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Histopathological evaluation of the effects of calcium hydroxide in inducing apexification of nonvital monkey teethTasch, Gary Emerson. January 1971 (has links)
Thesis (M.S.)--University of Michigan, Ann Arbor, 1971. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 106-110).
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A clinical and radiographic evaluation of the effect of calcium hydroxide in direct pulpal capping of exposed pulps in primary teethWeine, David M. January 1962 (has links)
Thesis (M.S.)--University of Michigan, Ann Arbor, 1962. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 42-45).
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Evaluation of a new pulp capping agent: a clinical investigationNirschl, Ronald Francis January 1979 (has links)
Indiana University-Purdue University Indianapolis (IUPUI) / This study compared clinical results of two calcium hydroxide bases
used in indirect pulp therapy on human teeth.
Thirty-four teeth with deep carious lesions were treated with indirect
pulp therapy. Eighteen teeth were treated with commercially available
Improved Dycal and 16 teeth were treated with an experimental calcium
hydroxide formula.
Evaluation was made at intervals of three and six months. After
three months, periapical and bitewing radiographs were made and the teeth
were examined clinically for signs of pulpal degeneration. At the six-month
evaluation, in addition to the radiographic and clinical examinations,
cavities were re-entered and the unsound residual dentin was removed to
ascertain the presence of a so1id dentinal base. Removal of all unsound
residual dentin without an exposure of the pulp, as well as the clinical
and radiographic examinations, were used to determine clinically successful
treatment.
In the experimental group 15 teeth were successfully treated; a
success rate of 94.4 percent. Seventeen teeth in the control group
demonstrated successful indirect pulp therapy; a success rate of 93.75 percent.
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The effect of formocresol and calcium hydroxide on the dental pulps of rhesus monkeysSpedding, Robert H., 1931- January 1963 (has links)
Indiana University-Purdue University Indianapolis (IUPUI)
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Treatment of infected dental pulps of monkeys with vancomycin and calcium hydroxideGardner, Donald E. January 1969 (has links)
Indiana University-Purdue University Indianapolis (IUPUI) / This study was undertaken to investigate histologically the
effect of a combination of a potent antibiotic and calcium hydroxide
when used as a medication in direct pulp therapy.
The pulps of 74 teeth in one Macaca Speciosa monkey and
two Macaca Nemestrina monkeys were exposed and left open to the
oral environment for 48 hours to insure contamination. These
pulps received direct treatment with one of four experimental
medications: 1) starch and water; 2) vancomycin, starch and
water; 3) calcium hydroxide, methyl cellulose and water; and
4) vancomycin, calcium hydroxide, methyl cellulose and water.
In 30 days the teeth were removed from two animals and at 90
days from the other for histologic evaluation.
A satisfactory response was observed in all the teeth
treated with vancomycin, calcium hydroxide, methyl cellulose and
water; in 94.4 per cent of the teeth treated with calcium hydroxide, methyl cellulose and water; in 33.3 per cent of those treated with vancomycin and starch; and in 11.2 per cent of those receiving starch and water. Complete bridging was seen
in all teeth treated with vancomycin, calcium hydroxide, methyl
cellulose and water. This was confirmed by the use of Procion
brilliant red H-8BS dye and the study of serial sections.
Under the conditions of this investigation, vancomycin in
combination with calcium hydroxide and methyl cellulose was
effective in controlling infection and promoting reparative
dentin formation in monkeys.
