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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 1 to 4 of 4 (0.018 seconds)Spelling suggestions: "subject:"temozolomid"" "subject:"temozolomide""
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Extendierte adjuvante Chemotherapie mit Temozolomid in der Behandlung maligner Gliome - Eine retrospektive Datenanalyse zur Wirksamkeit und Hämatotoxizität im klinischen Alltag / Extended adjuvant chemotherapy with temozolomide in the treatment of malignant glioma - A retrospective data analysis of efficacy and hematotoxicity in clinical practiceKarges, Julia 29 October 2018 (has links)
No description available.
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Optimalizace dávky temozolomidu pro redukci neurogeneze u laboratorního potkana / Otimization of a dose of temozolomide for efficient reduction of adult neurogenesis in the laboratory ratPištíková, Adéla January 2014 (has links)
The goal of this study is to find an optimal dose of cytostatic Temozolomide (TMZ) for Long-Evans strain of rats. This dose should reduce neurogeneis while having a minimal pernicious health side-effects. Temozolomide is newly used to suppress neurogenesis but similarly to any other cytostatic has an effect on all dividing cells in an organism. This can affect health of an animal. Contrary to the mice, there was no systematic attempt to establish optimal dose. In our experiment rats were divided into four groups - one control group and three treatment groups which received different doses of temozolomide (10, 25, 40 mg/kg of TMZ). To detect level of neurogenesis cells were labeled by bromodeoxyuridine. During the experiment blood element counts were assessed, sensorimotoric tests were conducted, and weight increment was monitored. The results indicate that dose of 10mg/kg is adequate as it reduces neurogenesis by 64% compared to the control group and does not significantly differ from higher doses. In this group weight increment is comparable with the control group, while in the higher doses of TMZ weight increment is significantly lower. Effect of myelosupression is same for all treatment groups.
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Einfluss der Adjutanten Chemotherapie mit Temozolomid auf die Zeit bis zum Tumorrezidiv bei Patienten mit Glioblastom / Adjuvant chemotherapy with Temozolomide for patients with glioblastoma and its impact on progression free survivalGrabert, Josefin 20 May 2014 (has links)
No description available.
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Untersuchungen zur Wirksamkeit von Dacarbazin und Temozolomid bei der Behandlung des kutanen Melanoms in Assoziation mit DNA-Reparatur / Assessment of the Efficacy of Dacarbazine and Temozolomide in Melanoma Treatment in Association with DNA-RepairBöckmann, Lars 15 January 2010 (has links)
No description available.
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