O objetivo deste trabalho foi delimitar índices de rentabilidade, tais como Taxa Interna de Retorno - TIR, Valor Presente Líquido - VPL e payback, para duas alternativas de traçado de alcoodutos selecionadas pela equipe do trabalho de UNICA et al. (2006), além de analisar se tais projetos são economicamente viáveis diante das demais alternativas de investimentos disponíveis aos agentes envolvidos. Um importante exercício foi a análise de sensibilidade do projeto à alteração de variáveis tais como valor dos investimentos, tarifa e volume captado pelo duto. Foi realizada, ainda, uma comparação entre os índices de rentabilidade obtidos no trabalho de UNICA et al. (2006) e aqueles calculados nesta dissertação. Os principais dados necessários à análise de viabilidade das alternativas selecionadas (Dutovias Conchas/ Paulínia/Campo Limpo/Santos e Conchas/Paulínia/São Sebastião) tais como extensões dos dutos, investimentos necessários, período do projeto, início das operações, tarifa cobrada pelo transporte do etanol, capacidade dos dutos, gastos com operação e manutenção e custo de capital também foram obtidos do trabalho de UNICA et al. (2006). Diante dos dados obtidos, o método escolhido para a avaliação do investimento foi o do Fluxo de Caixa Descontado FCD. Os resultados obtidos sinalizaram que diante da estrutura de investimentos, tarifa dutoviária e capacidade modular dos dutos estabelecidos inicialmente para os projetos pela equipe da UNICA, nenhum dos traçados selecionados apresenta índices de rentabilidade satisfatórios em relação à realidade de mercado. Portanto, pode-se concluir que para projetos dessa natureza, que são essenciais para o desenvolvimento da infraestrutura econômica do Brasil, são realmente necessários subsídios por parte do governo, além da participação massiva da iniciativa privada, caracterizando a necessidade de Parcerias Público-Privadas PPP. / The goal of this work was to delimit profitability indexes, as such Internal Rate of Return IRR, Net Present Value NPV and payback, for two alternatives of ethanol pipelines grids selected by UNICAs et al. (2006) working group, and to analyze if these projects are economically feasible in comparison with other investment alternatives that are available for the involved agents. The sensitivity analysis of the project in relation to some variables changes, as the investment values, tariff and volume transported through the pipeline, was an important exercise. It was also done a comparison among the resulting profitability indexes of UNICAs et al. (2006) work and those calculated in this dissertation. The main data necessary to the feasibility analysis of the selected alternatives (Conchas/Paulínia/Campo Limpo/Santos and Conchas/Paulínia/São Sebastião pipelines) as pipelines extension, necessary investments, project period, start of operations, charged tariff for ethanol transportation, pipelines capacity, operations and maintenance spending and cost of capital was also obtained in UNICA et al. (2006) work. Considering the available data, the Discounted Cash Flow DCF method was selected to make the investments evaluation. The results indicate that, considering the investment structure, pipeline tariff and modular capacity of the pipelines initially determined to the projects by UNICAs team, none of the selected grids have satisfactory profitability indexes in relation to market reality. So, it is possible to conclude that, in case of projects of this nature, which are essential to the economic and infrastructure development in Brazil, governmental subsidies are necessary, in addition to private initiative massive participation, characterizing the need of Public- Private Partnerships - PPP.

This diploma thesis concerns the possibilities of financing culture from the European funds. The aim is to identify specific programs, which can help with the funding of the cultural sector. Moreover, the thesis includes a written feasibility study on a particular project, which is the reconstruction of a national cultural monument. Another part included proposes several cultural events that are appropriate for this project. Finally, the thesis evaluates the current possibilities of financial support for cultural actors. It also evaluates the eligibility of the project to receive financial support.

Background: A pilot study can be an important step in the assessment of an intervention by providing information to design the future definitive trial. Pilot studies can be used to estimate the recruitment and retention rates and population variance and to provide preliminary evidence of efficacy potential. However, estimation is poor because pilot studies are small, so sensitivity analyses for the main trial's sample size calculations should be undertaken. Methods: We demonstrate how to carry out easy-to-perform sensitivity analysis for designing trials based on pilot data using an example. Furthermore, we introduce rules of thumb for the size of the pilot study so that the overall sample size, for both pilot and main trials, is minimized. Results: The example illustrates how sample size estimates for the main trial can alter dramatically by plausibly varying assumptions. Required sample size for 90% power varied from 392 to 692 depending on assumptions. Some scenarios were not feasible based on the pilot study recruitment and retention rates. Conclusion: Pilot studies can be used to help design the main trial, but caution should be exercised. We recommend the use of sensitivity analyses to assess the robustness of the design assumptions for a main trial.

