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The effects of habitat features on the distribution of ringed seals (Phoca hispada) in the fast ice of Barrow Strait were examined between March and June 1984 to 1986. Breathing hole density in thirty-two, 2-4 km$ sp2$ study plots provided an index of seal abundance. Densities of seal holes were determined using a combination of trained dogs to locate the subnivean breathing holes and removal sampling. / Birth lairs were not seen before 4 April, but the incidence of these structures increased as the season progressed. Structures maintained by male seals were evident in late March, but were not found after mid-May. In 1984, densities of seal holes were correlated with ice thickness. In 1985, no relationship was detected between seal hole density and habitat. In 1986, the highest densities of subnivean structures including birth lairs, were associated with deep snow conditions located in areas of late consolidating ice. No relationship was identified between the density of male structures and any habitat variables. / The mean reproductive rate for females $>$7 years old was 0.64. Between March and June for adult males lost 204 g per day with 72% of this weight being lost from blubber. Pregnant females lost 467 g per day with 68% of the loss occurring from the blubber. In adult seals no differences in body condition were detected between sexes or between years, but juveniles collected in 1986 were in significantly better condition than juveniles collected in 1984 and 1985.

This thesis is concerned with approaches to identity in archaeology, specifically the later prehistory of East Yorkshire, during the first millennium B. C. The region is characterised by a middle-late Iron Age square barrow burial rite, which has been interpreted as the product of the 'Arras' culture. It tackles the problem that identity has traditionally been understood as a social given (as part of an evolutionary process or an innate condition of a social group) that can be read from material remains. It argues that such models fail to make a critical enquiry into how identity is reproduced, with damaging social and political implications. In contrast, the thesis argues that identity is the project through which people come to know themselves as social beings, through the webs of their relations with others and the material world. Identity always takes work, and is constituted through that work. Archaeology therefore explores how identities were reproduced and mobilised over time, through an analysis of material fragments which are both the product and conditions of identity practice The thesis explores the contrasting character of practices of inhabitation from the later Bronze Age - late Iron Age (c. 8 th -I' century B. C. /A. D. ). It interprets the emergence and disappearance of the burial rite in terms of the political projects and discourses of identity which were reproduced through the strategic manipulation of the dead. More broadly, it argues that archaeology is both an analytical and interpretative endeavour. It presents the theoretical grounds of its approach, a methodology for exploring identity, and the results of its analysis (including a report on original fieldwork undertaken at Wharram Grange Crossroads, East Yorkshire). It also argues that the way in which this interpretative process is returned to the reader is constitutive of the meaning that they make, and it develops ways in which this can be made explicit in the writing of a thesis.

Thesis (M. Div.)--Gordon-Conwell Theological Seminary, South Hamilton, Mass., 1998. / Abstract and vita. Includes bibliographical references (leaves 84-92).

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This study explores the use of the doctrine of the offices of Christ (prophet, priest, and king) in the literature of the English separatists Henry Barrow (c.1550-1593) and Henry Ainsworth (1569-1622). No study to date explores the English separatists’ use of the doctrine in ecclesiological debates. During the period 1580 to 1620 the doctrine was more commonly referenced when discussing soteriology. Barrow and Ainsworth provide some of the clearest expressions of the doctrine of the offices of Christ in separatist works and their steadfastness in those beliefs in light of opposition make them good candidates for this research. This study sets out to answer the question: what was the significance of participation by the elect in the offices of Christ as used in Barrow and Ainsworth’s writings? This research focuses on the theology of Barrow and Ainsworth and does not consider the social or experiential aspects of their professed beliefs. This study provides a detailed analysis of the writings of Barrow and Ainsworth particularly noting their use of the offices of Christ in discussions of the visible church. It then examines the relationship of Barrow and Ainsworth’s Christology and ecclesiology, expressed through the offices of Christ, in their understanding of the visible church. Finally, this research compares their usage with works published in England from 1580 to 1620, considering whether their usage was distinct. Its findings challenge the traditional historiographical suggestions that purity, polity, discipline, and covenant were the central themes of Barrow and Ainsworth’s ecclesiology. This research suggests that, for Barrow and Ainsworth, the visible church was the visible expression of Christ on earth and the continuation of his earthly ministry begun at the incarnation. They believed that the visible church was the result of union with Christ, not the means of it. Through union with Christ, all the elect participated in Christ’s offices. Barrow and Ainsworth’s understanding of the visible church incorporated their understanding of Christ’s continuing work expressed in his offices of prophecy, priesthood, and kingship. Christ was immediately present in his visible church, working in the elect and through the elect as prophets, priests, and kings. The visible elect, when gathered, became the body of Christ on earth and as his body they continued the work of prophecy, priesthood, and kingship that he had begun.

