Abstract One of the features in Taiwan market is price competition. What makes it even worse are the outflow of investment, more demand on environmental protection, increase of labor cost, and the limit of national policy. These factors make business hardly earn profits. And therefore, how to gain reasonably with limited resources and survive in the competition are the difficulties we need to overcome in Taiwan. Printed Circuit Board played a key role in ¡§Taiwan Financial Miracle¡¨ for the past 10 years. However, the manufacturers now have no choice but to search for new niche to meet the change on the whole business environment. The headquarters staying in Taiwan have to face even more harsh conditions, which come from the demand of cost-down, the price competitions among the same industry. Therefore, it becomes essential to adjust Product Mixed in order to fit the insufficient Product Resources. My study puts focus on ¡§Most Constrained Station¡¨ from the Theory of Constraint. It helps PCB manufacturers, who suffers slim profit, find out the best Products Mixed in accordance of Throughput Contribution. Each product brings different profit and cost. Some may share common resources, and some may not, when they are put in the process line. Therefore, to continue forward in the age of slim-profit, the complex of Product Mixed and earnings becomes prominent. Studying Theory of Constraint, I aim to bring forth the best solution on processing contribution by means of figuring out the Throughput Chain in Most Constrained Station and analysis of application on Most Constrained Station. And then I will conclude with the best production strategy for the PCB manufacturer as the main thesis of the research.