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Osterix is required for skeletal growth and homeostasis after birth : implications in osteoporosis.Zhou, Xin. January 2008 (has links)
Source: Dissertation Abstracts International, Volume: 69-07, Section: B, page: 4115. Advisers: Mary Ann Smith; Benoit de Crombrugghe. Includes bibliographical references.
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Mitochondrial dysfunction in neurodegeneration /Ekstrand, Mats, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 4 uppsatser.
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Cloning and characterization of FREACs, human forkhead transcription factorsGreberg, Maria Hellqvist. January 1997 (has links)
Thesis (doctoral)--Göteborg University, 1997. / Added t.p. with thesis statement inserted.
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Cloning and characterization of FREACs, human forkhead transcription factorsGreberg, Maria Hellqvist. January 1997 (has links)
Thesis (doctoral)--Göteborg University, 1997. / Added t.p. with thesis statement inserted.
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Transcriptional and post-transcriptional regulations of cell junction proteins in mammalian testes施潔玲, Sze, Kit-ling. January 2007 (has links)
published_or_final_version / abstract / Biological Sciences / Doctoral / Doctor of Philosophy
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Studies on the regulation and evolution of tra-1, the terminal somatic sex determining gene in Caenorhabditis elegansDe Bono, Mario Godwin January 1994 (has links)
No description available.
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Regulation of cell type-specific gene expression in melanocytes and melanomaEisen, Timothy George Quentin January 1996 (has links)
No description available.
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New Perspectives on Gata Redundancy in Mouse EmbryogenesisBorok, Matthew Jay January 2015 (has links)
Gata4 and Gata6 are closely related transcription factors that are essential for the development of a number of embryonic tissues. While they have nearly identical DNA-binding domains and similar patterns of expression, Gata4 and Gata6 null embryos have strikingly different embryonic lethal phenotypes. Conditional deletion of these genes in the pancreas has also revealed specific functions for each factor in this organ. To investigate the role of these genes in pancreatic development, we performed a number of biochemical experiments on pancreatic cell lines and mutant tissues. We found that Gata4 and Gata6 regulate overlapping sets of genes in the developing pancreas. To determine whether the lack of global redundancy between Gata4 and Gata6 is due to differences in protein function or Gata4 and Gata6 expression domains, we generated mice that contained the Gata6 cDNA in place of the Gata4 genomic locus. Gata4Gata6/Gata6 embryos survived through embryonic day (e)12.5 and successfully underwent ventral folding morphogenesis, demonstrating that Gata6 is able to replace Gata4 function in extraembryonic tissues. Interestingly, Gata6 is unable to replace Gata4 function in the septum transversum mesenchyme or the epicardium, leading to liver agenesis and lethal heart defects in Gata4Gata6/Gata6 embryos. These studies suggest that Gata4 has evolved distinct functions in the development of these tissues that cannot be performed by Gata6, even when it is provided in the identical expression domain. Our work has important implications for the respective mechanisms of Gata function during development, as well as the functional evolution of these essential transcription factors.
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A mechanism for transcriptional interference between convergent promoters in the developmental switch of bacteriophage 186 / Benjamin Peter Callen.Callen, Benjamin Peter January 2003 (has links)
"March 2003" / Bibliography: leaves 133-143. / x, 143 leaves : ill. (some col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, School of Molecular and Biomedical Sciences, 2003
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Molecular mechanism of Arabidopsis CBF mediated plant cold-regulated gene transcriptional activationWang, Zhibin. January 2006 (has links)
Thesis (Ph. D.)--Ohio State University, 2006. / Full text release at OhioLINK's ETD Center delayed at author's request
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