Yes / Polymerase chain reaction (PCR) has become a powerful tool for detecting various diseases due to its high sensitivity and specificity. However, the long thermocycling time and the bulky system have limited the application of PCR devices in Point-of-care testing. Herein, we have proposed an efficient, low-cost, and hand-hold PCR microdevice, mainly including a control module based on water-cooling technology and an amplification module fabricated by 3D printing. The whole device is tiny and can be easily hand-held with a size of about 110 mm × 100 mm × 40 mm and a weight of about 300 g at a low cost of about $170.83. Based on the water-cooling technology, the device can efficiently perform 30 thermal cycles within 46 min at a heating/cooling rate of 4.0/8.1 ℃/s. To test our instrument, plasmid DNA dilutions were amplified with this device; the results demonstrate successful nucleic acid amplification of the …

In recent years, the electronic chip is continuously developing in turning high performance. This trend urges the heat sink of electronic chip to become gradually important, and then that will develop many type of heat sink, which is water-cooling system. Therefore, the purpose of this paper is designing a high efficiency water-cooling element (WCE). The present study mainly aims at three points to bring up: (1) The different type chamber make use of the CFD package software FLUENT to study the pressure drop, velocity field and turbulent intensity deposition. (2) The different plank thickness, thermal conductivity and convection heat transfer coefficient use finite difference method to solve heat diffusion equation, and to confer thermal resistance value. (3) Then, machined this designed WCE and then measured its thermal resistance value. The results show: (1) The pressure drop main effect parameter is inlet velocity. (2) The thermal resistance value main effect parameter is convection heat transfer coefficient. (3) The plank thickness is inverse proportion relation with thermal resistance value. (4) The surface temperature range and mean surface temperature should become reference index in heat sink developmental process. (5) The cooling performance of Type D WCE is optimum in this paper. (6) The design is cross groove on convection surface, which should reduce thermal resistance value.

Thesis (M.Eng.)(Chemical Engineering)--University of Pretoria, 2006. / Accompanied by a CD-ROM: Appendix B. Cooling tower model results. Includes bibliographical references. Available on the Internet via the World Wide Web.

This thesis deals with computing and experimental problems of direct water cooling of stator winding that is assigned in synchronous motors. A model with similar material characteristic to a real motor has been made for experiments. The computing results showed us the appropriate place for the cooling system. This place has been chosen due to maximum efficiency and cost of the cooling system. The experiments on the model showed us, if the computing results are credible.

This diploma thesis is dealing with the impact of oxide scales on heat conduction. One of the main tools that were used are numerical simulations. Heat conduction is modelled by solving partial differential equations. Regression models and artificial neural networks are used for the prediction of the influence of oxides on cooling intensity. Determination of the conditions when the cooling was intensified and comparison of individual methods of prediction are the main results of the thesis.

The report contains three parts. The first part is a summary and overall presentation of thermal cracks and preventing measures against such cracks. This is a theoretical part where the interested designer can get acquainted with various alternatives, be guided to more detailed literature, and receive some practical information regarding the design of the respective measures. The second part deals with calculation of the risk for thermal cracks and design of water cooling as a limiting measure. Two complementary methods are reviewed for efficient calculation: • the handbook method CraX1 (by Lulea University of Technology) is used for quick verification • finite differential analysis in the calculation tool ConTeSt Pro for more precise projecting Here is also presented a development of existing standards through design of the cooling system by means of the Bernoulli equation. Comparison is made with the approximation with Manning’s formula, which occurs in the field today. The calculation part is concluded with a calculation example. In addition to prescribing good project planning, the example also highlights some of the calculation programs’ possibilities and limitations. The third part of the report evaluates the current calculation of the risk for thermal cracking in young concrete, as well as the design and implementation of thereto related measures. This is done through studies of reference objects and interviews with all parts involved, i.e. clients, consultants, contractors and suppliers. The report aims to a compilation and transfer of skill and experience, so that potential for improvement in the prevention of thermal cracking can be identified, and the design can be improved with regard to the conditions of the construction phase. / Rapporten innehaller tre delar. Den forsta delen utgor en sammanstallning och oversiktlig presentation av temperatursprickor samt forebyggande atgarder mot sadana sprickor. Det ar en teoretisk del dar den intresserade projektoren kan satta sig in i olika alternativ, vagledas till utforligare litteratur, samt fa en del praktisk information infor projekteringen av respektive atgard. Den andra delen avhandlar berakning av risk for temperatursprickor samt projektering av vattenkylning som sprickbegransande atgard. Tva kompletterande metoder gas igenom for effektiv berakning: • handboksmetoden CraX1 (fran Lulea tekniska universitet) for snabbare kontroller • finita differensanalyser i berakningsprogrammet ConTeSt Pro for noggrannare projektering Har presenteras aven en utveckling av nuvarande standarder via dimensionering av kylsystem for vatskekylning med hjalp av Bernoullis ekvation. Jamforelse gors med approximationen med Mannings formel, vilken i dagslaget forekommer i branschen. Berakningsdelen avslutas med ett berakningsexempel. Forutom att foreskriva god projektering, belyser exemplet dessutom nagra av berakningsprogrammens mojligheter och begransningar. Rapportens tredje del utvarderar den nuvarande berakningen av risk for temperatursprickor i ung betong, samt projekteringen och genomforandet av tillhorande atgarder. Detta gors via studier av referensobjekt och intervjuer med samtliga involverade aktorer, d.v.s. bestallare, konstruktorer, entreprenorer och leverantorer. Rapporten syftar till en sammanstallning och aterforing av kompetens och erfarenhet, sa att forbattringspotential i forebyggandet av temperatursprickor kan identifieras, och projekteringen kan forbattras med hansyn till produktionens forutsattningar.