The thesis in theoretical part deals with factors affecting the real estate market in the Czech Republic and their development. It also describes the various phases of a development project and possible ways of financing. The aim is to develop a feasibility study for a residential housing project and a description of all the stages from birth thoughts in my head developer to the final investment. The paper examines the strengths and weaknesses of the business plan and describes all the tasks associated with it. At the end of the examination investor should find a clear answer whether it is appropriate to implement the project or terminate it at an early stage.

The aim of this thesis is to describe and defend ‘The Constraint-Based View’, which is a particular conception of the nature of, and relationship between, ideal and non-ideal theories of justice. Traditionally, ideal theory is characterised by the assumption of ‘full compliance’, while non-ideal theory is characterised by the assumption of ‘partial compliance’. In other words, ideal theories assume that those for whom the theory is meant to apply will be entirely willing and able to comply with the theory’s requirements, while non-ideal theories do not. In Chapter 1 of this thesis, I describe and assess this original conception as well as several alternative accounts of ideal and non-ideal theory, in order to offer a broad survey of the existing literature, and to identify the various ways that these conceptions fail to capture fully the relationship between ideal and non-ideal theory. In Chapter 2, I draw a distinction between two different approaches to theorising about justice. ‘Axiological’ or ‘A-Type’ approaches are characterised by the fact that they include almost no assumptions as inputs to the theory, and that they are not intended to provide action-guiding recommendations as part of the outputs of the theory. In contrast, ‘Practical’ or ‘P-Type’ approaches include additional assumptions as part of their inputs and are intended to form part of a process that ultimately produces action-guiding recommendations. In Chapter 3, I describe and defend my preferred conception of the relationship between ideal and non-ideal theory – the ‘Constraint-Based View’ (CBV). According to the CBV, there is a spectrum of theoretical approaches that can be more or less ideal, depending on the extent to which they include ‘soft constraints’ as part of the inputs to the theory. Soft constraints are facts about the world that can be changed, in contrast to hard constraints, which are facts about the world that cannot. I argue that this way of thinking about the relationship between ideal and non-ideal theory is more useful than the alternative conceptions considered in Chapter 1. In Chapter 4, I examine the roles that feasibility considerations should play in ideal and non-ideal theory, from the perspective of the CBV and in Chapter 5, I explain the implications of adopting the CBV for what I call ‘transitional theory’, which is concerned with the transition from the status quo towards a more ideal state of affairs. In Chapter 6, I offer an example of the CBV in action, by considering its implications for the debate over duties of justice towards future generations.

The aim of this study to analyze if planned project is suitable for implementation in terms of economic, technical, personnel and other factors. Practical experiences of implementation of other project, company and market analysis was used for predictions. The most famous marketing analysis was used to explore the new market and establish marketing strategy. Decision about implementation will based on all acquired data. Project does not require large investment and there is not any big risk for realization.

There is the high saturation of markets in this turbulent time. In common with the competition are markets like an impregnable fortress. So the words like segmentation, targeting and positioning have been playing the key role during selection of required market. The aim of submitted work is to value the efficiency of implemented plan. The point is about branch establishing and its retrospective evaluation of Feasibility Study. This step will be done with some analysis and factors. The last episode will be the part of recommendation for getting it better.

With a continued worldwide trend in population shift from rural to urban areas predicted to increase, new approaches to agricultural production must be considered and implemented. Little academic interest has been applied to determining economically viable urban agriculture crop production sites for business investment. A feasibility model to aid investors in selecting appropriate sites for the development of urban agriculture food production within population centers was created. Lettuce crop trials were performed from August 2015 to December 2015 at the University of Arizona Controlled Environment Agriculture Center to validate the productivity of a unique high density hydroponic system designed for the rooftop environment. The feasibility model is based on this system and with a minimal number of inputs, ranging from size of growing space to growing media costs, determines a wide range of useful outputs. These outputs include crop productivity within the facility, material inputs and a cost breakdown of starting a new agricultural venture. The model utilizes multiple sheets within one excel document to give the user a clear and organized financial perspective of a hypothetical growing operation in the main sheet. With this model, investors into urban agriculture will have a means to gain an objective view of financial considerations before substantial investment is completed.

