Submitted by Sara Ribeiro (sara.ribeiro@ucb.br) on 2017-04-05T20:33:17Z No. of bitstreams: 1 JoseFernandodeOliveiraTese2017.pdf: 2874980 bytes, checksum: 2f96c863658b7f42f17e67ca0b4ea1a1 (MD5) / Made available in DSpace on 2017-04-05T20:33:17Z (GMT). No. of bitstreams: 1 JoseFernandodeOliveiraTese2017.pdf: 2874980 bytes, checksum: 2f96c863658b7f42f17e67ca0b4ea1a1 (MD5) Previous issue date: 2016-12-14 / Systemic arterial hypertension is a global health problem, affecting even the adolescent population, in this age group, genetic predisposition and biopsychosocial modifications are important factors in the development of hypertension. However, few studies have analyzed and associated the combination of family history, physical activity level, anthropometric profile and physical fitness on blood pressure reactivity and nitric oxide bioavailability in adolescents submitted to the Shuttle Run 20 meters, Cold Pressor Test and palmar grip strength. A total of 172 adolescents (n = 60???, n = 112???), high school students of the Technical College of Campinas-SP, aged 14 to 18 years, were classified into: normotensive children (FN; = 38???, n = 48???) and hypertensive children (FH; n = 22???; n = 64???), subdivided into active and sedentary. All procedures followed the ethical requirements of resolution 466/12 of the National Health Council. The results showed significant differences between FN vs. FH in several parameters of physical fitness, hemodynamic components and in salivary nitrite. Therefore, this study demonstrated that FH adolescents already present a negative influence of anthropometric, cardiovascular and physical activity levels on the bioavailability of salivary nitric oxide in children of hypertensive patients. / A hipertens??o arterial sist??mica ?? um problema mundial de sa??de, afetando inclusive a popula????o adolescente, nessa faixa et??ria, a predisposi????o gen??tica e as modifica????es biopsicossociais s??o importantes fatores no que tangem ao desenvolvimento da HAS. Entretanto poucos estudos analisaram e associaram a combina????o do hist??rico familiar, n??vel de atividade f??sica, perfil antropom??trico e a aptid??o f??sica na reatividade press??rica e a biodisponibilidade de ??xido n??trico em adolescentes submetidos ao Shuttle Run 20 metros, Cold Pressor Test e for??a de preens??o palmar. Foram avaliados 172 adolescentes (n=60???; n=112???), alunos do ensino m??dio do Col??gio T??cnico de Campinas-SP, com idades variando entre 14 e 18 anos, os quais foram classificados em: filhos de normotensos (FN; n=38???; n=48???) e filhos de hipertensos (FH; n=22???; n=64???), subdivididos em ativos e sedent??rios. Todos os procedimentos seguiram as exig??ncias ??ticas da resolu????o 466/12 do conselho nacional de sa??de. Os resultados demonstraram diferen??as significativas entre FN vs. FH em diversos par??metros de aptid??o f??sica, componentes hemodin??micos e no nitrito salivar. Portanto, este estudo demonstrou que adolescentes FH j?? apresentam uma influ??ncia negativa de vari??veis antropom??tricas, cardiovasculares e n??vel de atividade f??sica na biodisponibilidade de oxido n??trico salivar em filhos de hipertensos.