Background: Age-related changes in pelvic floor muscle (PFM) biomechanics may contribute to urinary incontinence in older women; however, empirical evidence is scant. Purpose: This study aimed to understand the age-related changes in the biomechanical properties of the PFMs in women with no major risk factors for urinary incontinence. Methods: Thirty-three nulliparous women (20-64 years) were recruited to study active force, rate of force development, endurance, resistance to passive stretch and stiffness properties of the PFMs using an automated dynamometer. Separate regression analyses were performed to investigate the relationship between age and each outcome measure. Results: No significant relationships were observed between age and any of the outcome measures. Conclusion: The findings from this study do not support the presence of any age-related changes in PFM mechanics among women aged 20-64. Recruiting women over the age of 65 may be essential to detect age-related changes in PFM biomechanics in nulliparous women.

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René Descartes’ 1637 “bête machine” characterization of nonhuman animals has assisted in the strengthening of the Genesis 1:26 and 1: 28 disparate categorization of nonhuman animals and human animals. That characterization appeared in Descartes’ first important published writing, the Discourse on the Method, and can be summarized as including the ideas that nonhuman animals are like machines; do not have thoughts, reason or souls like human animals; and thus, cannot be categorized with humans; and, as a result, do not experience pain or certain other feelings. This characterization has impeded the primary objective of environmental ethics - the extension of ethical consideration beyond human animals - and has supported the argument that not only the nonhuman animal but also the rest of nature has only instrumental worth/value. As is universally recognized, Gottfried Wilhelm Leibniz, just a few decades after Descartes’ death, took issue with Descartes’ dualism by arguing that the Leibnizian monad, with its active power, was the foundation of, at least, all of life. This argument must result in the conclusion that nonhuman and human animals are necessarily categorized collectively, just as Charles Darwin later argued. In fact, when the writings of Descartes and Michel de Montaigne are reviewed, it becomes apparent that Descartes never believed his bête machine characterization but embraced it to achieve not only his philosophical objectives but also his anatomical and physiological objectives. Philosophically, Descartes was answering Montaigne’s skepticism and his use of nonhuman animal examples to discredit human reason. Also, Descartes spent a major part of, at least, the last twenty-two years of his fifty-four year life dissecting nonhuman animals. Finally, the role that the politics and policies of the Christian institutions played in these matters is of primary importance. Similar politics and policies of the Christian institutions have since played, and still play, an important role in the continuing, unreasonable, disparate categorization of human animals and nonhuman animals. Philosophy seems to be the only discipline that can, if it will, take issue with that characterization.

Diplomová práce se zabývá představením, popisem a vytvořením modelu postranní řídicí páky pilota s aktivní silovou zpětnou vazbou firmy Honeywell International Inc. v prostředí MATLAB Simulink. Dále pak představením problému pilotem indukovaných oscilací a možnostmi jejich předcházení, detekce a potlačení. Model řídicí páky se silovou zpětnou vazbou je použit pro potlačení detekovaných oscilací v simulaci letounu.