Submitted by Jhosep Victorino Beltrán Ramirez (jhosep@ift.unesp.br) on 2018-04-30T23:53:58Z No. of bitstreams: 1 Thesis final version.pdf: 1232865 bytes, checksum: 9c45a7f2b11fb5626fc2289be640684d (MD5) / Rejected by Hellen Sayuri Sato null (hellen@ift.unesp.br), reason: Solicitamos que realize correções na submissão seguindo as orientações abaixo - Incluir Resumo no PDF Agradecemos a compreensão on 2018-05-02T17:34:18Z (GMT) / Submitted by Jhosep Victorino Beltrán Ramirez (jhosep@ift.unesp.br) on 2018-05-03T02:49:03Z No. of bitstreams: 1 TesisDKP.pdf: 952544 bytes, checksum: 7ba12d74da05e9e6a1834ff32937078d (MD5) / Rejected by Hellen Sayuri Sato null (hellen@ift.unesp.br), reason: Solicitamos que realize correções na submissão seguindo as orientações abaixo: - incluir palavras-chave no PDF após o resumo - incluir Key words no PDF após o abstract Agradecemos a compreensão on 2018-05-03T17:25:11Z (GMT) / Submitted by Jhosep Victorino Beltrán Ramirez (jhosep@ift.unesp.br) on 2018-05-04T01:04:35Z No. of bitstreams: 1 TesisDKP.pdf: 952865 bytes, checksum: 283f93ab15503686eccf06947a681380 (MD5) / Approved for entry into archive by Hellen Sayuri Sato null (hellen@ift.unesp.br) on 2018-05-04T18:33:41Z (GMT) No. of bitstreams: 1 beltranramirez_jv_dr_ift.pdf: 952865 bytes, checksum: 283f93ab15503686eccf06947a681380 (MD5) / Made available in DSpace on 2018-05-04T18:33:41Z (GMT). No. of bitstreams: 1 beltranramirez_jv_dr_ift.pdf: 952865 bytes, checksum: 283f93ab15503686eccf06947a681380 (MD5) Previous issue date: 2018-03-02 / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Nesta tese utilizamos a teoria de perturbação causal para estudar a eletrodinâmica quântica escalar com os campos de Duffin-Kemmer-Petiau. Determinamos as seções de choque diferenciais no nível da árvore, o tensor de polarização do vácuo, a função de auto energia e a renormalizabilidade da teoria. Depois disso, comparamos nossos resultados com os obtidos através dos campos de Klein-Gordon-Fock, determinando que eles não são completamente equivalentes / In this Thesis we use causal perturbation theory to study scalar quantum electrodynamics with Du n-Kemmer-Petiau elds. We determine the differential cross sections at the tree level, the vacuum polarization tensor, self energy function and the normalizability of the theory. After that, we compare our results with those ones obtained via Klein-Gordon-Fock elds determining that they are not completely equivalenttf

This thesis is focused on the evaluation of traditional chinese medicine (TCM) assortment of plants in the experimental garden ZF MENDELU. 51 species were evaluated by their aesthetic qualities. 43 species were used for harvesting and processing of drugs. These were described botanically and new information of the content of substances, the use and dosage of drugs were collected. The practical part of theses was scoped to the measurement of chemical substances content in plants. Total amount of flavonoids (TFC), phenols (TPC) and total antioxidant capacity (TAC) by FRAP and DPPH method has been investigated. For 13 plants was determined yield of essential oil. For species used in fresh state, concentration of vitamin C has also been determined. Some annual and perrenial species has been added to the assortment of cultivated plants. The list of plant species TCM, which are perspective for cultivation in the Czech Republic, has been also created.

