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The role of Syk protein tyrosine kinase in B cell development and functionSchweighoffer, Edina January 2002 (has links)
No description available.
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TP53 polymorphisms and haplotypes in breast, cervical and ovarian cancerGornall, Robert J. January 2000 (has links)
No description available.
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p53 epitopes as potential tumour targets for immunotherapy programmes against cancersMcArdle, Stephanie January 2000 (has links)
The tumour suppressor gene p53 is pivotal in the regulation of program cell death (apoptosis), and point mutations within the gene represent the most common genetic alterations in human cancers. This process can result in the overexpression and/or accumulation of mutated and/or wild-type p53 protein within the cell. Cytotoxic T lymphocytes (CTL) play a critical role in the immune defense by recognising peptide/MHC complexes on the surface of virally infected or tumour cells followed by lysis. Therefore, p53-derived peptides are potential candidates for immunisation strategies designed to induce anti-tumour CTL in patients.
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Analysis of expressed sequence tags mapping to the critical region of the 5q syndromeStrickson, Amanda J. January 2002 (has links)
No description available.
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An investigation of antiproliferative genes on human chromosome 9England, Nicole Lesley January 1996 (has links)
No description available.
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Analysis of human p53 function in fission yeast : a no-hybrids approachWaddell, Scott January 1996 (has links)
No description available.
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Expression of oestrogen receptor-#alpha# in human cancer cell linesO'Doherty, Aideen Maire January 1999 (has links)
No description available.
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An investigation into loss of cell-cycle control in oesophageal carcinomaMorgan, R. J. January 1998 (has links)
No description available.
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Alterations to the tumour suppressor genes p53 and dcc in colorectal neplasiaFroggatt, Nicola Jane January 1993 (has links)
No description available.
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An investigation of genetic alterations in gastric and colorectal cancerSud, Richa January 1998 (has links)
No description available.
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