In this paper, I will try to answer the question how the aesthetic idea in Kant’s aesthetic theory accounts for the universal validity of the subjective judgment of taste, and what the nature of the aesthetic idea is that makes such account possible. This claim about universal validity of the subjective judgment of taste in Kant’s philosophy is regarded to be problematic because of the seeming contradiction between the subjectivity of a judgment and its universality. What can solve this contradiction, from my point of view, is the role of the aesthetic idea that it plays in the judgment of taste and the subjective principle that puts cognitive powers of mind in a harmonious free relationship. The main feature that makes the aesthetic idea the source of the universal validity is its universal communicability expressed in the universally pleasurable feeling of the judgment of taste.

Olfactory sensing is ubiquitous across animals and important for survival. Yet, its characteristics, mechanisms, and functions in humans remain not well understood. In this dissertation, I present four studies on human olfactory perception. Study I investigates the impact of short-term exposures to an odorant on long-term olfactory learning and habituation, while Study II examines human ability to localize smells; Study III probes visual-olfactory integration of object representations, and Study IV explores the role of olfaction in sensing nutrients. Several conclusions are drawn from these studies. First, brief intermittent exposures to even a barely detectable odorant lead to long-term incremental odorant-specific habituation. Second, humans localize smells based on gradient cues between the nostrils. Third, there is a within-hemispheric advantage in the integration of visual-olfactory object representations. Fourth, olfaction partakes in nutrient-sensing and facilitates the detection of food. Some broader implications of our findings are discussed.

Aim: The aim of present study was to determine the frequency of taste and smell disorders occuring in patients receiving chemotherapy for cancer. Methods: The study was of an empirical cross sectional quantitative descriptive design. During one month, consecutive cancer patients at outpatient units in two Swedish hospitals were asked to participate in the study by completing a questionnaire that had been developed previously for a similar study. All participants had undergone at least 1 cycle of intravenous chemotherapy or  a minimum of seven days of oral chemotherapy. Results: A total of 102 patients completed the questionnaire. Results show that 55 % experienced taste disorders and  42 % experienced smell disorders. Both disorders are more common in women than in men. Of patients with taste disorders 47 % reported that it  impacted on their daily life to some degree and of patients with smell disorders the corresponding number was 33%. Patients with smell disorders reported a smaller degree of impact on their daily life than did patients with taste disorders. Conclusion: Both taste and smell disorders are common in cancer patients treated within chemotherapy. More research into factors that might eliminate or dimnish these problems is needed.

Discrimination between edible and contaminated foods is crucial for the survival of animals. In Drosophila, a family of gustatory receptors (GRs) expressed in taste neurons is thought to mediate the recognition of sugars and bitter compounds, thereby controlling feeding behavior. Using the Gal4/UAS system, we have characterized the expression of Gr genes in detail, and find that gene expression falls into two distinct groups. The first group, which make up the majority of the genes analyzed, are co-expressed with Gr66a, and functional ablation of taste neurons expressing these genes demonstrates that these neurons mediate sensitivity to bitter substrates. A second, distinct group of taste neurons, express Gr5a and mediate sensitivity to trehalose. We find that these two sub-populations of taste neurons - attractive-type and avoidance-type - project afferents to discrete areas of the primary taste center in the CNS. These results demonstrate how bitter and sweet taste are coded for in the periphery and indicates that information about different taste modalities is initially segregated in the CNS. We have also used the Gal4/UAS system to thoroughly characterize the expression profile of a cluster of six Grs - Gr28a and Gr28b.a-b.e. We find that these receptors are expressed not only in taste neurons, but other sensory neurons, as well as neurons in the CNS. RNA in situ hybridization confirms this unusual expression pattern. In order to explore the function of these Grs, these genes have been deleted using ends-out homologous recombination, to produce Gr28 mutant flies. Initial behavioral experiments with Gr28 mutant flies suggest that these receptors may play a role in detecting aversive substrates and/or modulate avoidance responses to these substrates. / Dissertation

Thesis (Ph. D.)--University of Missouri-Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 175-187). Also available on the Internet.