L’imagerie 3γ est une nouvelle technique d’imagerie médicale nucléaire qui a été proposée au laboratoire Subatech. Cette technique consiste à localiser tridimensionellement la position de la désintégration d’un radioisotope innovant émetteur (β+, γ), le 44Sc. Il s’agit pour cela d’associer la détection des deux photons gamma de 511 keV issus de la désintégration d’un positon, assurée par une couronne de détecteurs de tomogaphie à émission de positon, à la détection dutroisième photon par un télescope Compton au xénon liquide. La position de l’interaction entre le photon et le xénon, ainsi que l’énergie déposée, sont relevées grâce à la mesure du signal d’ionisation à l’aide d’un chambre MICROMEGAS (MICROMEsh GAseousStructure), tandis que le déclenchement de l’acquisition et la mesure du temps de l’interaction sont assurés parla détection du signal de scintillation. Le principe de la TPC est ainsi utilisé pour l’imagerie Compton.Afin de faire la preuve expérimentale de faisabilité de l’imagerie 3γ, un prototype de petite dimension, XEMIS (XEnon Medical Imaging System), a été développé.Cette thèse constitue une étape importante vers cette preuve de faisabilité. Les travaux qui y sont exposés portent sur la caractérisation de la réponse du détecteur pour un faisceau de gammas de 511 keV et sur l’analyse des données qui en sont issues. La mesure des résolutions en énergie et temporelle seront exposés, ainsi que celle de la pureté du xénon liquide. / 3γ imaging is a new nuclear medical imaging technique which has been suggested by Subatech laboratory. This technique involves locating three-dimensional position of the decay of an innovative radioisotope (β+, γ) emitter the 44Sc. The principle consist in the detection of two photons of 511 keV gamma rays from the decay of the positron, provided by a PET ring detector, associated to the detection of the third photon by a Liquid xenon Compton telescope. The energy deposited in the interaction between the photon and xenon and its position are identified by measuring the ionization signal with a MICROMEGAS chamber (MicroMesh Gaseous Structure), while the trigger and time measurement of the interaction are provided by the detection of thescintillation signal. The principle of the TPC is thus usedto Compton imaging.In order to demonstrate experimentally the feasibility of imaging 3γ, a small prototype, XEMIS (Xenon MedicalImaging System) was developed. This thesis is an important step towards the proof of feasibility. In this work are exposed the characterization of the detector response for a beam of 511 keV gamma rays and the analysis of data derived from it. The measurement of energy and time resolutions will be presented, as well as the purity of the liquid xenon.

Galactical and cosmological evidence show that a quarter of the energy budget of our universe is made of collisionless, non-relativistic, and non-baryonic dark matter. Its potential coupling to standard model particles, however, has not yet been understood. One of the leading candidates - Weakly Interacting Massive Particles (WIMP) - allows the production of a dark matter relic density as observed today and couples to standard model particles at or below the weak scale. LUX-ZEPLIN (LZ) is a future tonne-scale two-phase xenon TPC aiming to detect WIMP recoils with xenon nuclei. The experiment will begin WIMP search data-taking in 2020 at the Sanford Underground Research Facility (SURF) in Lead, South Dakota and has a projected sensitivity of 3 × 10^-48 cm² or better in probing a 40 GeV/c² WIMP. The main observables of particle interactions in LZ are the primary scintillation (S1) and secondary scintillation (S2). However, optimising and achieving a stable S2 signal in such a tonne-scale TPC is non-trivial. Effects from the structural design of the S2 production region (top-corner structure), TPC tilt, and the xenon circulation system requires precise monitoring of the liquid surface. Such monitoring is achieved by the capacitive liquid level sensors developed within this thesis. The sensors are strategically placed to ensure that nonuniformity of the S2 signal due to the effects can be understood and corrected. In this thesis, the development of a monitoring system designed to optimise the quality of the S2 signal, based on the capacitive level sensors is discussed. A design of the electronics scheme based on a differential measurement allows femtofarad precision measurement of sensor's capacitance at picofarad level, even in the presence of cable capacitance at nanofarad level. A systematic study of the response of such a sensor to LXe and the application of the precision level sensors to two-phase TPC was carried out. Findings of intrinsic influences from LXe artefacts and LXe dielectric constant variation with its saturated temperature are identified; the result on the application of the sensors contributes to the designs of LZ circulation and the top-corner region. The final LZ level sensors show an artefact-free liquid level measurement and a 12 μm precision in measuring liquid nitrogen level (projection for LXe: ∼ 9 μm) over a 20 mm measurement range.

