Purpose: The present study aimed to evaluate the impact of bruxism on dental implant failure rates andmarginal bone loss (MBL), based on a systematic review of the literature. Materials and methods: An electronic search without time restrictions was undertaken (last updated in September2021) in three databases, plus handsearching. Only studies that provided enough informationon the criteria used for the diagnosis of at least ‘probable bruxism’ (self-report + clinicalexamination) were considered for inclusion. Meta-analyses were performed besides meta-regressions, in order to verify how the odds ratio (OR) was associated with follow-up time. Results: The review included 23 publications. Altogether, there were 1,991 and 9,438 implants placedin bruxers and non-bruxers, respectively. Pairwise meta-analysis including only the studiesthat provided enough information on the criteria used for the diagnosis of at least ‘probablebruxism’ resulted in significant failure rate difference between the groups (OR 1.987, p =0.015). There was an estimated increase of 0.010 in OR for every additional month of follow-up (p = 0.209). None of the included studies reported results on MBL separated betweenbruxers and non-bruxers. Conclusion: Implants placed in bruxers present a significant higher risk of failure than in non-bruxers.Studies comparing MBL between the groups are still lacking. / Syfte Den aktuella studien syftade till att utvärdera effekten av bruxism på dentala implantats misslyckandefrekvens och marginell benförlust (MBL), baserat på en systematisk översikt av litteraturen. Material och metod: En elektronisk sökning utan tidsbegränsningar gjordes (senast uppdaterad i september 2021) i tre databaser, plus handsökning. Endast studier som gav tillräckligt med information om de kriterier som användes för diagnos av åtminstone ’trolig bruxism’ (självrapportering + klinisk undersökning) övervägdes för inkludering. Metaanalyser utfördes förutom metaregressioner, för att verifiera hur oddskvoten (OR) var associerad med uppföljningstid. Resultat: Översikten omfattade 23 publikationer. Sammanlagt fanns det 1 991 och 9 438 implantat placerade i bruxare respektive icke-bruxare. Parvis metaanalys som endast inkluderade studierna som gav tillräckligt med information om kriterierna som användes för diagnosen av åtminstone ’probable bruxism’ resulterade i signifikant skillnad i felfrekvens mellan grupperna (OR 1,987, p = 0,015). Det var en uppskattad ökning med 0,010 i OR för varje ytterligare månad av uppföljning (p = 0,209). Ingen av de inkluderade studierna rapporterade resultat på MBL separerade av bruxare och icke-bruxare. Slutsats: Implantat placerade i bruxare innebär en signifikant högre risk för misslyckande än hos icke-bruxare. Studier som jämför MBL mellan grupperna saknas fortfarande.

Indiana University-Purdue University Indianapolis (IUPUI) / The objectives: 1. To compare the flexural strength, flexural modulus, and fracture toughness of specimens fabricated from recently marketed translucent full-contour zirconia, traditional zirconia, and lithium disilicate glass ceramic. 2. To compare the load-to-failure of crowns fabricated from recently marketed translucent full-contour zirconia, traditional zirconia, and lithium disilicate glass ceramic at their recommended tooth-reduction thickness. Methodology: Four groups of translucent zirconia (BruxZir, KDZ Bruxer, CAP FZ, Suntech zirconia), one group of traditional zirconia (CAP QZ) and IPS e.maxCAD) were tested. Twelve bars of each material were made and tested for flexural strength, and fracture toughness. Fracture patterns were imaged under SEM. Forty-eight crowns (8 from each group) were fabricated with CAD/CAM technique following manufacturers’ recommendations for the amount of tooth reduction. All the crowns were cemented to prepared epoxy resin dies with RelyX Unicem and tested for static load to failure in a universal machine. Result: In bar-shape samples, CAP QZ (traditional zirconia) showed the highest flexural strength (788.12 MPa), fracture toughness (6.85 MPa.m1/2), and fracture resistance (2489.8 N). All translucent zirconia groups show lower mechanical properties than QZ. However, there were no differences between translucent and traditional zirconia in the fracture resistance of the crown-shape samples. There was no significant difference in fracture resistance between IPS e.max crowns at recommended thickness and other zirconia crowns at recommended thickness. Conclusion: With less reduction of tooth structure, a high inherent strength and chip resistance make full-zirconia crowns a good alternative to porcelain-fused-to-metal crowns and all other ceramic crowns.