1.The prevalence of sow reproductive organ disease was ascertained in the Lithuania’s Republic’s large hog complexes; 2.The dominating microflora in sow reproductive organs and its influence in post-weaning fertilisation were established; 3.The influence of prophylactic use of recommended feed supplements Spectinomix 110 and Lincosint 100 on reproductive organ microflora and piglet to weaning health was evaluated; 4.The prophylactic and treatment efficacy of veterinary preparations 2.5% sol. Cobactan®, Metricure®, Clamoxyl ® Metritis was established in sows with post-partum uterine inflammations.