Orientador: Luciana Patrícia Fernandes Abbade / Resumo: Introdução: Estudos pilotos e de viabilidade são realizados em diversas áreas clínicas e têm importante papel no planejamento e desenvolvimento de ensaios clínicos aleatorizados (ECAs). Entretanto, na literatura existe grande número de ECAs declarados como pilotos e de viabilidade, mas não relatam claramente em seus objetivos e métodos quais itens são testados quanto aos processos e viabilidade e se são uma preparação para estudos maiores. Objetivos: avaliar a adequação dos relatos de ECAs denominados como pilotos ou de viabilidade publicados na área de dermatologia, em relação aos cincos pontos-chaves necessários para relato destes estudos e determinar quais são os fatores associados com adequação completa aos cincos pontoschaves. Métodos: pesquisa sistemática metodológica de ECAs pilotos e de viabilidade em dermatologia publicados no PubMed, no período de janeiro de 2012 a julho de 2018. Critérios de exclusão: protocolos, carta aos editores e estudos pilotos não aleatorizados. A extração de dados de cada artigo selecionado foi realizada por meio de uma planilha padronizada. Dois revisores extraíram os dados e qualquer desacordo foi resolvido através de consenso. Os estudos incluídos foram avaliados quanto sua adequação aos cincos pontos-chaves, os quais foram escolhidos pelos autores a partir do CONSORT Statement para estudos pilotos e de viabilidade, por considerarem que são itens fundamentais para um bom relato de ECA piloto e de viabilidade. Os cincos pontos-chaves são: ... (Resumo completo, clicar acesso eletrônico abaixo) / Abstract: Background: Pilot and feasibility studies are carried out in several clinical areas and have an important role in the planning and development of randomized clinical trials (RCTs). However, in the literature there are a large number of RCTs declared as pilots and viability, but not clearly related in their objectives and methods. What are the items tested with regard to processes and feasibility and if it is a preparation for larger studies. Objectives: to assess RCT’s suitability reports referred to as tests or feasibility of publication in the field of dermatology, in relation to the values of key keys used for study reports and wich are the factors associated with complete adequacy to the key points. Methods: systematic survey of dermatology pilot’s RCT published in PubMed from January 2012 to July 2018. Exclusion criteria: protocols, letter to editorials and non-randomized pilot studies. Data extraction from each selected article was performed using a standardized spreadsheet. Two reviewers extracted the data and any disagreements were resolved by consensus. The included studies were assessed as to their suitability for the five key points, which were chosen by the authors from the CONSORT Statement for pilot and feasibility studies, as they consider that they are fundamental items for a good report of pilot and feasibility RCTs. The five key points are: i) title or abstract indicating that it is a pilot study; ii) objectives attesting to viability; iii) outcomes that ass... (Complete abstract click electronic access below) / Mestre

abstract: Background: Unmanaged stress is a major contributing factor to the development of disease in both men and women. Middle-aged adults (40-64) have some of the highest stress of all age groups and the use of meditation may provide relief for conditions such as stress. A smartphone application (app) may help limit the magnitude of the perceived challenges of meditation. The purpose of this study is to determine the feasibility of a consumer-based meditation app (i.e., Calm) to reduce stress in middle-aged adults who self-report elevated stress. The preliminary effects of Calm on stress and health outcomes related to stress were explored as well as the preliminary effects of Calm on mindfulness and coping behaviors for stress were explored. Methods: Adults were recruited to a 4-week app-based health and well-being study. Participants were randomized into either a mindfulness meditation (i.e. Calm) group or a health education (POD) control group. Participants were asked to participate at least 10 minutes per day. Assessments were conducted for stress, anxiety, depression, mindfulness, physical activity, eating habits, and coping behaviors at pre- and post-intervention and voluntary phone interviews were held post-intervention. App usage data were collected subjectively through weekly participation logs and through objective app usage data provided by Calm. Results: Eighty-three participants were enrolled into the study and 60 completed the intervention and were analyzed. Feasibility and demand benchmarks were met with 96% of participants satisfied with the intervention and 93% found it enjoyable, appropriate, and useful. There was a 70% adherence (minutes/week) to the meditation intervention. Recruitment of men into the intervention group was 38.1% and retention of men was 81.3%. Significant changes were not observed in stress, anxiety, depression, or mindfulness, physical activity, eating habits, and coping behaviors. Conclusion: The findings of this study support the feasibility of a 4-week, mobile app-based mindfulness meditation intervention (i.e. Calm) in middle-aged adults. These finding do not demonstrate preliminary efficacy of Calm to reduce stress, anxiety, and depression or improvement of mindfulness, physical activity, eating habits, or coping behaviors among middle-aged adults who report elevated stress. These results can be applied for improved design of future studies. / Dissertation/Thesis / Masters Thesis Behavioral Health 2020