In wireless sensor networks, communications are usually destroyed by signal attenuation, multipath fading and different kinds of interferences like WLAN and microwave oven interference. In order to build a stable wireless communication system, reactions like retransmission mechanisms are necessary. Since the way we must react to interference is different from the way we react to multipathfading and attenuation, the retransmission mechanism should be adjusted in different ways under those different cicumstances. Under this condition, channel diagnostics for discriminating the causes that corrupt the packets between multipath fading and attenuation (MFA) and WLAN interference are imperative. This paper presents a frame bit error rate (F-BER) regulated algorithm based on a joint RSSI-LQI classifier that may correctly diagnose the channel status. This discriminator is implemented on MicaZ sensor devices equipped with CC2420 transceivers. This discriminator is able to improve the accuracy to 91%. Although we need to wait for 2 or 3 necessary packets to make a decision, higher stability and reliability are presented when operating this discriminator.

Abstract The main objective of this thesis project is to implement a wireless vital signs monitoring system for measuring the ECG of a patient in the home environment. The research focuses on two specific research objectives: 1) the development of a distributed healthcare system for vital signs monitoring using wireless sensor network devices and 2) a practical test and performance evaluation for the reliability for such low-rate wireless technology in ubiquitous health monitoring applications. The first section of the thesis describes the design and implementation of a ubiquitous healthcare system constructed from tiny components for the home healthcare of elderly persons. The system comprises a smart shirt with ECG electrodes and acceleration sensors, a wireless sensor network node, a base station and a server computer for the continuous monitoring of ECG signals. ECG data is a commonly used vital sign in clinical and trauma care. The ECG data is displayed on a graphical user interface (GUI) by transferring it to a PDA or a terminal PC. The smart shirt is a wearable T-shirt designed to collect ECG and acceleration signals from the human body in the course of daily life. In the second section, a performance evaluation of the reliability of IEEE 802.15.4 low-rate wireless ubiquitous health monitoring is presented. Three scenarios of performance studies are applied through practical tests: 1) the effects of the distance between sensor nodes and base-station, 2) the deployment of the number of sensor nodes in a network and 3) data transmission using different time intervals. These factors were measured to analyse the reliability of the developed technology in low-rate wireless ubiquitous health monitoring applications. The results showed how the relationship between the bit-error-rate (BER) and signal-to-noise ratio (SNR) was affected when varying the distance between sensor node and base-station, through the deployment of the number of sensor nodes in a network and through data transmission using different time intervals.

From gametogenesis until death an organism’s genome is under constant bombardment from endogenous and exogenous sources of DNA damage. To maintain genomic integrity amid this damage, cells have evolved responses which allow them to either preserve viability for recovery or initiate self-destructive pathways depending on the severity of DNA damage. One protein involved in initiating and carrying out these responses is the protein kinase ataxia telangiectasia and Rad3-related (ATR). ATR is known primarily for its regulatory role in initiating the checkpoint-signaling cascade following DNA damage and replicative stress. These signaling events lead to cell cycle arrest, DNA repair, or apoptosis when damage is too extreme. In addition to these kinase-dependent roles, ATR also is capable of directly blocking the intrinsic apoptotic pathway through structural sequestration of the proapoptotic protein tBid. The sum of these regulatory events is a delicate balancing act resulting in either cell death or cell survival depending on the severity of the damage and the differentiation state of the cell in question. In the following studies, we sought to investigate the complex interplay of ATR’s kinase and structural roles in determining cellular fate. First, we investigated the structural role of prolyl isomerization of ATR across development by using mouse models of two isomerically locked forms of ATR which were previously shown to lock cytoplasmic ATR into a single isomer. Studies showed that ATR which is locked in ATR-L (trans-ATR, hATR-P429A/mATR-P432A) is embryonically lethal and that heterozygotes tend to have neurological and other developmental abnormalities. This contrasts with ATR-H (cis-ATR, hATR-S428A/mATR-S431A), which is viable, but naturally prone to cancer development. Next, we used various in vitro stroke-like conditions to test if ATR inhibition could serve as a therapeutic target for stroke. We found that ATR inhibition is protective in non-dividing neuron-like cells; whereas, it potentiates death in cycling glial and immune-like cycling cells. Thus, ATR inhibition could likely be a target for both neuron sparing and immunosuppressive anti-stroke therapeutic strategies. Taken together, these studies provide insightful information into the structural and pathological roles of ATR in development and disease.

The master thesis discusses physical causes of light polarization and problems brought by nascence of Polarization Mode Dispersion (PMD). These problems occur especially by high speed systems on optical cable traces. The thesis deals with actuation of transmitted signal by influence of Inter Symbol Interference and it also deals with methods for its measuring and compensation. As a results of measurements are in text presented data provided by EXFO Electro-Optical Engineering Inc. Company. Significant part of the thesis focuses on optical link Bit Error Rate (BER) which is connected with Signal to Noise Ratio (SNR) and signal quality (Q-factor). Further on it is possible to find in text about so called eye diagram which is display mode that shows influence of communication channel on shape of the transmitted signal. To this diagram is related another one called constellation diagram which describes modulation mode and makes it possible to map dispersion of signal points around their nominal values. In connection with so called trajectory it makes vector diagram. Practical part includes depiction of these diagrams in MATLAB development environment.