Este trabajo ha sido realizado en la Organización Europea para la Investigación Nuclear (CERN) y forma parte del proyecto de investigación Europeo para futuros aceleradores lineales (EUDET). En física de partículas existen diferentes categorías de detectores de partículas. El diseño presentado esta centrado en un tipo particular de detector de trayectoria de partículas denominado TPC (Time Projection Chamber) que proporciona una imagen en tres dimensiones de las partículas eléctricamente cargadas que atraviesan su volumen gaseoso. La tesis incluye un estudio de los objetivos para futuros detectores, resumiendo los parámetros que un sistema de adquisición de datos debe cumplir en esos casos. Además, estos requisitos son comparados con los actuales sistemas de lectura utilizados en diferentes detectores TPC. Se concluye que ninguno de los sistemas cumple las restrictivas condiciones. Algunos de los principales objetivos para futuros detectores TPC son un altísimo nivel de integración, incremento del número de canales, electrónica más rápida y muy baja potencia. El principal inconveniente del estado del arte de los sistemas anteriores es la utilización de varios circuitos integrados en la cadena de adquisición. Este hecho hace imposible alcanzar el altísimo nivel de integración requerido para futuros detectores. Además, un aumento del número de canales y frecuencia de muestreo haría incrementar hasta valores no permitidos la potencia utilizada. Y en consecuencia, incrementar la refrigeración necesaria (en caso de ser posible). Una de las novedades presentadas es la integración de toda la cadena de adquisición (filtros analógicos de entrada, conversor analógico-digital (ADC) y procesado de señal digital) en un único circuito integrado en tecnología de 130nm. Este chip es el primero que realiza esta altísima integración para detectores TPC. Por otro lado, se presenta un análisis detallado de los filtros de procesado de señal. Los objetivos más importantes es la reducció / García García, EJ. (2012). Novel Front-end Electronics for Time Projection Chamber Detectors [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/16980 / Palancia

La radioactivité deux-protons est un mode de décroissance du noyau atomique ne se produisant que pour des noyaux extrêmement riches en protons, situés au-delà de la limite de cohésion proton des noyaux (drip line). Prédit dans les années 1960, ce phénomène n’a été mis en évidence expérimentalement qu’en 2002 avec l’observation de la décroissance de 45Fe. Jusqu’à maintenant, seuls quatre noyaux se désintégrant par radioactivité deux-protons étaient connus : 45Fe, 48Ni, 54Zn et 19Mg. La recherche de nouveaux émetteurs a été menée lors d’une expérience avec le dispositif EURICA-WAS3ABi au centre RIKEN Nishina en 2015. La décroissance de 59Ge, 63Se, 67Kr et 68Kr a été observée pour la première fois. La radioactivité deux-protons de 67Kr a pu être étudiée ainsi que la décroissance bêta et l’émission retardée de protons de noyaux exotiques de la région. Une chambre à projection temporelle ou TPC (Time Projection Chamber) conçue par le CENBG (2004-2011) a permis d’étudier les corrélations entre les protons pour 45Fe et 54Zn. Une deuxième génération de TPC est développée au sein de la collaboration ACTAR TPC (ACtive TARget for TPC). Ce détecteur doit permettre une vraie reconstruction tridimensionnelle de l’énergie déposée par les particules dans le volume actif, afin d’obtenir une reconstruction des traces plus performantes que l’ancienne TPC. L’électronique générique GET (General Electronics for TPCs) gère le traitement et l’acquisition des signaux. La caractérisation de l’électronique GET ainsi que du démonstrateur de la TPC au CENBG est le deuxième aspect de ce travail de thèse. / Two-proton radioactivity is a decay mode of proton-rich nuclei located beyond the proton nuclear existence limit (drip line). Predicted in the 1960s, this process was observed for the first time in 2002 in the 45Fe decay study. Only four two-proton emitters were known so far: 45Fe, 48Ni, 54Zn and 19Mg. A search for new emitters was performed with the EURICA- WAS3ABi setup at the RIKEN Nishina center in 2015. The decay of 59Ge, 63Se, 67Kr and 68Kr was observed for the first time. Two-proton radioactivity of 67Kr together with the beta and delayed proton decay of exotic nuclei in the region were studied. A time projection chamber (TPC) developed at the CENBG (2004-2011) enabled the study of the correlations between the protons for 45Fe and 54Zn. A second generation of TPC is under construction within the ACTAR TPC (ACtive TARget for TPC) collaboration. This detector enables a reconstruction in three dimensions of the energy deposited in the active volume which allows a more efficient reconstruction of the tracks as compared to the previous TPC. The generic electronics GET (General Electronics for TPCs) manages the processing and acquisition of the signals. The characterisation of the GET electronics and the TPC demonstrator at CENBG is devoted to the second aspect of this PhD work.

