Mapping studies of the centromeric region of the human Y chromosome Construction of a map of a human centromeric region is very important in order to understand the organisation of this essential part of the chromosome. A YAC contig map has been assembled of the pericentric 10 Mb of the human Y chromosome, giving coverage of Yp from the large X-Y homologous region through to the alphoid satellite of the centromere, and from the alphoid DNA to the proximal unique sequences on Yq. The Yp map has one remaining gap between TSPY1 and the AMELY region, while two gaps separate the satellite region on Yq from the other two contigs. After constructing the map, the known genes were localised to the region. One Yq gene, DFFRY, was discounted as a potential anti-Turner syndrome gene by analysis of rearranged Y chromosomes. Detection of a block of duplicated sequence on Yp led to the confirmation of the existence of an inversion polymorphism, which was then found to be correlated with a major subclass of sex-reversed individuals, who have X-Y chromosomal breakpoints within the inverted region. These results not only give a far more extensive and detailed map of this region than before, but also show that understanding the organisation of the region has important consequences for a number of genetic disorders.

Thesis (M.A.)--University of Hawaii at Manoa, 2004. / Includes bibliographical references (leaves 84-91). / 91 leaves, bound 29 cm

Thesis (Ph. D.)--University of Missouri-Columbia, 2007. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on March 4, 2008) Vita. Includes bibliographical references.

Thesis (M.S. - Hydrology and Water Resources)--University of Arizona. / Includes bibliography.

Thesis (Ph.D.)--Tufts University, 2003. / Adviser: Linda Bamber. Submitted to the Dept. of English. Includes bibliographical references (leaves 246-251). Access restricted to members of the Tufts University community. Also available via the World Wide Web;

Thesis (M.A.)--University of Toronto, 2004. / Adviser: Barrie Bennett.

Thesis (M.A.)--University of Notre Dame, 2008. / Thesis directed by Roy McVeigh for the Department of Sociology. "March 2008." Includes bibliographical references (leaves 32-37).

Thesis (Ph. D.)--Antioch University New England, 2008. / Title from PDF t.p. (viewed Oct. 24, 2008). "A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy Environmental Studies at Antioch University New England (2008)."--The title page. Advisor: Thomas Webler, Ph. D. Includes bibliographical references (p. 156-159).

Thesis (Ph. D.)--University of Technology, Sydney, 2008. / Bibliography: leaves 321-331. Also issued online.

Thesis (Ph.D.)--Australian National University, 2003.