Thesis (M.S.)--Ohio University, November, 2003. / Title from PDF t.p. Includes bibliographical references (leaves 61-68)

Thesis (MScBosb)--University of Stellenbosch, 2005. / Bibliography. Also available via the Internet.

Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.

Thesis (Ph. D.)--West Virginia University, 2007. / Title from document title page. Document formatted into pages; contains ix, 126 p. : ill. (some col.), col. map. Vita. Includes abstract. Includes bibliographical references.

Thesis (Ph. D.)--University of Texas at Austin, 2007. / Vita. Includes bibliographical references.

Thesis (MA(Social Work Management))--University of Pretoria, 2006. / Includes bibliographical references. Mode of access :World Wide Web.

This report addresses the use of computer-aided software engineering (CASE) technology for the development of aircraft software. / Lean Aerospace Initiative

Mammalian cell culture is typically operated at the physiological temperature of 37°C. Low temperature cell culture at 30-33°C, in particular for CHO cells, increased the specific productivity of many recombinant proteins amongst many other benefits. However, the cell density is lower, thus reducing the total protein yield. Of the 17 mammalian cold-stress genes reported to be up- or down-regulated at low temperature, CIRP shows potential as a gene target for improving recombinant protein production, as its expression levels were reported to affect both growth and specific productivity. In this study, it was shown that over-expression of the cold-stress gene CIRP did not cause growth arrest in CHO cells, in contrast to previous reports. However, over-expression of CIRP successfully improved the specific productivity and total yield of a recombinant interferon-γ CHO cell-line at 37°C by 25%. / Singapore-MIT Alliance (SMA)

Orientador: Arthur Bernardes Cecílio Filho / Banca: Sebastião Wilson Tivelli / Banca: José Carlos Barbosa / Resumo: Na UNESP, Câmpus de Jaboticabal, SP, no período de 19 de maio a 17 de setembro de 2008, foi realizado um experimento com o objetivo de avaliar o efeito de espaçamentos entre linhas e entre plantas sobre o desenvolvimento e a produtividade do repolho roxo. O experimento foi instalado em delineamento em blocos ao acaso, com os tratamentos em esquema fatorial 4 x 3, e três repetições. Foram avaliados os espaçamentos entre linhas: 0,40; 0,60; 0,80 e 1,00 m e os espaçamentos entre plantas: 0,30; 0,40 e 0,50 m. Os teores de N, P e B da folha diagnóstica não foram influenciados pelos fatores. O teor de potássio variou em função do espaçamento entre linhas. O ciclo médio foi de 122 dias, e não foi influenciado pelos espaçamentos. À medida que diminuíram os espaçamentos entre linhas e/ou entre plantas houve redução do número de folhas por planta, área foliar, massa seca das folhas externas à cabeça, massa fresca da cabeça, diâmetro transversal e diâmetro longitudinal da cabeça, comprimento do coração e do índice de formato. O índice de área foliar e a produtividade foram diminuídos quando os espaçamentos entre linhas e/ou entre plantas foram aumentados. A maior produtividade foi de 4,56 kg/m2 e foi observada no espaçamento 0,61 m entre linhas e 0,30 m entre plantas. A menor produtividade de 2,70 kg/m2 foi observada com espaçamento entre linhas de 1,00 m e espaçamento entre plantas de 0,50 m. / Abstract: Viewing to attain information based on research, an experiment was conducted from May 19 through September 17, 2008, in Jaboticabal, state of São Paulo, Brazil, in which the following distances were submitted to analysis: 0.40, 0.60, 0.80, and 1.00 m between rows and 0.30, 0.40, and 0.50 m between plants. The experimental design in the field was that of a randomized complete block in which the treatments were arranged according to a 4 X 3 (four distances between rows and 3 distances between plants) factorial. N, P, and B leaf contents were not affected by the plant arrangements. K content varied as a function of the distance between rows. Plant medium cycle was of 122 days and neither was affected by spacing values. Reducing spacing between rows or between plants resulted in reductions in number of leaves per plant, leaf area, dry matter of leaves outside the head, head fresh weight, the head longitudinal and transversal diameters, the heart length, and the format index of head. Leaf area index and productivity decreased as the distances between rows and/or between plants increased. The largest yield - 4.56 kg/m2 - was observed when the distance between rows of 0.61 m was combined with that of 0.30 m between plants. The lowest production - 2.70 kg/m2 - resulted from the spacing combination of 1.00 m between rows and 0.50 m between plants. / Mestre

Resumo: O trabalho foi realizado no município de Jaboticabal, SP (575 m de altitude, 21°15΄ 22˝ S e 48° 15΄ 58˝ W), tendo como objetivo verificar o efeito de doses de nitrogênio (uréia) e de esterco de bovino no estado nutricional, crescimento e produtividade de rabanete. O delineamento experimental foi blocos ao acaso, em esquema fatorial 2x4x4, com três repetições. Os tratamentos resultaram da combinação dos fatores cultivar (25 e 19), doses de esterco (0, 25, 50 e 75 t ha-1 em base seca) e doses de N (0, 60, 120 e 180 kg ha-1). O aumento nas doses de esterco e de N proporcionaram maiores altura de planta, área foliar, massa fresca e seca de raízes e produtividade comercial de ambas as cultivares, mas com maior contribuição do N do que do esterco. A máxima produtividade comercial da cv. 19 (20,3 t ha-1) foi obtida com 75 t ha-1 de esterco e 139 kg ha-1 de N, enquanto da cv. 25 (11,9 t ha-1) com 75 t ha-1 de esterco e 180 kg ha-1 de N. As doses de máxima eficiência econômica observadas para a cv. 25 foram 65,1 t ha-1 e 180 kg ha-1 de esterco e N, respectivamente, enquanto para a cv. 19 foram 63,6 t ha-1 e 144,7 kg ha-1 de esterco e N, respectivamente. / Abstract: This work was carried out in Jaboticabal, SP (575 m of altitude, 21°15΄ 22˝ S and 48° 15΄ 58˝ W) aiming verify nitrogen (urea) and cattle manure doses effect in the radish nutritional status, growth and productivity. The experimental design used was the randomized blocks within a 2x4x4 factorial scheme, 3 replications. The treatments resulted from the following combination: cultivars (25 and 19), cattle manure doses (0, 25, 50, and 75 t ha-1 dry basis) and N doses (0, 60, 120 and 180 kg ha-1). The increasing cattle manure and urea doses provided higher plant height, leaf area, root fresh and dry mass and commercial productivity in both cultivars, N contributing more than the cattle manure though. The cv 19 maximum commercial productivity (20.34 t ha-1) was obtained using 75 ton ha-1 of cattle manure and 139 kg ha-1 of N. to the cv 25 (11.90 t ha-1) with 75 t ha-1 of cattle manure and 180 kg ha-1 of N. The maximum economic efficiency dose observed to cv 25 were 65.1 t ha-1 and 180 kg ha-1 of cattle manure and N, respectively, while to cv 19 were 63.6 t ha-1 and 144.7 kg ha-1 of cattle manure and N, respectively. / Orientador: Arthur Bernardes Cecílio Filho / Coorientador: Edson Luiz Mendes Coutinho / Banca: Renato de Mello Prado / Banca: Joaquim Gonçalves de Pádua / Mestre