Thesis (Ph. D.)--Ohio state University, 1926. / Autobiography. The first two articles are reprinted from Endocrinology, vol. ix, no. 5, and vol. x, no. 1, and the third from the American journal of physiology, v. 78, no. 2. Bibliography at end of each article.

Part of Thesis (Ph. D.)--University of Chicago, 1932. / "Private edition, distributed by the University of Chicago Libraries, Chicago, Illinois." Bibliography: p. 11-12.

Thesis (Ph. D.)--University of Hong Kong, 1994. / Includes bibliographical references.

Part of thesis (Ph. D.)--University of Chicago, 1932. / "Private edition, distributed by the University of Chicago Libraries, Chicago, Illinois." "References": p. 11-12.

Thesis (Ph. D.)--Ohio state University, 1926. / Autobiography. The first two articles are reprinted from Endocrinology, vol. ix, no. 5, and vol. x, no. 1, and the third from the American journal of physiology, v. 78, no. 2. Bibliography at end of each article.

Thyroid nodules represent the most frequent endocrine lession in our population and it is neccessary to differentiate malignant lessions from them. The aim of the study was to validate determination of selected angiogenic, proliferative, and appptotic markers in cytosol tissue extracts. We analysed 166 tissue samples (85 goitres, benign adenomas and 10 malignat tumours in which VEGF, bFGF, Endostatin, Thymidinkinase ans TPS were determined. Main limitation of cytosolic analysis is tissue sample volume, that must be about 1cm3 and interindividual variability caused by tissue sample heterogeneity. Best way is to compare normal with pathological tissue samples from one patient. We fund significant differences amog histological groups in VEGF, bFGF, Endostatin and maily Tymidinkinase and TPS. These differences are not sufficiently huge to distinguish goitres and benign lessions . We also did not find any correlation between cytosolic markers and iminuhistochemistry markers . Cytosol analysis is not able to measure local expression and its differences in anylysed tissue, but it is able to quantitatively determine mean levels of selected markers.

Xenopus Laevis has provided, during the last ten years, the basis of a growing body of physiological enquiries initiated by Jolly's research on reflex action. Its viability in the laboratory and amenability to operative procedure in particular, make it a peculiarly suitable object for investigation. It is regrettable therefore, that existing literature on the anatomy of Xenopus has been directed to elucidating those characteristics which are of especial interest to the Systematists and Morphologists rather than detailed information of a type which is essential to operative procedure. There is in particular no extant account of the endocrine system of Xenopus, although it is evident from superficial inspection that the suprarenal complex differs from that of the more familar Anura. The present enquiry concerns the Thyroid Gland, Pituitary and Epiphyseal Complexes with some observations concerning the possible occurrence of chromophil cells in the kidney of Xenopus laevis. The data have been placed on record specifically and constitution of these organs in physiological operations.

No description available.

No description available.

No description available.