This thesis deal with design and implementation of innovative cooling method, intended primarily for medium-power synchronous generators. The main objective of this proposal is to remove the large heat exchanger connected to generator. This heat exchanger unduly increases the space requirements for the machine location. The proposed solution is to use a direct water-cooled stator. It is assumed that the rotor winding will be still cooled by air. Unlike current cooling system, the hot air from the rotor can be cooled in smaller cooler inside the generator. In this work are described methods which can be used for design of water cooling basic parameters, taking required temperatures into account. A small induction motor was selected for practical verification of the proposed cooling concept. This motor was modified into two variants - related to the old cooling of synchronous generators and related to the proposed solution. Both of these variants were measured and compared with each other. Subsequently, CFD models of these two variants were set up. Measured temperatures were used for debugging of models and identification of material properties of components of these machines. The final model of water-cooled variant also makes it possible to simulate the work of motor for higher performance and to determine the overload compared with the old cooling variant. Some knowledge and experience obtained from the small water-cooled induction machine were used in the design of water-cooling for large synchronous generator. In a similar way, CFD models of the old variant of cooling and proposed variant of water- cooling were created. Although these models were not verified by actual measurements on the generators, the results indicated that the application of water-cooling in this type of machine is appropriate and provides many benefits.

The diploma thesis is focused on creation of a business plan for establishing a new company. Company makes a new computer sets with water cooling system and own design. The analysis of internal and external environment of the company and particular bisuness plan, are based on theoretical part resources.

This thesis deal with design and implementation of innovative cooling method, intended primarily for medium-power synchronous generators. The main objective of this proposal is to remove the large heat exchanger connected to generator. This heat exchanger unduly increases the space requirements for the machine location. The proposed solution is to use a direct water-cooled stator. It is assumed that the rotor winding will be still cooled by air. Unlike current cooling system, the hot air from the rotor can be cooled in smaller cooler inside the generator. In this work are described methods which can be used for design of water cooling basic parameters, taking required temperatures into account. A small induction motor was selected for practical verification of the proposed cooling concept. This motor was modified into two variants - related to the old cooling of synchronous generators and related to the proposed solution. Both of these variants were measured and compared with each other. Subsequently, CFD models of these two variants were set up. Measured temperatures were used for debugging of models and identification of material properties of components of these machines. The final model of water-cooled variant also makes it possible to simulate the work of motor for higher performance and to determine the overload compared with the old cooling variant. Some knowledge and experience obtained from the small water-cooled induction machine were used in the design of water-cooling for large synchronous generator. In a similar way, CFD models of the old variant of cooling and proposed variant of water- cooling were created. Although these models were not verified by actual measurements on the generators, the results indicated that the application of water-cooling in this type of machine is appropriate and provides many benefits.

Neste trabalho foi realizada a modelagem fenomenológica do desempenho de uma torre de resfriamento de água e de um sistema de duas torres de resfriamento em série, com temperatura de água de entrada de até 65 ºC. Verificou-se a validade do modelo através de comparação dos resultados previstos com os obtidos em ensaios em uma unidade piloto. Em seguida, através de simulação matemática, a partir do modelo desenvolvido, foi feito o estudo de diversos casos de aplicação. Estudou-se a influência das principais variáveis de operação (vazão de ar, vazão de água e temperatura de bulbo úmido) no desempenho de torres de resfriamento acopladas (em série e em paralelo) e no custo operacional. Verifica-se que a variável de maior influência é a vazão de água que circula pela torre. / This is a study about the phenomenological modeling of the performance of a water cooling tower and a system of two cooling towers in series, with water temperature input up to 65°C. The validity of model was verified by comparing the expected results with those obtained in tests on a pilot plant. After this, through a mathematical simulation, based on the model developed, several cases of application were analyzed. It was studied the influence of main operating variables (air flow, water flow and wet bulb temperature) on the performance of couples cooling towers (in series and parallel) and on operational cost. It was verified the most influential variable is the water flow rate through the tower.