Thesis (M.S.)--University of Michigan, 1999. / Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1999. / Includes bibliographical references.

Thesis (M.S.)--University of Southern California, 1997. / eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1989.

Thesis (M.S.)--University of Southern California, 1997. / Includes bibliographical references.

Thesis (M.S.)--University of Michigan, 1989.

Thesis (M.S.)--University of Tennessee Health Science Center, 2006. / Title from title page screen (viewed on October 8, 2007 ). Research advisor: Edward Harris, Ph.D. Document formatted into pages (xiii, 156 p. : ill.) Vita. Abstract. Includes bibliographical references (p. 137-147).

Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.

An age-related attenuation of the normal increase in diastolic blood pressure and heart rate upon standing has previously been observed in man. Whether this is due to aging as such or is a consequence of a higher prevalence of cardiovascular disease in older compared to younger subjects is unclear. This population-based study addresses this question and presents the blood pressure and heart rate responses to sudden changes in body position in representative groups of men aged 30 (n=50), 50 (n=44) and 60 (n=69) years, as well as in 60-year-old men with hypertension (n=75) or previous myocardial infarction (n=39) and in a control group (n=41) free from these diseases. Blood pressure and heart rate were measured during three seven-minute periods (supinestanding-supine), using an unbiased non-invasive method. Whereas there was an initial decrease in systolic blood pressure upon standing in men aged 50 and 60 years, an increase was seen in the 30-year-olds. The diastolic blood pressure increased in all age groups, but less in the older compared to the younger men. In all age groups, the change in systolic blood pressure upon standing was transient, while the changes in the diastolic blood pressure lasted during the entire observation period. The heart rate increased to a similar extent upon standing in all age groups. After resuming the supine position, both blood pressure and heart rate returned to the levels initially recorded. The cardiovascular responses were both qualitatively and quantitatively similar in all three groups of 60-year-old men (with or without hypertension or previous myocardial infarction). In conclusion, this population-based study confirmed previous observations of an age-related attenuation of the blood pressure response to change in body position. However, 60-year-old men with hypertension or previous myocardial infarction had blood pressure responses similar to those of men of the same age and free from these diseases. This indicates that the attenuated response in older compared to younger subjects is not explained by the higher prevalence of these cardiovascular diseases in the elderly, but appears to be the result of normal aging.

Made available in DSpace on 2014-06-11T19:25:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-08-28Bitstream added on 2014-06-13T18:29:10Z : No. of bitstreams: 1 sabino_aj_me_araca.pdf: 203707 bytes, checksum: 2e1c3c45b12f8f08080a961981b5bb46 (MD5) / Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) / Objetivou-se obter valores eritrocitários de referência para avestruzes criados em sistema comercial na Região de São José do Rio Preto, São Paulo, Brasil. Para tal foi padronizada a forma de colheita de sangue, comparando o efeito de dois diferentes anticoagulantes (ácido etilenodiaminotetracético sódico - EDTA e heparina sódica) na morfometria e integridade dos eritrócitos permitindo concluir que, para fins de análises quantitativa e morfométrica dos parâmetros eritrocitários de avestruzes, a heparina sódica (10 U/mL sangue) é um anticoagulante mais adequando do que o EDTA sódico (2 mg/ mL sangue). Foram analisadas 240 amostras de sangue heparinizadas de avestruzes de ambos sexos, divididos em três diferentes faixas etárias: 4├13meses; 13 ├ 22 meses e 22 ├ 30 meses. Utilizando-se método analítico padrão, verificou-se que os valores de eritrócitos, hemoglobina, hematócrito, volume corpuscular médio (VCM), hemoglobina corpuscular média (HCM), concentração da hemoglobina corpuscular média (CHCM), o diâmetro maior e menor dos eritrócitos sofrem influência do sexo (fêmeas) e faixa etária. Concluiu-se deste estudo que para adequada interpretação clínica dos valores eritrocitários dos avestruzes deve-se levar em consideração o tipo de anticoagulante utilizado para obtenção da amostra e valores de referência que considere as particularidades do sexo e da idade. / The aim of this study was to obtain the reference values of erythrocyte indices for ostriches raised in a commercial system in the region of São José do Rio Preto, São Paulo State, Brazil. To achieve the purpose of the study, we standardized a blood specimen collection comparing the effect of two different anticoagulants such as Ethylenediaminetetraacetic Acid sodium (EDTA) and Heparin sodium on the erythrocyte morphometry and integrity, which made possible to conclude that for the purposes of quantitative and morphometric analyses of the erythrocyte parameters of ostriches, the heparin sodium (10 U/mL of blood) is a much more appropriated anticoagulant than the EDTA sodium (2 mg/mL of blood). We analyzed 240 heparinized blood samples of both male and female ostriches divided into different age groups: 4 ├ 13 months; 13 ├ 22 months; and 22 ├ 30 months. Using a standard analytical method it was observed that the erythrocytes, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH); mean corpuscular hemoglobin concentration (MCHC) values, and both the greater and the smaller diameters of the erythrocytes are under the influence of gender and age group. It was concluded that to have an appropriate clinical interpretation of the erythrocyte indices of the ostriches it should be taken into account the type of the anticoagulant used to obtain the sample and the reference values considering the peculiarities of ostriches’ gender and age.