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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Gabapentinoids for treatment of neuropathic pain: a medicines usage evaluation at the Groote Schuur hospital chronic pain management clinic

Moabelo, Machuene 11 February 2021 (has links)
Background Neuropathic pain (NP), defined as pain caused by a lesion or disease of the somatosensory system, affects 6.9 – 10 % of people worldwide. Pregabalin is currently recommended as a first line drug for NP in South Africa. Methods A cross-sectional retrospective descriptive medicines usage evaluation (MUE) of Pregabalin at Groote Schuur Chronic Pain clinic for the year 2017 was conducted. A MUE using a standardized data collection form was performed on 100 randomly selected folders. Data are summarized using descriptive statistics. Results The majority of cases were women (76) with a mean age of 55.9y (SD12.49). A diagnosis of NP was recorded in 58 folders and a “possible” diagnosis recorded in 7 folders. In 79 cases there was no mention of a tool/method used to diagnose NP. The most common condition diagnosed was chronic post-surgical pain with a neuropathic component (n=16), followed by NP (n=15). The most common initiating and current dose of Pregabalin was 75mg twice daily. In 56 patients, Pregabalin was prescribed in conjunction with a tricyclic antidepressant (TCA) or selective noradrenaline reuptake inhibitor (SNRI). Patient education was documented as having taken place in 76 of cases. Conclusions Based on this MUE we recommend the use of screening tools for the diagnosis of neuropathic pain, and a focus on the initiating dose of Pregabalin. The use of a standardized assessment document and the interdisciplinary team input at this clinic appears to optimize prescribing of Pregabalin in line with practice guidelines.
2

Documentation numérique en Afrique francophone subsaharienne : évaluation de l'offre et des usages en sciences humaines à l'Université Cheikh Anta Diop de Dakar / Digital documentation in Africa : evaluation of the offer and uses in the human sciences of the University Cheikh Anta Diop of Dakar

Kane, Khardiatou 25 September 2018 (has links)
Les bibliothèques universitaires des pays d’Afrique francophone sont confrontées à un défi en matière d’offre documentaire dans un contexte marqué par un manque de moyens financiers, une augmentation des coûts de la documentation, et certaines formes organisationnelles peu efficientes. Cette thèse vise dans un premier temps, à partir d’enquêtes et de recueils de données diversifiées, à dresser l’état de l’offre documentaire papier et numérique à l’Université Cheikh Anta Diop de Dakar, en Sciences humaines et sociales (SHS), tout en soulignant des points de comparaison avec d’autres universités francophones subsahariennes. Les résultats visent à quantifier et à qualifier cette offre, à pointer les nouvelles dynamiques dans le cadre de la documentation numérique avec différents types d’acteurs. Par ailleurs, les bibliothécaires cherchent à s’appuyer pleinement sur l’Open Access tant au niveau de l’accès à des ressources qu’au niveau de la valorisation des fonds locaux. L’information numérique est de plus en plus perçue comme le meilleur moyen de satisfaire les besoins en information de la communauté universitaire de l’Université Cheikh Anta Diop (UCAD) de Dakar. Néanmoins, elle est souvent confrontée à des problèmes d’accès à l’information mais également d’usage des ressources documentaires. Cette recherche s’intéresse, dans une seconde partie, à l’appréciation de l’usage des ressources numériques, une appréciation qui se fera comparativement entre plusieurs disciplines de l’UCAD et entre enseignants et étudiants de ladite université. Des recommandations sont formulées dans la troisième partie pour tenter d’y améliorer les services documentaires. / University libraries in French-speaking African countries face a documentary supply challenge in a context of a lack of financial resources, an increase in the cost of documentation, and some inefficient organizational forms. This thesis aims at first, from surveys and collections of diverse data, to establish the state of the paper and digital documentary offer at the University Cheikh Anta Diop of Dakar, in SHS, highlighting points comparison with other Sub-Saharan Francophone Universities. The results are intended to quantify and qualify this offer, to point out new dynamics in the context of digital documentation with different types of actors. In addition, librarians seek to rely fully on Open Access, both in terms of access to resources and the value of local funds. Digital information is increasingly seen as the best way to meet the information needs of the university community at Dakar's Cheikh Anta Diop University (UCAD). Nevertheless, it is often confronted with problems of access to information but also of use of documentary resources. This research focuses, in a second part, to appreciate the uses of digital resources, in a comparative way between several disciplines at UCAD and between teachers and students. Recommendations are made to try to improve the documentary services in this University.

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