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Background: Cognitive impairment and cannabis use are common among patients with schizophrenia. However, the moderating role of cannabis on cognition remains unclear. Aim: We sought to examine cognition and symptomatology as a function of cannabis use patterns in schizophrenia. Methodology: Cognition was assessed in male outpatients with current cannabis dependence (n=18), historical cannabis dependence (n=21) and patients with no lifetime use (n=8). In addition, we explored the relationship between cumulative cannabis exposure and cognition among lifetime users. Results: Lifetime cannabis users demonstrated better processing speed than patients with no lifetime use. Notably, patients with current dependence exhibited robust relationships between cumulative cannabis exposure and cognition; associations were absent in former users. Conclusions: Cannabis status has minimal effects on cognition in schizophrenia. However, cumulative cannabis exposure significantly impairs cognition in current, but not former users, suggesting that the state dependent negative effects of cannabis may be reversed with sustained abstinence.

Background: Cognitive impairment and cannabis use are common among patients with schizophrenia. However, the moderating role of cannabis on cognition remains unclear. Aim: We sought to examine cognition and symptomatology as a function of cannabis use patterns in schizophrenia. Methodology: Cognition was assessed in male outpatients with current cannabis dependence (n=18), historical cannabis dependence (n=21) and patients with no lifetime use (n=8). In addition, we explored the relationship between cumulative cannabis exposure and cognition among lifetime users. Results: Lifetime cannabis users demonstrated better processing speed than patients with no lifetime use. Notably, patients with current dependence exhibited robust relationships between cumulative cannabis exposure and cognition; associations were absent in former users. Conclusions: Cannabis status has minimal effects on cognition in schizophrenia. However, cumulative cannabis exposure significantly impairs cognition in current, but not former users, suggesting that the state dependent negative effects of cannabis may be reversed with sustained abstinence.

Thesis (B.A.)--Haverford College, Dept. of Religion, 2007. / Includes bibliographical references.

Thesis (Ph. D.)--Virginia Commonwealth University, 2007. / Prepared for: Dept. of Psychology. Bibliography: leaves 106-118. Also available online.

Thesis (Ph.D.)--Bowling Green State University, 2008. / Document formatted into pages; contains vii, 75 p. Includes bibliographical references.

Thesis (B.S.H.N.)--Regis University, Denver, Colo., 2009. / Title from PDF title page (viewed on May 22, 2009). Includes bibliographical references.

Thesis (M.A.)--Rowan University, 2008. / Typescript. Includes bibliographical references.

Thesis (M.S.)--University of Wisconsin--Madison, 1965. / eContent provider-neutral record in process. Description based on print version record. Bibliography: l. 113-118.

Thesis (M.D.)--University of Hong Kong, 1972. / Also available in print.