Thesis (Ph. D.)--University of Missouri-Columbia, 2000. / Typescript. Vita. Includes bibliographical references (leaves 175-187). Also available on the Internet.

Thesis (Ph.D)--Biology, Georgia Institute of Technology, 2009. / Committee Chair: McCarty, Nael A.; Committee Co-Chair: Kubanek, Julia; Committee Member: Derby, Charles; Committee Member: Goodisman, Michael; Committee Member: Pardue, Machelle; Committee Member: Weissburg, Marc. Part of the SMARTech Electronic Thesis and Dissertation Collection.

Thesis (Ph. D.)--University of Washington, 2002. / Vita. Includes bibliographical references (leaves 112-132).

The behavior and facial expressions performed by cats have been reported to be visibly affected by the perceived taste quality of a food item. The goal of the present study was to assess how cats react to pleasant and unpleasant tastes. The facial and behavioral reactions of 13 cats to different concentrations of L-Proline and quinine monohydrochloride as well as mixtures with different concentrations of the two substances were assessed using a two-bottle preference test. The cats were videotaped during the tests and the frequency and duration of 50 different behaviors was analyzed in Noldus the Observer XT. The cats responded to tastes regarded as pleasant by having their eyes less than 50 % open for significantly longer periods of time compared to a water control. Tongue protrusions were also observed significantly more frequently when the cats sampled from a solution with a preferred taste compared to a water control. When encountering solutions of quinine monohydrochloride or mixtures containing quinine monohydrochloride the cats were observed to perform tongue protrusion gapes much more frequently compared to a water or L-Proline control. Even though the cats did not significantly differ in the number of times they licked at spouts containing the 50 mM L-Proline and 500 mM quinine monohydrochloride mixture compared to a 50 mM L-Proline, no masking effect could be confirmed as there was no increase in the acceptance of the mixture was observed. The present study suggests that the knowledge about behavioral responses to pleasant or unpleasant taste can be utilized in future studies on how cats perceive different tastes.

Background: The relationship between fruit and vegetable (FV) exposure, preference, and consumption among children has been a targeted topic of study due to the increasing prevalence of childhood obesity. The purpose of this study was to examine FV home exposure in elementary children and the selection of both fruits and vegetables and less familiar lunch entrées at school. Design: Cross-sectional data on 3rd, 4th, and 5th grade students (N=59) from an elementary school in central Texas. Methods: Home and school FV exposure was collected via self-report using a six-item questionnaire. Students were placed into high and low groups for 1) the variety of FV offered at home, and 2) the variety of FV eaten at home. Absolute and relative ratings of eight lunch entrées were collected through taste-tests conducted at school. Results: Differences in the consumption of FV at school and the selection of lunch entrées between high and low groups were analyzed using Mann-Whitney U independent non-parametric tests. Results indicated that the distribution of consumption at school differed across high and low groups for parental offering of FV for: oranges (z=2.16, p<0.05), cucumber (z=2.44, p<0.05), pineapple (z=3.41, p=0.001), mandarin oranges (z=2.93, p<0.01), tomato (z=3.14, p<0.01), and broccoli (z=3.26, p=0.001). The distribution of consumption at school across high and low groups for the eating FV at home was significant for 10 out of the 11 FV items: oranges (z=2.24, p<0.05), cucumber (z=2.64, p<0.01), pineapple (z=4.19, p<.001), mandarin oranges (z=3.06, p<0.01), tomatoes (z=3.47, p=0.001), bell pepper (z=2.25, p<0.05), broccoli (z=4.00, p<0.001), melon (z=3.06, p<0.01), apples (z=2.79, p<0.01), and zucchini (z=2.27, p<0.05) Likewise, significant differences between high and low groups for parental offering of FV were found for the selection of the chef salad (z=2.546, p<0.05), the Greek salad (z=2.091, p<0.05), and the veggie humus plate (z=2.104, p<0.05). Absolute and relative ratings of eight lunch entrées are also reported. Conclusions: Children who are more frequently exposed to FV at home consume a wider variety FV at school and are more likely to select healthy, less familiar entrées at school lunch. / text