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Call number: LD2668 .T4 1965 K94 / Master of Science

The fractal dimension of the phase space representation of the EEG of 8 clinical patients undergoing general anesthesia is determined. An attempt is made to correlate the trends in EEG dimensional complexity with the depth of anesthesia. While the EEG showed marked changes in dimensional complexity when passing through anesthetic stages, a uniform depth-dimension trend consistent with the eight patients was not observed. The only significant trend observed was a distinct change in dimension for individual EEG's with anesthesia. The dimensional complexities measured were very high and non-convergent, so that the presence of a fractal attractor in the EEG was not evident in this analysis. The observed trends were the close correlation of both brain hemispheres simultaneously exhibiting the same degree of dimensional complexity, and the close correlation of change in EEG spectral edge frequency with change in dimension with anesthesia.

This study was designed to evaluate the efficacy and safety of intranasal sufentanil/midazolam [S/M] and ketamine/madazolam [K/M] for sedation and analgesia in preschool children that require dental surgery [extractions].<br /> <br /> Fifty children [ASA 1] aged 5 &ndash / 7 years, requiring six or more dental extractions under general anaesthesia, were allocated to two groups of 25 children to receive either ketamine 5 mg/kg or sufentanil 20&mu / g intranasally, 20 minutes before induction of surgery in this randomised double-blind study. All the children in both groups in addition concurrently received nasal midazolam 0,3 mg/kg. For induction of anaesthesia, sevoflurane in nitrous oxide and oxygen, was used.<br /> <br /> S/M was accepted significantly better as a nasal pre-medication [p&lt / 0.05]. Both groups were equally sedated and a smooth mask induction of anaesthesia was experienced in the majority of children. Recovery of children in both groups were similar / 82% of the S/M group were fully recovered 120 minutes post-operatively versus 80% in the K/M group [p&gt / 0,05]. Effective postoperative analgesia for multiple extractions was provided. For pain evaluation, children were divided into two groups, a non-responder group where all pain values over time were more than 40 and a responder group where pain values were equal to, or less than 40. Seventy two percent of children in the S/M group were responders as to fifty two percent in the K/M group [p&gt / 0,05]. No adverse respiratory, cardiovascular or other effects were recorded. This study showed that intranasal administration of sufentanil /midazolam or ketamine/midazolam, provides safe and effective sedation and analgesia in children aged 5&ndash / 7 years undergoing multiple dental extractions.

<p>This thesis covered the fast track assessment of the referred dental patient for conscious sedation in a day clinic. The assessment took in consideration patient information, medical history, anatomical observations, treatment required, phobic aspects and patient expectations.</p>

Anesthesia support personnel (ASP) provide direct support to health care providers administering anesthesia (Certified Registered Nurse Anesthetists [CRNAs] and anesthesiologists). Because these anesthesia providers are caring for a patient whom they cannot legally or ethically leave unattended, ASP are employed to bring them extra supplies or equipment, prepare equipment for the case, maintain and clean equipment, and generally function as directed by the anesthesia provider. Given the limited literature and importance of ASP in maintaining equipment essential to safe practice, it is necessary to describe the population to understand who is functioning in this role to insure that these individuals are trained and capable of complying with safety standards. There are two studies in the literature describing this population. The first study presents a descriptive survey of ASP utilization in anesthesiology residency training programs revealing varied utilization and qualifications of ASP (McMahon & Thompson, 1987). The second study is a survey of a convenience sample of the membership of the professional organization of ASP, which offers voluntary certification (American Society of Anesthesiology Technologists and Technicians). This survey reveals variation in utilization and qualification of ASP as well. The present prospective descriptive survey of CRNAs working with ASP was conducted to describe this population in terms of their educational characteristics and training, specific job functions, and work environment. It further evaluated perceptions of practicing CRNAs regarding the utilization of ASP. The results of this study were consistent with that of previous work and indicated that ASP utilization varies by hospital but has a propensity for greater utilization at larger medical centers that have a level I or II trauma designation. Formal ASP supervision is limited, which restricted the results to CRNA reports of tasks ASP performed and perceptions of CRNAs regarding ASP. ASP tasks tended to be limited to more equipment cleaning and maintenance type tasks with a smaller portion of ASP performing tasks related to direct patient care. Overall, the description of ASP in the literature remains variable and further research is needed to adequately describe this population and begin to develop a common language to understand this practice group.

