M.Tech. / Purpose: Posterior mechanical neck pain is considered a debilitating musculoskeletal problem and is one of the most common reasons for visiting an emergency department (Murphy, 2000). Anti-inflammatory creams and gels are readily available to individuals suffering from musculoskeletal pain. The purpose of this study was to determine the effectiveness of Traumeel®S ointment together with chiropractic spinal manipulative therapy as a treatment form for posterior mechanical neck pain, with regards to pain, disability and cervical spine range of motion. Method: This study was a comparative study and consisted of two groups of fifteen. The participants were between the ages of eighteen and forty-five, with a half male to female ratio. The potential participants were examined and accepted according to the inclusion and exclusion criteria. Group A received chiropractic spinal manipulative therapy followed by the application of aqueous cream over the upper trapezius muscle area of the posterior neck. This was the placebo group. Group B received chiropractic spinal manipulative therapy followed by the application of Traumeel®S ointment over the upper trapezius muscle area of the posterior neck. This was the experimental group. Objective and subjective findings were based on the above treatment protocols. Procedure: Treatment consisted of seven consultations over a three week period. Objective and subjective readings were taken at the beginning of the first, fourth and seventh consultations. Subjective readings were taken from the Vernon-Mior Neck Pain and Disability Index as well as from the Visual Analogue Scale (VAS). Objective readings were taken from measurements taken from the Cervical Range of Motion device (CROM). At the first to the sixth consultations participants received spinal manipulative therapy with either the application of aqueous cream or the application of Traumeel®S ointment depending on whether they were in group A or group B. Results: Clinically and statistically significant improvements in both group A and group B were seen over the course of the study with regards to cervical spine range of motion, pain and disability. Conclusion: The results show that both treatment protocols were effective in decreasing cervical spine pain and disability and increasing cervical spine ROM. Group B receiving Traumeel®S ointment did show a greater increase in cervical spine ROM clinically, but statistically there was no significant difference between the two groups.

Pirmą kartą atliktas asmenų grupių, turinčių skirtingą neutrofilų funkcinį aktyvumą (sergančių priedančio audinių uždegimu ir sveikų asmenų), lyginamasis periferinio kraujo neaktyvintų ir aktyvintų neutrofilų oksidacinės funkcijos tyrimas. Tyrimams buvo panaudoti labai jautrūs nuo luminolo ir lucigenino priklausomos chemiliuminescencijos metodai. Pirmą kartą įrodytas homeopatinio preparato Traumeel S antioksidacinis poveikis in vitro, reikšmingai mažinantis sergančiųjų priedančio audinių uždegimu kraujo neutrofilų generuojamo superoksido anijono kiekį. Pirmą kartą tirtas sergančių priedančio audinių uždegimu ir sveikų asmenų periferinio kraujo, plazmos ir serumo redukcinis potencialas, įvertinant homeopatinio preparato Traumeel S poveikį redukciniam potencialui in vitro. Tyrimų rezultatai papildo žinias ir apie priedančio audinių uždegimo patogenezę. / For the first time, a complex comparative study was performed on the oxidative function of non-activated and activated neutrophils of peripheral blood from subject with differing functional activity of neutrophils (i.e. patients with periodontitis and healthy subjects). The study employed two very sensitive techniques – luminol-dependent and lucigenin-dependent chemiluminescence. For the first time, the study showed that the homeopathic medication Traumeel S had antioxidant effect in vitro, i.e. it significantly reduced superoxide anion levels generated by blood neutrophils in patients with periodontitis. The results of the study also complemented knowledge about the pathogenesis of periodontal inflammation. This finding may have a significant clinical implementation.

M.Tech. / Purpose: This study aims to compare the effects of lumbar spine and/or pelvic manipulation, and lumbar spine and/or pelvic manipulation in conjunction with the application of subcutaneous parenteral Traumeel® in the treatment of chronic mechanical low back pain with regards to pain, disability and lumbar spine range of motion. These effects were evaluated using a questionnaire consisting of a Numerical Pain Rating Scale, and an Oswestry Low Back Pain and Disability Questionnaire, and by measuring lumbar spine range of motion using a digital inclinometer. The questionnaire was completed and the range of motion readings were taken prior to treatment on the first, fourth and seventh consultations. Method: Thirty participants who met the inclusion criteria were stratified in number and gender between two groups of equal size (15 participants each). Group one received spinal manipulation to restricted lumbar spine and/or sacroiliac joints followed by the administration of subcutaneous parenteral Traumeel®. The second group received spinal manipulation to restricted lumbar spine and/or sacroiliac joints. Participants were treated six times out of a total of seven sessions, over a maximum three week period. Procedure: Subjective data was collected at the beginning of the first and fourth consultations, as well as on the seventh consultation by means of a Numerical Pain Rating Scale (NPRS) and an Oswestry Low Back Pain Disability Questionnaire in order to assess pain and disability levels. Objective data was collected at the beginning of the first and fourth session, as well as on the seventh consultation by means of a digital inclinometer in order to assess lumbar spine range of motion. Analysis of collected data was performed by a statistician. Results: Clinically significant improvements in group 1 and group 2 were noted over the duration of the study with reference to pain, disability, and lumbar spine range of motion. Statistically significant changes were noted in group 1 and group 2 with reference to pain and disability, and in group 1 with reference to lumbar spine range of motion. vi Conclusion: The results show that both spinal manipulation, as well as spinal manipulation in conjunction with subcutaneous parenteral Traumeel® are effective treatment protocols (as demonstrated clinically, and to a lesser extent, statistically) in decreasing pain and disability, and increasing lumbar spine range of motion in patients with mechanical low back pain. However, neither treatment protocol proved to be preferential. The results carry a possible suggestion that chiropractic manipulation (common to both groups) is effective in ameliorating participant-rated pain and disability, and increasing lumbar spine range of motion in the case of chronic mechanical low back pain.

M.Tech. / Purpose: A study to determine the efficacy of Traumeel® gel using phonophoresis in the treatment of a latent trapezius myofascial trigger point, with regards to pain perception, cervical spine range of motion and pressure pain tolerance.Methods: A single-blinded, controlled study design was utilised. Thirty participants who all presented with a latent trapezius myofascial trigger point were randomly divided into two groups of fifteen. Each individual was subjectively and objectively assessed from baseline values prior to receiving treatment. Group A received ultrasound utilising ultrasound gel over the trapezius myofascial trigger point, as the control group. Group B received phonophoresis with Traumeel® gel over the trapezius myofascial trigger point. All participants received two treatments per week, with a total of seven consultations, over the three week study period. The subjective data was obtained utilising a Numerical Pain Rating Scale (NPRS) whilst a hand held Algometer tested pressure pain tolerance and a Cervical Range of Motion Measuring Instrument (CROM) measured cervical spine range of motion. These were utilised to form the objective data. The Data was analysed using non-parametric tests. The two independent treatment groups were assessed for capability at treatments one, four and seven using the Mann-Whitney U-test (non-parametric version of the independent sample T-test). Changes over the three week period were observed and analyzed using the Repeated Measures test or the Friedman Test (Devey, 2010). Results: In this study ultrasound utilising ultrasound gel had a statistically significant impact on the trapezius myofascial trigger point. Statistical analysis of the Traumeel® gel suggests that there was no statistical significance with regards to any of the treatment parameters or variables measured. Subjectively ultrasound gel proved to be statistically and clinically significant in decreasing the participant’s pain perception. There was no statistical improvement but there was a clinical improvement in the Traumeel® gel group.