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Characterization of thesporozoite and eythrocytic stages (SES) proteinLaCrue, Alexis Nichole. January 2007 (has links)
Thesis (Ph. D.)--University of Missouri-Columbia, 2007. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Vita. "December 2007" Includes bibliographical references.
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Toxoplasma gondii in Australian marsupials /Parameswaran, Nevi. January 2008 (has links)
Thesis (Ph.D.)--Murdoch University, 2008. / Thesis submitted to the Faculty of Health Sciences. Includes bibliographical references (leaves 139-154)
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The production of IL-2, IL-4, and TNF-gas in murine leishmaniasisGreen, Lisa J. January 1991 (has links)
Prophylactic administration of the immunosuppressive drug cyclosporine A protects Balb/c mice from fatal Leishmania major infections. It is believed that distinct subpopulations of CD4+ T lymphocytes and their distinctive cytokines may determine susceptibility and resistance to leishmaniasis among inbred strains of mice. CsA may enhance disease resistance in Balb/c mice by modulating these T cell subsets and/or their cytokines. We have measured lymphoid cell production of IL-2, IL-4, and TNF-a in naturally resistant C57/Bl/6, CsA-treated Balb/c, and nontreated Balb/c mice during the course of L. major infection. CsA treatment inhibited IL-2 and IL-4 production for the first week of infection. Thereafter the cytokine production of all three groups of mice did not differ greatly except in week two when the treated mice produced significantly enhanced levels of IL-4. C57B1/6 mice did produce slightly more TNF-a than either group of Balb/c mice, but as the CsAprotected and diseased Balb/c mice produced similar amounts of this cytokine, the elevation in C57B1/6 animals probably reflects a strain-related difference rather than disease resistance. / Department of Biology
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The occurrence of piroplasms in various South African black rhinoceros (Diceros bicornis) populationsZimmerman, David Edwin. January 2010 (has links)
Thesis (MSc (Veterinary Tropical Diseases)--University of Pretoria, 2009. / Includes bibliographical references. Also available in print format.
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Occurence and transmission of Toxoplasma gondii in European starlings (Sturnus vulgaris) of northern CaliforniaHaslett, Theresa Marie 01 January 1977 (has links)
This research was performed to determine; (1) the prevalence of Toxoplasma antibodies among starlings in Northern California, (2) if such starlings can transmit the disease, and (3) if tissues from seropositive starlings contain encysted forms of T. gondii.
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Improved diagnosis of trypanosome infections and drug resistant T.congolense in livestockDelespaux, Vincent F.P. 26 January 2005 (has links)
The aim of this thesis was to provide a picture of the trypanosomosis and drug resistance prevalence in Eastern Province of Zambia, to understand the underlying factors of drug resistance (drug use habits), to improve the diagnosis of trypanosomosis in livestock and finally, to improve the diagnosis of isometamidium resistance in T.congolense. After an introductory part where available trypanosomosis and trypanocide resistance diagnostic methods are described and discussed, the body of the thesis is divided in two main sections. In the first section are presented the results of a cross-sectional and a longitudinal epidemiological survey describing the geographical distribution of trypanosomosis cases, of resistant isolates and of cattle treated with isometamidium chloride. The results of the monitoring of unsupervised treatments of cattle with isometamidium by farmers and veterinary assistants with the Isometamidium-ELISA technique are also presented. The second section describes the development of two new diagnostic methods, the first one allowing the diagnosis of trypanosome infections with high sensitivity and specificity through semi-nested polymerase chain reaction and restriction fragment length polymorphism. This is the first report of a pan-trypanosome PCR test (a single PCR test for the diagnosis of all important pathogenic trypanosomes of cattle). The second new method that was developed allows the diagnosis of isometamidium resistant T.congolense strains by PCR-RFLP. This is the first report of a PCR based diagnostic test of trypanocide resistance in T. congolense.<p> / Doctorat en sciences, Spécialisation biologie moléculaire / info:eu-repo/semantics/nonPublished
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