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Yes / The aim of this chapter is to explore how social choice theory and the capability approach can help in clarifying important ethical dilemmas and issues of injustice that need to be addressed for cities to become sustainable cities. Six types of important injustices are identified covering both intra and inter-generational fairness. Some important criticisms of smart cities are considered and important safeguards and policy priorities for smart cities from the social choice and capability approach framings are identified. The main message of this chapter is that sustainability of cities is an ethical issue and not one of technology or measurement and it is all about the six types of injustices and that cities need to tackle all six of these injustices in their quest to become sustainable. Nudging and smart cities can help but these must be contextualised to priorities participation and equality. Social choice theory as formulated by Amartya Sen provides important insights to understand and deal with conflicts between different demands on freedoms of different individuals. / British Academy

No / Using an Osteobiographical approach, this contribution considers the identity of the woman found alongside the St Bees Man, one of the best-preserved archaeological bodies ever discovered. Osteological, isotopic and radiocarbon analyses, combined with the archaeological context of the burial and documented social history, provide the basis for the identification of a late 14th-century heiress whose activities were at the heart of medieval northern English geopolitics.

Yes / The integrin family of cell surface extracellular matrix binding proteins are key to several physiological processes involved in tissue development, as well as cancer proliferation and dissemination. They are therefore attractive targets for drug discovery with cancer and non-cancer applications. We have developed a new integrin antagonist chemotype incorporating a functionalised cyclobutane ring as the central scaffold in an arginine–glycine–aspartic acid mimetic structure. Here, we report the synthesis of cyclobutanecarboxylic acids and cyclobutylamines with tetrahydronaphthyridine and aminopyridine arginine mimetic sidechains and masked carboxylic acid aspartic acid mimetic sidechains of varying length. Effective αvβ3 antagonists and new aspartic acid mimetics were identified in cell-based adhesion and invasion assays. A lead compound selected based on in vitro activity (IC50 < 1 μM), stability (t1/2 > 80 minutes) and synthetic tractability was well-tolerated in vivo. These results show the promise of this synthetic approach for developing αvβ3 antagonists and provide a firm foundation to progress into advanced preclinical evaluation prior to progression towards the clinic. Additionally, they highlight the use of functionalised cyclobutanes as metabolically stable core structures and a straightforward and robust method for their synthesis. This important contribution to the medicinal chemists' toolbox paves the way for increased use of cyclobutanes in drug discovery. / This work was funded by Yorkshire Cancer Research (Award reference number B002-PhD) and Prostate Cancer UK (Pilot Grant PA10-01).

This study discusses the evolutionist approach to African history as an action plan for challenging the hegemony of English in university education and in the teaching and writing of literature in post-independence Africa. The researcher selected Zimbabwe’s university education and literary practice as the microcosm case studies whilst Africa’s university education and literary practice in general, were used as macrocosmic case studies for the study. Some two universities: the Midlands State University and the Great Zimbabwe State University and some six academic departments from the two universities were on target. The researcher used questionnaires to access data from university students and lecturers and he used interviews to gather data from university departmental Chairpersons, scholars, fiction writers and stakeholders in organizations that deal with language growth and development in Zimbabwe. Data from questionnaires was analysed on the basis of numerical scores and percentage of responses. By virtue of its not being easily quantified, data from interviews was presented through capturing what each of the thirteen key informants said and was then analysed on the basis of the hegemonic theory that is proposed in this study. The research findings were discussed using: the evolutionist approach to the history of Africa; data from document analysis; information gathered through the use of the participant and observer technique and using examples from what happened and/or is still happening in the different African countries. The study established that the approaches which have so far been used to challenge the hegemony of English in post-independence Africa are not effective. The approaches are six in total. They are the essentialist, the assimilationist, the developmentalist, the code-switch, the multilingualist and the syncretic. They are ineffective since they are used in a wrong era: That era, is the era of Neocolonialism (Americanization of the world). Therefore, the researcher has recommended the use of the evolutionist approach to African history as a strategy for challenging the hegemony in question. The approach lobbies that, for Africa to successfully challenge that hegemony, she should first of all move her history from the era of Neocolonialism as she enters the era of Nationalism. / African Languages / (D.Litt. et Phil. (African Languages))

This study compared three methods of selecting the best discriminating test items and the resultant test reliability of mastery/nonmastery classifications. These three methods were (a) the agreement approach, (b) the phi coefficient approach, and (c) the random selection approach. Test responses from 1,836 students on a 50-item physical science test were used, from which 90 distinct data sets were generated for analysis. These 90 data sets contained 10 replications of the combination of three different sample sizes (75, 150, and 300) and three different numbers of test items (15, 25, and 35). The results of this study indicated that the agreement approach was an appropriate method to be used for selecting criterion-referenced test items at the classroom level, while the phi coefficient approach was an appropriate method to be used at the district and/or state levels. The random selection method did not have similar characteristics in selecting test items and produced the lowest reliabilities, when compared with the agreement and the phi coefficient approaches.

Thesis (Ph.D. (Industrial Psychology))--North-West University, Potchefstroom Campus, 2009.

<p>This paper offers to measure efficiency of banks in Sub Saharan Africa and its determining input andout put factors on two fonts. At this purpose, we applied the first font; Data Envelopment Analysis(DEA) for assessing efficiency level. The actual and target level of inputs/outputs to foster efficiencyare shown in the results. Secondly, the banks ratio analysis measuring banks performance throughreturns volatility for each bank, asset utilization and provision for bad and doubtful debts over thestudy period are all used as tools for this analysis. Our results suggest that Sub Saharan AfricanBanks are about 98.35% efficient. We are aware that the level of efficiency could be subject to up anddown swing if environmental factors influencing banks efficiency where taken into consideration.Finally, our result (DEA) is more sensitive to loans, other liabilities, other non interest expense,securities and deposit.</p>

This paper offers to measure efficiency of banks in Sub Saharan Africa and its determining input andout put factors on two fonts. At this purpose, we applied the first font; Data Envelopment Analysis(DEA) for assessing efficiency level. The actual and target level of inputs/outputs to foster efficiencyare shown in the results. Secondly, the banks ratio analysis measuring banks performance throughreturns volatility for each bank, asset utilization and provision for bad and doubtful debts over thestudy period are all used as tools for this analysis. Our results suggest that Sub Saharan AfricanBanks are about 98.35% efficient. We are aware that the level of efficiency could be subject to up anddown swing if environmental factors influencing banks efficiency where taken into consideration.Finally, our result (DEA) is more sensitive to loans, other liabilities, other non interest expense,securities and deposit.