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Associação de hidrocloreto de polihexametileno guanidina e hidróxido de cálcio para uso como medicação intracanalPaulus, Marília January 2017 (has links)
Objetivo: O objetivo do presente estudo foi desenvolver uma medicação intracanal contendo hidrocloreto de polihexametileno guanidina (PHMG) e hidróxido de cálcio Ca(OH)2, avaliando as suas propriedades e eficácia antimicrobiana. Métodos: O material foi formulado a partir da associação de 2% de PHMG ao pó de hidróxido de cálcio associado ao veículo propilenoglicol. O material foi avaliado pelos testes de análise antimicrobiana, escoamento, espessura de película, análise de pH e liberação de cálcio. Resultados: Os resultados foram analisados através do teste ANOVA de uma via, ANOVA de duas vias e teste tukey, com nível de significância de 5%. A atividade antimicrobiana com a associação de hidrocloreto de polihexametileno guanidina (PHMG) mostrou-se eficaz para Enterococcus faecalis. No teste de escoamento, o hidróxido de cálcio associado com o propilenoglicol mostrou um escoamento maior do que quando associado com o hidrocloreto de polihexametileno guanidina (PHMG) (p˂ 0,05). No teste de espessura de película os grupos não apresentaram diferença. Na análise de pH, os grupos variaram a alcalinidade nos tempos avaliados, durante o período de 28 dias (pH entre 7,5 – 11,5). Na liberação de cálcio, o uso do antimicrobiano hidrocloreto de polihexametileno guanidina (PHMG) não interferiu na liberação de cálcio do material. Conclusão: A adição de (PHMG) ao pó de hidróxido cálcio e ao veículo propilenoglicol não interferiu na liberação de cálcio, além de possuir efeito antimicrobiano, manteve o pH alcalino, não alterando a espessura de película, entretanto apresentou um menor escoamento do material. / Objective: The objective of the present study was to develop an intracanal medication containing polyhexamethylene guanidine hydrochloride (PHMG) and calcium hydroxide Ca (OH)2, evaluating its properties and antimicrobial efficacy. Methods: The material was formulated from the association of 2% PHMG with the calcium hydroxide powder associated with the propylene glycol vehicle. The material was evaluated by antimicrobial analysis, flow, film thickness, pH analysis and calcium release. Results: The results were analyzed through the one-way ANOVA, two-way ANOVA and tukey test, with a significance level of 5%. The antimicrobial activity with the combination of polyhexamethylene guanidine hydrochloride (PHMG) was shown to be effective for Enterococcus faecalis. In the flow test, the calcium hydroxide associated with propylene glycol showed a greater flow than when associated with polyhexamethylene guanidine hydrochloride (PHMG) (p<0.05). In the film thickness test, the groups showed no difference. In the pH analysis, the groups varied the alkalinity at the evaluated times, during the period of 28 days (pH between 7.5 - 11.5). In the release of calcium, the use of the antimicrobial polyhexamethylene guanidine hydrochloride (PHMG) did not interfere with the release of calcium from the material. Conclusion: The addition of (PHMG) to the calcium hydroxide powder and to the propylene glycol vehicle did not interfere with the release of calcium, besides having an antimicrobial effect, it maintained the alkaline pH, without altering the film thickness, however presented a lower material flow.
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Effect of Dycal on bacteria in deep carious lesionsLeung, Ralph L. January 1978 (has links)
Thesis (M.S.)--University of Michigan, Ann Arbor, 1978. / Typescript (photocopy). eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 46-48).
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Applications of theoretical chemistry : effective Hamiltonian studies of CaOH and implicit solvent simulations of poly(ethylene oxide) /Taylor, Caroline Margaret. January 2003 (has links)
Thesis (Ph. D.)--University of Chicago, Dept. of Chemistry, Mar. 2003. / Includes bibliographical references (p. 113-119). Also available on the Internet.
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Associação de hidrocloreto de polihexametileno guanidina e hidróxido de cálcio para uso como medicação intracanalPaulus, Marília January 2017 (has links)
Objetivo: O objetivo do presente estudo foi desenvolver uma medicação intracanal contendo hidrocloreto de polihexametileno guanidina (PHMG) e hidróxido de cálcio Ca(OH)2, avaliando as suas propriedades e eficácia antimicrobiana. Métodos: O material foi formulado a partir da associação de 2% de PHMG ao pó de hidróxido de cálcio associado ao veículo propilenoglicol. O material foi avaliado pelos testes de análise antimicrobiana, escoamento, espessura de película, análise de pH e liberação de cálcio. Resultados: Os resultados foram analisados através do teste ANOVA de uma via, ANOVA de duas vias e teste tukey, com nível de significância de 5%. A atividade antimicrobiana com a associação de hidrocloreto de polihexametileno guanidina (PHMG) mostrou-se eficaz para Enterococcus faecalis. No teste de escoamento, o hidróxido de cálcio associado com o propilenoglicol mostrou um escoamento maior do que quando associado com o hidrocloreto de polihexametileno guanidina (PHMG) (p˂ 0,05). No teste de espessura de película os grupos não apresentaram diferença. Na análise de pH, os grupos variaram a alcalinidade nos tempos avaliados, durante o período de 28 dias (pH entre 7,5 – 11,5). Na liberação de cálcio, o uso do antimicrobiano hidrocloreto de polihexametileno guanidina (PHMG) não interferiu na liberação de cálcio do material. Conclusão: A adição de (PHMG) ao pó de hidróxido cálcio e ao veículo propilenoglicol não interferiu na liberação de cálcio, além de possuir efeito antimicrobiano, manteve o pH alcalino, não alterando a espessura de película, entretanto apresentou um menor escoamento do material. / Objective: The objective of the present study was to develop an intracanal medication containing polyhexamethylene guanidine hydrochloride (PHMG) and calcium hydroxide Ca (OH)2, evaluating its properties and antimicrobial efficacy. Methods: The material was formulated from the association of 2% PHMG with the calcium hydroxide powder associated with the propylene glycol vehicle. The material was evaluated by antimicrobial analysis, flow, film thickness, pH analysis and calcium release. Results: The results were analyzed through the one-way ANOVA, two-way ANOVA and tukey test, with a significance level of 5%. The antimicrobial activity with the combination of polyhexamethylene guanidine hydrochloride (PHMG) was shown to be effective for Enterococcus faecalis. In the flow test, the calcium hydroxide associated with propylene glycol showed a greater flow than when associated with polyhexamethylene guanidine hydrochloride (PHMG) (p<0.05). In the film thickness test, the groups showed no difference. In the pH analysis, the groups varied the alkalinity at the evaluated times, during the period of 28 days (pH between 7.5 - 11.5). In the release of calcium, the use of the antimicrobial polyhexamethylene guanidine hydrochloride (PHMG) did not interfere with the release of calcium from the material. Conclusion: The addition of (PHMG) to the calcium hydroxide powder and to the propylene glycol vehicle did not interfere with the release of calcium, besides having an antimicrobial effect, it maintained the alkaline pH, without altering the film thickness, however presented a lower material flow.
