<div>Due to reduced pain, shortened hospital stay and recovery, minimally invasive surgery (MIS) is becoming more and more popular in healthcare systems. MIS requires some devices for the motion and force transformation from outside to the inside of the body of a patient, and the strangled cables play a significant role in developing the instrumentations to serve for such purposes. However, current design and selection of a strangled cable is mostly intuitive that depend greatly on designers’ experiences and availability of experimental data, which leads to non-optimized designs and longer design cycles. In this thesis, both of analytical modelling and numerical simulation are proposed to build the relation of applied torque and deflection of part, so that a strangled cable with a given configuration can be characterized in term of its load-deflection relation. The defined relation has its great significance and application potential in the design optimization and precise controls of medical devices for MISs.Besides the various patterns of strangled cables, a Helical hollow strand (HHS®) tube is a special type of strangled cables with single- or multiple- layer configurations., In each layer, each of the helical wires touches its two neighboring helical wires, and it has a coreless hollow at the center. Its primary application is to carry a torsional load in a twisting mode. As an extreme, there is a possibility that all helical wires touch each other, and this forms a statically indeterminate contact obstacle in design analysis. Numerical simulation would predict that contacts occur simultaneously at all possible contacting points under the circumference that the strand is fixed at one end against rotation. In addition, the friction at contacts will affect the torsional deformation; therefore, these contacts must be taken into consideration in the development of analytical and numerical simulation models.This thesis reports the results of the investigation on the characteristics of Helical hollow strand tube (HHS®), more specifically, the relation of torsional deflection and the applied torque over a tube in the clockwise (CW) direction. The numerical simulation approach to predict the torsional deflection of HHS with various design parameters and configurations is emphasized. </div><div><br></div>