Thesis (M.S.)--University of North Texas, May, 2008. / Title from title page display. Includes bibliographical references.

Thesis (doctoral)--University of Lund, 1996. / Added t.p. with thesis statement inserted.

Thesis (Ph. D.)--Rutgers University, 2007. / "Graduate Program in Biomedical Engineering." Includes bibliographical references (p. 218-229).

Thesis (Ph. D.)--University of North Texas, August, 2008. / Title from title page display. Includes bibliographical references.

Thesis (doctoral)--University of Lund, 1996. / Added t.p. with thesis statement inserted.

Thesis (Ph.D.)--McMaster University, 2004. / Advisor: Audrey Hicks. Also available via World Wide Web.

Several recent experiments on developing chick spinal cord have established a time window when the developing spinal cord changes from a permissive to a restrictive environment for regeneration. This time window occurs during embryonic days 13-14 (E13-E14) of chick development. Recent experiments in adult rat, have found two proteins that actively inhibit axonal regeneration. This study has sought possible inhibitory proteins, in chicks, correlating to this temporal change. Proteins continuously present after this change (E14-E20) but not before (E11) were identified. Two-dimensional gel electrophoresis was used for separatation of the proteins. Seven protein spots of interest demonstrated this correlative late-expressing neural protein (LNP) profile. Although the functions of these proteins could not be ascertained in this study, further investigation is warranted. / Science, Faculty of / Zoology, Department of / Graduate

The studies reported in this dissertation constitute the first evidence that methylprednisolone (MP) has been shown to ameliorate specific components of secondary trauma including ischemia, lactic acidosis, and lipid peroxidation.

No description available.

There is an increasing demand for spinal surgery and a growing number of new spinal implants and surgical procedures being offered by orthopaedic companies. However, the testing of spinal implants and spinal instrumentation is problematic, with testing in cadavers and animals becoming increasingly difficult and both having significant limitations. Thus the aim of this research is to develop an artificial laboratory spine that will have the same physical and biomechanical properties as the human spine. Validation of computer model is difficult hence an active artificial laboratory spine is being developed. A number of spinal elements have been produced and are being investigated, including an artificial intervertebral disc with different material properties to allow it to simulate different clinical conditions. The study is the first of its kind with the characteristics of the disc material that have been assessed in the laboratory, artificial muscles and spring elements and with normal physiological movements compared and validated from the reported literature. The model was used to investigate the potential of Shape Memory Alloy wires to act as artificial muscles and to control the movement of the spine. It is anticipated that the laboratory spine will have a number of other applications, in particular in the assessment of spinal instrumentation and testing. An actual geometry laboratory spine is also generated with suitable manufacturing technique for intervertebral disc, which has an accurate surface profile to fit between the two vertebral bodies above and below it, is discussed in this thesis.