Ph.D. (Zoology) / Please refer to full text to view abstract

A research University fulfillment Medicine (in report submitted to the Faculty of Medicine, of the Witwatersrand, Johannesburg, in partial of the requirements for the degree of Master of the branch of Anaesthesia / Recognising that halothane is declining as the volatile anaesthetic agent of choice for inhalational induction and that isoflurane is replacing it, particularly in North America and Europe, this study was designed to determine whether isoflurane is comparable to halothane with respect to speed of induction and complication rate when used for rapid inhalational induction (RII) of anaesthesia. / IT2018

Ivan Timothy Houghton. / Thesis (M.D.)--Chinese University of Hong Kong, 1993. / Includes bibliographical references (leaves 237-290). / Table of Contents --- p.5 / Signed Statement --- p.8 / List of Illustrations --- p.9 / List of Tables --- p.13 / Abstract --- p.16 / Publications and Presentations Resulting from the Work of the Thesis --- p.21 / Section I Introduction and Methods / Chapter Chapter1 --- Thesis Statement and Problem --- p.30 / Hypothesis and Objective of Thesis --- p.30 / Objectives --- p.30 / Review of Literature --- p.30 / Studies undertaken --- p.47 / Chapter Chapter2 --- Methods --- p.51 / Ethical Approval --- p.53 / Clinical Studies --- p.51 / Laboratory Studies --- p.53 / Equipment --- p.56 / Assays --- p.60 / Section II Intubation / Chapter Chapter3 --- Sympathoadrenal Response to Intubation --- p.65 / Chapter Chapter4 --- Suxamethonium Myalgia --- p.81 / Chapter Chapter5 --- An Antidepolarising Muscle Relaxant for Intubation --- p.106 / Section III Use of Opioids / Chapter Chapter6 --- Pethidine Pharmacokinetics --- p.126 / Chapter Chapter7 --- Ventilatory Response to Carbon Dioxide with Morphine --- p.151 / Chapter Chapter8 --- Alfentanil Supplementation --- p.166 / Chapter Chapter9 --- Response to Pethidine and Nalbuphine Analgesia --- p.184 / Section IV Use of Halothane / Chapter Chapter10 --- Determination of Minimum Alveolar Concentration of Halothane .。 --- p.203 / Annexure --- p.213 / Section V Summary and Conclusions / Chapter Chapter11 --- Summary --- p.217 / Conclusions --- p.232 / Suggestions for further research --- p.235 / "Section VI References, Author Index and Appendices" / References --- p.237 / Author Index --- p.291 / Appendices / Chapter i. --- Acknowledgements --- p.315 / Chapter ii --- Personal Work --- p.318 / Chapter iii --- Glossary of Terms --- p.320 / Chapter iv --- Ethical Committee Approval Certificates --- p.322 / Chapter v. --- Consent forms --- p.341 / Addendum / Individual Patient Data Tables / Statistical Data Tables / Table of Contents --- p.365 / Section II Intubation / Chapter Chapter 3 --- Sympathoadrenal Response to Intubation / Individual patient data table --- p.367 / Statistical data tables --- p.377 / Chapter Chapter 4 --- Suxamethonium Myalgia / Individual patient data table --- p.386 / Statistical data tables --- p.415 / Chapter Chapter 5 --- An Antidepolarising Muscle Relaxant for Intubation / Individual patient data table --- p.419 / Statistical data tables --- p.442 / Section III Use of Opioids / Chapter Chapter 6 --- Pethidine Pharmacokinetics / Individual patient data table I --- p.443 / Individual patient data table II --- p.460 / Individual patient data table III --- p.464 / Statistical data tables --- p.478 / Chapter Chapter 7 --- Ventilatory Response to Carbon Dioxide with Morphine / Indivdual patient data table --- p.483 / Statistical data tables --- p.525 / Chapter Chapter 9 --- Response to Pethidine and Nalbuphine Analgesia / Individual patient data table --- p.527 / Section IV Use of Halothane / Chapter Chapter 10 --- Determination of Minimum Alveolar Concentration of Halothane / Individual patient data table --- p.544 / Statistical data tables --- p.553 / Section V Summary and Conclusions / Chapter Chapter 11 --- Aggregated Data / Anthropometric data / Individual patient data table --- p.554 / Biochemical data / Individual patient data table --- p.573 / Cardiovascular data / Individual patient data table --- p.577 / Statistical Table --- p.596