L’Univers est principalement constitué d’un ensemble d’éléments non baryoniques et non lumineux appelé la matière noire. L’un des candidats actuellement favorisés est une particule massive interagissant faiblement avec la matière ordinaire (WIMP) issue du Big Bang. Le programme DarkSide vise à la détection directe de WIMPs à l’aide d’une chambre à projection temporelle utilisant de l’argon liquide en double phase. La première étape de l’expérience, DarkSide-50 ( (46 ± 0,7) kg de masse active) est en cours d’exécution. Une première campagne, avec un remplissage d’argon atmosphérique(AAr), a produit la meilleure limite sur la section efficace WIMP-nucleon jamais obtenue par une expérience à base d’argon. La deuxième phase, avec un remplissage d’argon souterrain (UAr, appauvri en Ar-39), représente une étape importante vers la construction de DarkSide-20k, une expérience à bas bruit de fond avec une masse fiducielle de 20 t. Ce travail est principalement consacré à la description de la simulation Monte Carlo de DarkSide (G4DS), et à ses applications. G4DS, basé sur GEANT4, fournit la description géométrique de chaque détecteur du programme DarkSide ; il a été calibré afin de reproduire la réponse de DarkSide-50 avec une précision de l’ordre de 1 % et intègre un modèle spécifiquement développé pour la description des mécanismes d’ionisation et de scintillation dans l’argon liquide, étalonné sur des données expérimentales. Les principales applications de la simulation comprennent l’estimation du bruit de fond dû aux neutrons et gammas pour DarkSide-50, la mesure du facteur d’appauvrissement de l’Ar-39 en UAr par rapport à l’AAr et les études de conception pour DarkSide-20k. / A wide range of observational evidence suggests that the matter content of the Universe is dominated by a non-baryonic and non-luminous component: dark matter. One of the most favored candidate for dark matter is a big-bang relic population of Weakly Interacting Massive Particles (WIMPs). The DarkSide program aims to the direct detection of WIMPs with a dual-phase liquid argon TPC and a background free exposure. The first phase of the experiment, DarkSide-50, is running since Oct 2013 and has (46 ± 0.7) kg active mass. A first run, with an atmospheric argon fill (AAr), provided the most sensitive limit ever obtained by an argon-based experiment. The current run, with an underground argon fill (UAr, depleted in Ar-39), represents a milestone towards the construction of DarkSide-20k, a low-background dual-phase TPC with a fiducial mass of 20 t. This work is been mainly devoted to the description of G4DS, the DarkSide Monte Carlo simulation, and to its applications. G4DS is a GEANT4-based simulation, it provides the geometry description of each detector of the DarkSide program, it is tuned to reproduce the DarkSide-50 response at the percent level and incorporates a custom model for ionization and scintillation mechanisms in liquid argon, tuned on real data. The principal applications of the simulation include the estimate of the neutron and gamma backgrounds for DarkSide-50, the measurement of the Ar-39 depletion factor in UAr with respect to AAr and the design studies for DarkSide-20k.

