Submitted by Raniere Barreto (raniere.barros@ufvjm.edu.br) on 2018-04-18T18:22:07Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dilceu_silveira_tolentino_junior.pdf: 5803624 bytes, checksum: c8a9428406d9584da986cb951325dbee (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2018-04-20T13:14:03Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dilceu_silveira_tolentino_junior.pdf: 5803624 bytes, checksum: c8a9428406d9584da986cb951325dbee (MD5) / Made available in DSpace on 2018-04-20T13:14:03Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dilceu_silveira_tolentino_junior.pdf: 5803624 bytes, checksum: c8a9428406d9584da986cb951325dbee (MD5) Previous issue date: 2017 / As doen?as autoimunes s?o s?ndromes cl?nicas distintas caracterizadas por v?rias altera??es na resposta imune normal, com perda da toler?ncia para constituintes do pr?prio hospedeiro que representam um importante problema de sa?de p?blica que atinge de 3 a 5% da popula??o mundial. O presente estudo teve como objetivo realizar o levantamento epidemiol?gico de doen?as autoimunes de usu?rios do sistema ?nico de sa?de proveniente da aten??o prim?ria ? sa?de da microrregi?o de sa?de de ?guas Formosas - Minas Gerais, contemplando as caracter?sticas sociodemogr?ficas da amostra, al?m da distribui??o, frequ?ncia e determinantes dessas doen?as no ?mbito dos munic?pios que a comp?em. Trata-se de estudo epidemiol?gico de abordagem quantitativa e delineamento transversal, com a realiza??o de inqu?rito domiciliar do tipo survey, de natureza descritiva e explorat?ria. O estudo foi aprovado pelo Comit? de ?tica em Pesquisa da Universidade Federal dos Vales do Jequitinhonha e Mucuri. O inqu?rito foi realizado de janeiro a dezembro de 2016. Um total de 407 portadores e 24 diferentes doen?as autoimunes foi identificado. A preval?ncia de doen?as autoimunes nesta regi?o foi de 673,6 casos para cada 100.000 habitantes. A maior preval?ncia foi identificada para tireoidite de Hashimoto, seguidas de vitiligo e artrite reumatoide. Em rela??o ao sexo foi maior no feminino (69,25%), confirmando a tend?ncia mundial. A faixa et?ria mais acometida foi de 60 anos e mais (31,21%) com maior predomin?ncia para a zona urbana (81,76%) quando comparada a zona rural. Ao comparar a preval?ncia encontrada com a de estudos anteriores, verificou-se que a preval?ncia de v?rias doen?as na microrregi?o ultrapassou algumas estimativas nacionais e mundiais. O presente estudo ensejou o primeiro levantamento epidemiol?gico e a estimativa da preval?ncia de doen?as autoimunes na microrregi?o de sa?de de ?guas Formosas - Minas Gerais, Brasil, sendo poss?vel atrav?s destas informa??es, auxiliar aos gestores no planejamento das pol?ticas p?blicas de sa?de para esta microrregi?o. / Disserta??o (Mestrado Profissional) ? Programa de P?s-Gradua??o em Tecnologia, Sa?de e Sociedade, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2017. / Autoimmune diseases are distinct clinical syndromes characterized by several alterations in the normal immune response, with loss of tolerance for host constituents that represent a major public health problem that affects 3 to 5% of the world population. The present study aimed to carry out the epidemiological survey of autoimmune diseases of users of the unified health system from the primary health care of ?guas Formosas - Minas Gerais health micro-region, considering the sociodemographic characteristics of the sample, as well as the distribution, frequency and determinants of these diseases within the municipalities that comprise it. This is an epidemiological study and a quantitative approach with a cross-sectional design, with the conduct of a survey-type household survey of a descriptive and exploratory nature. The study was approved by the Research Ethics Committee of the Federal University of the Jequitinhonha and Mucuri Valleys. The survey was conducted from January to December 2016. A total of 407 carriers and 24 different autoimmune diseases was identified. The prevalence of autoimmune diseases in this region was 673,6 cases per 100,000 inhabitants. The highest prevalence was identified for Hashimoto's thyroiditis, followed by vitiligo and rheumatoid arthritis. Sex was higher in the female (69.25%), confirming the world trend. The most affected age group was 60 years and over (31.21%), with a greater predominance in the urban area (81.76%) when compared to rural areas. When comparing the prevalence found with that of previous studies, it was verified that the prevalence of several diseases in the micro-region exceeded some national and world estimates. The present study led to the first epidemiological survey and estimation of the prevalence of autoimmune diseases in the health micro-region of ?guas Formosas - Minas Gerais, Brazil. It is possible through this information to assist managers in the planning of public health policies for this micro-region.