image analysis was performed using the red channel component of standard the RGB (Red, Green, and Blue) color space image. The association between the Maximum Entrance Skin Doses (MESD) and Dose Area Product (DAP) values for two interventional procedures; coronary angiography (CA), and percutaneous transluminal coronary angiography (PTCA) is investigated.

During image guided interventional radiology (IR) procedures, acute X-ray induced skin injuries may occur due to high absorbed patient skin dose. These procedures are highly dependent on X-ray imaging both for guiding fluoroscopy and high quality diagnostic image acquisitions. A dose metric that quantifies the peak absorbed skin dose (PSD) is therefore of great importance, both in terms of patient specific follow-up and for imaging protocol optimization. Presently, the cumulative interventional reference point (IRP) air Kerma is the most common skin dose estimation metric in use. This metric lacks several important dose contributions, such as pre-patient attenuation, air-to-skin medium correction, scattering from the patient and the support table, and fluence correction for actual source-to-skin distance. In this manuscript, we present a novel methodology for estimating the maximum absorbed skin dose by using dose related X-ray equipment parameters, such as peak tube voltage, support table position and IRP air Kerma obtained from radiation dose structured reports (RDSR) generated by modern IR equipment. In particular, Siemens Artis Zee (Siemens Healthineers, Erlangen, Germany) and Philips Allura Clarity (Philips, Amsterdam, Netherlands). The calculation process was automated by the development of a series of programming scripts in the PythonTM programming language v3.6 (Python Software Foundation), together with a database storing correction factors and machine specific parameters such as half-value layer (HVL). The proposed calculation model enables the implementation of a dose metric which corresponds better to absorbed skin dose than IRP air Kerma in clinical settings. However, extensive future work is required for a complete PSD implementation, in particular, the development of a skin dose map in which the spatial location of each irradiation event is tracked.