This thesis concisely describes essential type of modulation technique for transmission of binary signal. In introductory part there are summarized advantages and disadvantages for each described modulation technique. There are described proceeding of modulation and demodulation too. Next part is specialized mainly to determination of incorrect receiving probability. For each modulation technique are calculated theoretical values of bit error rate and compiled graph. In practical part there are described possibilities of Matlab platform for measurement of bit error rate. In implement Simulink there is built model of communication channel with additional AWGN channel. Graphs are constructed from simulation data by the help of model’s control script. On selected modulation technique are inspected various elements which are reacted with graph. In finale part there are compared theoretical and measured values and summarized analysis.

This Master thesis is focused on detailed description of the DVB-T2 system. This work deals with the description of the particular parts of models and with typical RF transmission channels for fixed and mobile reception. In order to simulate the impact of the fading transmission channels on the transmitted signal there was developed an appropriate application in MATLAB. The graphic user interface of this application allows set the transmission parameters of DVB-T2 and the parameters of the transmission channels. Results of simulations with various settings are evaluated and compared with the results, obtained from the DVB-T measurements.

The purpose of this paper is to study the possibilities of the OFDM system adaptive modulation. The study presents mechanism for acquiring the necessary data of every frequency subchannel using pilot signals and application of these data for system adjustment. The paper introduces the water-filling principle for subchannel power allocation on the basis of their SNR and adaptive modulation mechanisms for variety of OFDM usage. These mechanisms are implemented into a MATLAB model. The code is then transformed into graphical representation and using USRP2, the signal is transmitted by real world channel.

This thesis is focusing on the second satellite digital TV standard, DVB-S2. It deals with the principle of the digital TV and the first standard DVB-S. It also describes the very beginning and characteristics of the DVB-S2, new technologies in use, architecture and the individual topics are then explained more in detail. The thesis also contains the program of transmission simulation of DVB-S2 in MATLAB. In the laboratory of television technology UREL, two standards were measured and compared with the values obtained from the program. The functionality of the program and the benefits of DVB-S2 were verified afterwards.

This Master thesis deals with description, analysis and simulation of standards of digital video broadcasting DVB-C and DVB-C2. There is described mainly the transmission system, channel coding, type of modulation and OFDM symbols generation. Furthermore, channel models, used for the exploring of their performances are described too. There was created an application with a graphical interface in MATLAB, which simulates transmission in DVB-C2. Based on simulations there are compared influences of each settings on bit error rate of data transmission for both standards. Finally, obtained simulation results are compared with theoretical values.

Tato disertační práce se zabývá analýzou, simulací a měřením zpracování a přenosu signálů digitální televize pro příjem mobilního TV vysílání ve standardech DVB-H a DVB-SH. Tyto standardy vycházejí z předpokladu, že příjem signálu je charakterizován modely přenosových kanálů s vícecestným šířením. Tyto, tzv. únikové kanály, jsou charakterizovány hlavně zpožděním a ziskem jednotlivých cest. V závislosti na dalších parametrech (rychlost přijímače, Dopplerovské spektrum), je možné rozdělit únikové kanály do třech hlavních skupin: mobilní, přenosné a fixní. Dá se předpokládat, že v různých modelech kanálů bude přenášený signál různě ovlivněn. Proto je potřebné najít optimální parametry systémů (DVB-H/SH) pro kvalitní příjem vysílaných služeb mobilní televize, což je hlavním cílem této disertační práci. Pro tento účel byly vytvořeny dvě vhodné aplikace (jedna pro DVB-H a jedna pro DVB-SH) s GUI v prostředí MATLAB, které umožňují simulovat a analyzovat míru zkreslení signálu v případě mobilních, přenosných a fixních scénářů přenosu. Navíc, tyto aplikace obsahují i druhý samostatný simulátor pro nastavení a modifikaci parametrů jednotlivých přenosových cest. Díky tomu je možné zhodnotit vliv parametrů celého systému a kanálových modelů na dosaženou chybovost (BER a MER) a kvalitu přenosu. Ve všech přenosových scénářích (v závislosti na poměru C/N) byly získané, vyhodnocené a diskutované zkreslení signálů. Navíc, u standardu DVB-H, všechny získané výsledky ze simulací byly ověřeny měřením. Rozdíly mezi dosaženými výsledky (simulace a měření) byly rovněž podrobeny diskuzi. Tuto disertační práci je možné rozdělit do čtyř hlavních částí. První část disertační práce se zabývá rešerší současného vývoje v oblasti digitálního televizního vysílání na mobilní terminály ve standardech DVB-H/SH. Na konci této části jsou jasně popsány cíle této disertační práce. Druhá část práce je zaměřená na stručný popis blokového diagramu vysílačů v obou standardech DVB-H/SH. Dále jsou stručně popsány modely přenosových kanálů, které se používají pro modelování přenosu signálu. Stručný popis vytvořených aplikací, i s vývojovým diagramem, které jsou vhodné pro simulaci a analýzu přenosu v DVB-H/SH, jsou popsány v třetí části práce. Čtvrtá a nejdelší část této disertační práce se zabývá vyhodnocením získaných výsledků ze simulací a měření.