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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Dynamical Systems Methods Applied to the Michaelis-Menten and Lindemann Mechanisms

Calder, Matthew Stephen January 2009 (has links)
In the first part of this thesis, we will explore an iterative procedure to determine the detailed asymptotic behaviour of solutions of a certain class of nonlinear vector differential equations which approach a nonlinear sink as time tends to infinity. This procedure is indifferent to resonance in the eigenvalues. Some attention will be given to finding approximations to solutions which are themselves flows. Moreover, we will address the writing of one component in terms of another in the case of a planar system. In the second part of this thesis, we will explore the Michaelis-Menten mechanism of a single enzyme-substrate reaction. The focus is an analysis of the planar reduction in phase space or, equivalently, solutions of the scalar reduction. In particular, we will prove the existence and uniqueness of a slow manifold between the horizontal and vertical isoclines. Also, we will determine the concavity of all solutions in the first quadrant. Moreover, we will establish the asymptotic behaviour of all solutions near the origin, which generally is not given by a Taylor series. Finally, we will determine the asymptotic behaviour of the slow manifold at infinity. Additionally, we will study the planar reduction. In particular, we will find non-trivial bounds on the length of the pre-steady-state period, determine the asymptotic behaviour of solutions as time tends to infinity, and determine bounds on the solutions valid for all time. In the third part of this thesis, we explore the (nonlinear) Lindemann mechanism of unimolecular decay. The analysis will be similar to that for the Michaelis-Menten mechanism with an emphasis on the differences. In the fourth and final part of this thesis, we will present some open problems.
2

Dynamical Systems Methods Applied to the Michaelis-Menten and Lindemann Mechanisms

Calder, Matthew Stephen January 2009 (has links)
In the first part of this thesis, we will explore an iterative procedure to determine the detailed asymptotic behaviour of solutions of a certain class of nonlinear vector differential equations which approach a nonlinear sink as time tends to infinity. This procedure is indifferent to resonance in the eigenvalues. Some attention will be given to finding approximations to solutions which are themselves flows. Moreover, we will address the writing of one component in terms of another in the case of a planar system. In the second part of this thesis, we will explore the Michaelis-Menten mechanism of a single enzyme-substrate reaction. The focus is an analysis of the planar reduction in phase space or, equivalently, solutions of the scalar reduction. In particular, we will prove the existence and uniqueness of a slow manifold between the horizontal and vertical isoclines. Also, we will determine the concavity of all solutions in the first quadrant. Moreover, we will establish the asymptotic behaviour of all solutions near the origin, which generally is not given by a Taylor series. Finally, we will determine the asymptotic behaviour of the slow manifold at infinity. Additionally, we will study the planar reduction. In particular, we will find non-trivial bounds on the length of the pre-steady-state period, determine the asymptotic behaviour of solutions as time tends to infinity, and determine bounds on the solutions valid for all time. In the third part of this thesis, we explore the (nonlinear) Lindemann mechanism of unimolecular decay. The analysis will be similar to that for the Michaelis-Menten mechanism with an emphasis on the differences. In the fourth and final part of this thesis, we will present some open problems.
3

Variedades inerciais em um modelo atmosférico de Lorenz

Domínguez Rodríguez, Jorge Luis January 2006 (has links)
Estimativas de erro são estabelecidas em termos do número de Rossby para a aproximação de Galerkin não linear nas soluções do modelo atmosférico balanceado de Lorenz com massa forçante. Desse modo a aproximação espectral da aproximação de Galerkin não linear é ligada ao número de Rossby. / Error estimates are established in terms of the Rossby number for a nonlinear Galerkin approximation to the solutions of the balanced atmosphere model of Lorenz with mass forcing. Thereby, the approximation spectral dimension of the nonlinear Galerkin approximation is linked to the Rossby number.
4

Variedades inerciais em um modelo atmosférico de Lorenz

Domínguez Rodríguez, Jorge Luis January 2006 (has links)
Estimativas de erro são estabelecidas em termos do número de Rossby para a aproximação de Galerkin não linear nas soluções do modelo atmosférico balanceado de Lorenz com massa forçante. Desse modo a aproximação espectral da aproximação de Galerkin não linear é ligada ao número de Rossby. / Error estimates are established in terms of the Rossby number for a nonlinear Galerkin approximation to the solutions of the balanced atmosphere model of Lorenz with mass forcing. Thereby, the approximation spectral dimension of the nonlinear Galerkin approximation is linked to the Rossby number.
5

Variedades inerciais em um modelo atmosférico de Lorenz

Domínguez Rodríguez, Jorge Luis January 2006 (has links)
Estimativas de erro são estabelecidas em termos do número de Rossby para a aproximação de Galerkin não linear nas soluções do modelo atmosférico balanceado de Lorenz com massa forçante. Desse modo a aproximação espectral da aproximação de Galerkin não linear é ligada ao número de Rossby. / Error estimates are established in terms of the Rossby number for a nonlinear Galerkin approximation to the solutions of the balanced atmosphere model of Lorenz with mass forcing. Thereby, the approximation spectral dimension of the nonlinear Galerkin approximation is linked to the Rossby number.

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