From 2012 - 2015 a foundation for future research in Goodwin Hall was designed, tested,developed, and implemented through an instrumentation project supported by the College of Engineering at Virginia Polytechnic Institute and State University. This required the design and implementation of a distributed, networked, and synchronized data acquisition system along with supporting hardware and software capable of measuring 227 accelerometers placed in 129 locations throughout the building. This system will provide a platform for research into a variety of topics, including structural health monitoring, building dynamics, human motion, and energy harvesting. Additionally, the system will be incorporated into the education curriculum by providing real-world data and hardware for students to interact with. This thesis covers the contributions of the author to the project. / Master of Science