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Análise histológica, histomicrobiológica e radiológica de dentes de cães com necrose pulpar, induzida experimentalmente, submetidos a diferentes materiais dentáriosDomingues, Lèslie Maria [UNESP] 17 December 2002 (has links) (PDF)
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domingues_lm_dr_jabo.pdf: 366856 bytes, checksum: 52256d4f85a43bd13c671e6a70de6717 (MD5) / Objetivou-se avaliar a presença de microrganismos nas estruturas dentais com necrose pulpar induzida experimentalmente, testando a eficácia de materiais com relação à atividade antibacteriana e influência no reparo tecidual. Utilizaram-se quatro cães, totalizando 78 raízes, provenientes de pré-molares, divididas em grupos. O Grupo I foi obturado com guta percha e cimento à base de óxido de zinco e eugenol, o Grupo II, com hidróxido de cálcio com paramonoclorofenol canforado (PMCC), o Grupo III, com hidróxido de cálcio e o Grupo IV, não foram obturados. Todos tiveram controle clínico e radiográfico quinzenal e após 120 dias, foram extraídos em bloco para análises. Observou-se imagem radiográfica radioluscente ao redor das raízes, e após os tratamentos, notou-se diminuição no número de raízes afetadas. A histopatologia evidenciou infiltrado inflamatório, reabsorção cementária e óssea e tecido necrótico no delta apical, em diferentes proporções. A histomicrobiologia revelou presença de microrganismos nas estruturas estudadas, variando de acordo com o tratamento utilizado. Os resultados foram submetidos à análise estatística e não foram significantes entre si. A guta-percha com óxido de zinco e eugenol apresentou-se eficaz com relação à atividade antibacteriana. O hidróxido de cálcio sozinho não se mostrou eficaz, e associado ao PMCC, favoreceu o reparo tecidual. A utilização dessa associação como curativo de demora, para posterior obturação definitiva com guta-percha e óxido de zinco e eugenol, talvez seja a melhor opção para se ter um bom efeito antibacteriano e um adequado processo de reparo tecidual. / The purpose of this study was to evaluate the permanence of microorganisms in dental structures with pulpar necrosis experimentally induced. Four dogs were used, totalizing 78 roots, coming from premolars, divided in four groups. Group I received gutta-percha with zinc oxide cement and eugenol. Group II was treated with calcium hydroxide and camphorate paramonoclorofenol (PMCC). Group III was submitted to calcium hydroxide and group IV had no treatment. All teeth had radiographic and clinical control every 2 weeks and, after 120 days, were extracted in block for analysis. Pulpar exposition had radiographic radioluscent image around roots and, after treatments, there were less affected roots. Histopathological analysis evidenced inflammatory infiltrate, bone and cementary reabsorption and necrosis in apical delta, in different proportion. Histomicrobiological analysis showed presence of microorganisms in apical delta, dentinary tubules, cementary lacunas, radicular canal wall and interior, variating with the treatment used. Statistically the results had no statistic difference. Gutta-percha with zinc oxide and eugenol was effective against microorganisms. Calcium hydroxide alone was not effective in none parameter and, associated with PMCC, was less irritating for periapical tissues, facilitating the tissue repair. The use of this association as delay bandage, for later and definitive obturation with gutta-percha with zinc oxide and eugenol maybe the best option for a good antibacterial effect and a appropriate tissue repair.
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