A chronostratigraphic subdivision of the Upper Jurassic synrift sediments in the eastern Barrow Sub-basin was developed from the integration of core logging, petrography, well log sequence analyses and seismic stratigraphy. From this basis, the Callovian to base Cretaceous sediments may be subdivided into five depositional sequences. The development of the sequence boundaries, in most part, is closely related to periods of major changes in basin configuration associated with the sequential breakup of eastern Gondwanaland. Initiation of the Upper Jurassic rift complex occurred during late Callovian early Oxfordian associated with the development of a northeast-southwest trending spreading centre on the Argo Abyssal Plain. The spreading centre propagated southwards during the Late Jurassic. This resulted in active rifting in the Barrow Sub-basin and ultimately led to the separation of the Indian and Australian plates during Valanginian time.Upper Jurassic synrift sediments in the eastern Barrow Sub-basin consist of detached basin floor fan complexes, channelised and canyon fed fan systems, slump deposits, prograding outer shelfal to slope deposits and deep marine claystones. Post-depositional uplift of the eastern shelfal areas during the Late Jurassic resulted in erosion of the transgressive and highstand fluvial-deltaic to shelfal deposits. These periods of uplift and erosion provided much of the sediment redeposited in the basinal areas during the lowstand periods. Seven sandstone facies were recognised in the Upper Jurassic sedimentary section based on core control. Each sandstone has unique reservoir characteristics which can be related to the depositional setting. / The abundance of glauconite and belemnites combined with ichnology and biostratigraphic assemblages associated with marine environments, indicate that deposition of all the sandstone facies occurred within an outer shelfal - deep marine environment. Reservoir quality was best developed in the dominantly medium grained, moderate - well sorted sandstones, (facies 7), which were deposited as detached, basin floor submarine fan sands or interbedded turbidites. In contrast, reservoir quality was relatively poorly developed in the remaining facies which were deposited as slope fans, slumps, or distal turbidite deposits.The abundance of quartz and presence of banded iron, jasper, and potassic feldspar grains support the provenance for the basinal sandstone facies being the Precambrian alkyl granites and banded iron formation of.the Pilbara Shield and Hammersley Ranges. These Precambrian igneous rocks and metasediments mark the eastern boundary of the Barrow Sub-basin study area. To predict the distribution of sedimentary facies in the Upper Jurassic synrift sediments of the eastern Barrow Sub-basin, the interplay between the major controlling depositional processes, namely tectonics, sediment supply and eustasy must be understood. Subdivision of the synrift sedimentary section on the basis of lithostratigraphy can be misleading and does not adequately resolve the facies relationships observed in the well intersection. The results of this research form the basis for a regional sequence analysis and seismic stratigraphic study.

A sea ice model developed by W. D. Hibler (1979) was applied to the Lancaster Sound/Barrow Strait channel in an effort to simulate the observed ice environment. The simulation covered a ten month period, from October 1985 until August 1986. The impact of atmospheric and oceanographic forcing on the development of characteristic ice features that develop seasonally within the channel was examined. The importance of the ice interaction component of the model when simulating a restricted channel ice environment was also examined. The model was able to simulate regional scale processes and conditions within the channel. Small scale localised processes and conditions which control the spatial variability and complexity of the ice regime were not accurately reproduced. Simulation results provided insights into the effect and importance of both the model and geophysical variables examined. The study highlighted concerns that need be addressed in future modelling work in the Lancaster Sound/Barrow Strait channel.

abstract: Glioblastoma (GBM) is the most common primary brain tumor with an incidence of approximately 11,000 Americans. Despite decades of research, average survival for GBM patients is a modest 15 months. Increasing the extent of GBM resection increases patient survival. However, extending neurosurgical margins also threatens the removal of eloquent brain. For this reason, the infiltrative nature of GBM is an obstacle to its complete resection. We hypothesize that targeting genes and proteins that regulate GBM motility, and developing techniques that safely enhance extent of surgical resection, will improve GBM patient survival by decreasing infiltration into eloquent brain regions and enhancing tumor cytoreduction during surgery. Chapter 2 of this dissertation describes a gene and protein we identified; aquaporin-1 (aqp1) that enhances infiltration of GBM. In chapter 3, we describe a method for enhancing the diagnostic yield of GBM patient biopsies which will assist in identifying future molecular targets for GBM therapies. In chapter 4 we develop an intraoperative optical imaging technique that will assist identifying GBM and its infiltrative margins during surgical resection. The topic of this dissertation aims to target glioblastoma infiltration from molecular and cellular biology and neurosurgical disciplines. In the introduction we; 1. Provide a background of GBM and current therapies. 2. Discuss a protein we found that decreases GBM survival. 3. Describe an imaging modality we utilized for improving the quality of accrued patient GBM samples. 4. We provide an overview of intraoperative contrast agents available for neurosurgical resection of GBM, and discuss a new agent we studied for intraoperative visualization of GBM. / Dissertation/Thesis / Ph.D. Neuroscience 2014

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