L’angiogenèse ou la mise en place de nouveaux vaisseaux sanguins à partir de vaisseaux préexistants, est indispensable à la croissance tumorale et constitue donc une cible intéressante en thérapie anticancéreuse. Depuis 2004, plusieurs thérapies anti-angiogéniques ciblant les cancers du colon, poumon, sein et rein, ont été développées et sont appliquées en clinique. Le gène VE-statine/egfl7 a été découvert au sein du laboratoire en 2003 et il est majoritairement exprimé par les cellules endothéliales au cours du développement embryonnaire et du remodelage vasculaire. Plusieurs publications ont montré l’implication de la VE-statine dans la formation des vaisseaux. L’expression de la VE-statine par des tumeurs humaines a récemment été décrite, et une forte expression est associée avec un haut grade tumoral, une forte incidence métastatique et un mauvais pronostic dans les hépatocarcinomes, les gliomes et les tumeurs colorectales. L’objectif de ma thèse était de mettre au point les approches et d’étudier les effets de la VE-statine dans la croissance et l’angiogenèse tumorale. Cette analyse permet de mieux comprendre les mécanismes modulant la progression tumorale. / Angiogenesis, which corresponds to the growth of new blood vessels from pre-existing vessels; is necessary for tumor growth and is an attractive target for anticancer therapy. Since 2004, several antiangiogenic therapies against colon, lung, breast, kidney cancers have been developed and used in clinic.VE-statin/egfl7 was discovered by our team in 2003. It is specifically expressed by endothelial cells during embryonic development and vascular remodelling. Several publications have described the role of VE-statin in vessel formation. VE-statin expression by human tumors has been recently associated with a higher grade and metastatic score and with a poorer prognosis in hepatocellular carcinoma, glioma and colorectal cancer.The aim of my work was to develop tools for the study of the functions of VE-statin in tumor growth and angiogenesis. This analysis allows a better understanding of the mechanisms which modulate tumor progression.

This thesis deals with the possibilities of using computers for training teachers of German. The theoretical part addresses the general possibility of using computers by foreign language teachers in their everyday work. The latest trends in education are shown in this part. The practical part focuses on mapping IT skills of future German language teachers, currently studying at university. The last part of the thesis shows various possibilities of using computers in pre-service teachers? training and also brings several worksheets for a ready-prepared sample lesson, designed for teaching in a multimedia computer lab. The conclusion summarizes and evaluates results of the work.

In this thesis I focus on the use of puppets in motion pictures, reasons for their use and their specification within this media. Partly I touch the similar subject in terms of their use in theatre, while describing both the historical context and my own experience. Through examples of my own work I reflect my own different approaches towards puppets that have changed on the ground of my gained experience.

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This diploma thesis has been developed at the Faculty of Horticulture Mendel University in Brno, at the Institute of viticulture and winemaking in Lednice. The thesis deals with the influence of different plant mixtures in the interfaces of vineyard for the intake of nutrient by grapevine. The literary part of the thesis provides an overview of significance of the planting for vineyards, sowing and treatment of the plants. Further the literary part contains description of individual families and plants and indicates in which vineyards are specific plant mixtures usable. The experimental part examines three different plant mixtures and their influence on the intake of macroelements and microelements by grapevine. The experimental part further indicates the parameters of the grapes selected from each plant mixtures

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VENCELIDESOVÁ, Petra: Master's thesis: Visual concept for the feature film "Puppet Syndrome", screenplay by Alena Alova, based on the novel "Petrushka syndrome" by Dina Rubina. Theatre and puppets in world cinematography. Academy of Performing Arts in Prague, Theatre Faculty, Departement of Stage Design. Advisor: Doc. Ing. Arch. MgA. Ondřej Nekvasil. Prague, 2013. The aim of the thesis is to get familiar with what brings the interconnection of theatre and film, and which art mediums can be used for this purpose. By analyzing several films from various cultural backgrounds and epochs, we can gain a more complete picture of how to work with this theme. Also, the thesis examines production design and its effect in the overall atmosphere and concept of the given film. The main part of the thesis is a visual concept of the film "Puppet Syndrome", in which occurs a significantly theatrical performance as one of the main factors in the development of the story.

This thesis is focused on insurance business in Vietnam, life insurance and nonlife insurance market within the frame of past and present development. Important part of this thesis is also description of insurance intermediaries and reinsurance companies that are significant subjects in insurance market. Macroeconomic and sociodemographic conditions, in which insurance market operates, are described in first chapter. Vietnam insurance market is underdeveloped in comparison to European countries. On the other hand this sector is progressively developing and has large potential; especially in case government reforms will continue and will lead to international openness and free market economy in Vietnam.