L'imagerie 3γ est une nouvelle technique d'imagerie médicale nucléaire qui a été proposée au laboratoire Subatech. Cette technique consiste à localiser tridimensionellement la position de la désintégration d'un radioisotope innovant émetteur (β+, γ), le 44Sc. Il s'agit pour cela d'associer la détection des deux photons gamma de 511 keV issus de la désintégration d'un positon, assurée par une couronne de détecteurs de tomogaphie à émission de positon, à la détection dutroisième photon par un télescope Compton au xénon liquide. La position de l'interaction entre le photon et le xénon, ainsi que l'énergie déposée, sont relevées grâce à la mesure du signal d'ionisation à l'aide d'un chambre MICROMEGAS (MICROMEsh GAseousStructure), tandis que le déclenchement de l'acquisition et la mesure du temps de l'interaction sont assurés parla détection du signal de scintillation. Le principe de la TPC est ainsi utilisé pour l'imagerie Compton.Afin de faire la preuve expérimentale de faisabilité de l'imagerie 3γ, un prototype de petite dimension, XEMIS (XEnon Medical Imaging System), a été développé.Cette thèse constitue une étape importante vers cette preuve de faisabilité. Les travaux qui y sont exposés portent sur la caractérisation de la réponse du détecteur pour un faisceau de gammas de 511 keV et sur l'analyse des données qui en sont issues. La mesure des résolutions en énergie et temporelle seront exposés, ainsi que celle de la pureté du xénon liquide.

A typical E-commerce system that is deployed on the Internet has multiple layers that include Web users, Web servers, application servers, and a database server. As the system use and user request frequency increase, Web/application servers can be scaled up by replication. A load balancing proxy can be used to route user requests to individual machines that perform the same functionality. <br><br>To address the increasing workload while avoiding replicating the database server, various dynamic caching policies have been proposed to reduce the database workload in E-commerce systems. However, the nature of the changes seen by the database server as a result of dynamic caching remains unknown. A good understanding of this change is fundamental for tuning a database server to get better performance. <br><br> In this study, the TPC-W (a transactional Web E-commerce benchmark) workloads on a database server are characterized under two different dynamic caching mechanisms, which are generalized and implemented as query-result cache and table cache. The characterization focuses on response time, CPU computation, buffer pool references, disk I/O references, and workload classification. <br><br>This thesis combines a variety of analysis techniques: simulation, real time measurement and data mining. The experimental results in this thesis reveal some interesting effects that the dynamic caching has on the database server workload characteristics. The main observations include: (a) dynamic cache can considerably reduce the CPU usage of the database server and the number of database page references when it is heavily loaded; (b) dynamic cache can also reduce the database reference locality, but to a smaller degree than that reported in file servers. The data classification results in this thesis show that with dynamic cache, the database server sees TPC-W profiles more like on-line transaction processing workloads.

A typical E-commerce system that is deployed on the Internet has multiple layers that include Web users, Web servers, application servers, and a database server. As the system use and user request frequency increase, Web/application servers can be scaled up by replication. A load balancing proxy can be used to route user requests to individual machines that perform the same functionality. <br><br>To address the increasing workload while avoiding replicating the database server, various dynamic caching policies have been proposed to reduce the database workload in E-commerce systems. However, the nature of the changes seen by the database server as a result of dynamic caching remains unknown. A good understanding of this change is fundamental for tuning a database server to get better performance. <br><br> In this study, the TPC-W (a transactional Web E-commerce benchmark) workloads on a database server are characterized under two different dynamic caching mechanisms, which are generalized and implemented as query-result cache and table cache. The characterization focuses on response time, CPU computation, buffer pool references, disk I/O references, and workload classification. <br><br>This thesis combines a variety of analysis techniques: simulation, real time measurement and data mining. The experimental results in this thesis reveal some interesting effects that the dynamic caching has on the database server workload characteristics. The main observations include: (a) dynamic cache can considerably reduce the CPU usage of the database server and the number of database page references when it is heavily loaded; (b) dynamic cache can also reduce the database reference locality, but to a smaller degree than that reported in file servers. The data classification results in this thesis show that with dynamic cache, the database server sees TPC-W profiles more like on-line transaction processing workloads.