L’innovation permet d’améliorer la santé des patients mais elle est aussi importante pour le développement économique du secteur pharmaceutique. En dépit de son importance, la définition de cette notion dans le domaine de la santé est très complexe. Dans notre travail nous apportons des éléments de réponse à la définition de la notion de « médicament innovant » dans une perspective communautaire et nationale. Puis nous avons procédé à une analyse des normes juridiques appliquées à la régulation du marché des médicaments innovants. L’Union européenne, ainsi que la France, mettent en œuvre des initiatives politiques favorisant la recherche dans le domaine de l’innovation pharmaceutique. Les normes juridiques sont utilisées pour organiser un accès précoce aux médicaments prometteurs ; elles peuvent également inciter au développement de médicaments innovants et jouer un rôle important dans leur valorisation. Une étude comparative entre la France et l’Angleterre a mis en évidence une tendance au développement d’outils similaires utilisés dans le champ de la régulation du marché des médicaments innovants. Enfin, dans ce domaine dans lequel l’innovation n’est pas définie par les usagers, le cadre juridique joue un rôle crucial, renforcé à l’heure actuelle par un contexte de contrainte budgétaire. / Innovation improves the health of patients, and it is also important for economic development of the pharmaceutical sector. Despite its importance, the definition of this concept in the field of healthcare is very complicated. In our work we provide answers to the definition of the term "innovative drug" from European community and national perspectives. Then we analyze the use of legal norms in regulating the market of innovative medicines. The European Union and France have policy initiatives encouraging research of innovative drugs. Legal standards are used to organize early access to promising drugs, they also serve to promote the discovery of innovative drugs, as well as play an important role in the development of these drugs. A comparative study between France and England showed the tendency in using the same tool regulating the market of innovative drugs. Finally, in the field where innovation is not defined by the users a legal framework plays a crucial role, and considering current budget constraints, its role is strengthened.

This investigation used a descriptive approach to explore and evaluate early recollection changes of children in Adlerian counseling. The study addressed seven research questions regarding early recollection change for children in Adlerian counseling as compared with children not in Adlerian counseling. The treatment group was engaged in Adlerian counseling for 10 weeks. The investigator conducted pre-counseling and post-counseling interviews to collect six total early recollections from 9 subjects. The comparison group was not engaged in treatment for counseling. The investigator conducted interviews at an interval of 10 weeks to collect six total early recollections from 9 subjects. The Manaster-Perryraan Manifest Content Early Recollection Scoring Manual was used for analysis of early recollection content. Following training sesions, raters scored absence or presence of content variables in early recollections. Tables were employed to reveal findings of early recollection content change as addressed by the seven research questions of this study. A descriptive evaluation of' the data indicated that the treatment group manifested greater change in early recollection content as compared to the comparison group in six of seven research questions. On the basis of these findings, this study concluded that early recollections of children are a valid source of potential in measuring therapeutic progress and are a reliable measure of the thematic apperception of children. The data from this study provide a foundation from which to build the clinical utility of the early recollections of children. In view of these results, this study recommended the routine use of early recollections of children in Adlerian counseling.

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